1. < Heart & Blood Health

Bempedoic acid to lower LDL (non statin)

Posted by naiviv @naiviv, Jul 5 10:16am

Good morning everyone. Has anyone being prescribed Belpedoic acid to lower the LDL and cholesterol? It is a no-statin. My cardiologist mentioned it since I can’t tolerate statins. I tried years ago Crestor 5mg but I started to feel muscle fatigue. I will appreciate if anyone has started this medication and if it is working good.
Thank you
Vivian

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Mentor
Sue, Volunteer Mentor | @sueinmn | Jul 5 5:23pm

Here is what Mayo Clinic recently reported:
https://www.mayoclinic.org/drugs-supplements/bempedoic-acid-oral-route/description/drg-20484223
It seems like it is usually used as an additional drug, but can be used by those who are statin-intolerant as well. I will be asking my cardiologist about it as I have "failed" 3 statins

REPLY
naiviv | @naiviv | Jul 5 5:33pm

Thank you. I would appreciate if you would want to share what the cardiologist thinks about this medication. I have been reading about it but whzt I don’t understand is that some physicians prescribe it with statins which doesn’t make sense when the patient doesn’t tolerate them. Anyway. I will keep an eye on responses. Have a great weekend. Stay healthy and safe. Thanks. Vivian

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1 reply
swilkins1974 | @swilkins1974 | Jul 6 8:49am
In reply to @naiviv "Thank you. I would appreciate if you would want to share what the cardiologist thinks about..." + (show)
@naiviv

Thank you. I would appreciate if you would want to share what the cardiologist thinks about this medication. I have been reading about it but whzt I don’t understand is that some physicians prescribe it with statins which doesn’t make sense when the patient doesn’t tolerate them. Anyway. I will keep an eye on responses. Have a great weekend. Stay healthy and safe. Thanks. Vivian

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What I understand about when a cardiologist prescribes with a statin, is that the patient can only tolerate less milligrams of a statin than they actually need. When you put these two together it can lower cholesterol to an acceptable level.

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vaniag | @vaniag | Jul 6 11:22am

Yes - I have been on it for 2 years. I have had no side effects and it is lowering LDL I am taking Nexletol, the one without Zetia. I had side effects with all statins...

The biggest problem is getting my insurance to cover it. It requires prior approval…and I am also on Repatha - both are expensive and no generics. Other than that…I haven’t had a single problem on it. If you get on it…stay away from Cipro and other fluoroquinolone antibiotics. Can cause tendon rupture.

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