BCG vaccine and non invasive papillary cancer

Posted by mnasrich612 @mnasrich612, Aug 28, 2023

I had a 3 cm papillary non invasive cancer removed by turbt. Dr wants to start me on BCG. Is this the best treatment??

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I did 4 instillations of BCG so far and my doctor did a cytology urine test .which I copy below.can someone please tell.me what it means
Urine cytology, cytospin(s)

PARIS SYSTEM: RARE ATYPICAL UROTHELIAL CELLS, see comment

COMMENT: The specimen is hypocellular and contains rare atypical cells.

Reference:
Rosenthal DL., Wojcik EM., Kurtycz DFI: “The Paris System For Reporting Urinary Cytology”: 2016.

Categories and the Implied Risk of Malignancy:
Unsatisfactory / Nondiagnostic, (< 5%)
Negative for HGUC, (0-10%)
Atypical urothelial cells, (8-35%)
Suspicious for high grade urothelial carcinoma, (50-90%)
High grade Urothelial carcinoma, (>90%)
Low grade Urothelial Neoplasm, (~10%)
Other malignancies, Primary and Secondary, (>90%)

NOTE: One or more of the slides from this case were reviewed by one or more additional Pathologists for Quality Review purposes.

REPLY
@mnasrich612

I did 4 instillations of BCG so far and my doctor did a cytology urine test .which I copy below.can someone please tell.me what it means
Urine cytology, cytospin(s)

PARIS SYSTEM: RARE ATYPICAL UROTHELIAL CELLS, see comment

COMMENT: The specimen is hypocellular and contains rare atypical cells.

Reference:
Rosenthal DL., Wojcik EM., Kurtycz DFI: “The Paris System For Reporting Urinary Cytology”: 2016.

Categories and the Implied Risk of Malignancy:
Unsatisfactory / Nondiagnostic, (< 5%)
Negative for HGUC, (0-10%)
Atypical urothelial cells, (8-35%)
Suspicious for high grade urothelial carcinoma, (50-90%)
High grade Urothelial carcinoma, (>90%)
Low grade Urothelial Neoplasm, (~10%)
Other malignancies, Primary and Secondary, (>90%)

NOTE: One or more of the slides from this case were reviewed by one or more additional Pathologists for Quality Review purposes.

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Please do yourself a favor and ask your physician what exactly this means.

REPLY

Thanks @richardab. I will follow your advice

REPLY
@mnasrich612

I did 4 instillations of BCG so far and my doctor did a cytology urine test .which I copy below.can someone please tell.me what it means
Urine cytology, cytospin(s)

PARIS SYSTEM: RARE ATYPICAL UROTHELIAL CELLS, see comment

COMMENT: The specimen is hypocellular and contains rare atypical cells.

Reference:
Rosenthal DL., Wojcik EM., Kurtycz DFI: “The Paris System For Reporting Urinary Cytology”: 2016.

Categories and the Implied Risk of Malignancy:
Unsatisfactory / Nondiagnostic, (< 5%)
Negative for HGUC, (0-10%)
Atypical urothelial cells, (8-35%)
Suspicious for high grade urothelial carcinoma, (50-90%)
High grade Urothelial carcinoma, (>90%)
Low grade Urothelial Neoplasm, (~10%)
Other malignancies, Primary and Secondary, (>90%)

NOTE: One or more of the slides from this case were reviewed by one or more additional Pathologists for Quality Review purposes.

Jump to this post

Hi @mnasrich612, I assume you've met with your oncologist in the meantime. May I ask, what did you learn at that appointment? Will you continue with BCG treatment?

REPLY

The oncologist said no cancer cells were found in the cytology report
He suggested that I already completed 4 instillations and I can hold off from the remaining 2. He emphasize that I need to get a CYSTOCOPY done within. 4 to 6 weeks

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Interesting. I have a 1.5 mm papillary tumor. I have TURBT scheduled in about 5 weeks, the urologist has said he would flood the bladder with chemo or BCG after the tumor has been removed. Additional treatments would be scheduled depending on the extent of the tumor and the biopsy. So your oncologist didn't apply the BCG at the time of the TURBT?

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Yes my oncologist applied GENZAR a chemotherapy drug immediately after the surgery. My bladder was flooded and I could not hold it in my bladder for very long.

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