Autoimmune hepatitis: Questions about treatment and transplant

Posted by nativargas @nativargas, Jun 25, 2024

I’m 34, I’ve diagnosed HIA 23 year ago. Also hashimoto, and Sörgen.
Now my liver is with cirrosis and my treatment base is prednisone + metfomyne + diuretics +rifaximina. I’m expecting a transplant but I’m so afraid about it.

Interested in more discussions like this? Go to the Autoimmune Diseases Support Group.

Profile picture for steph740 @steph740

I have Autoimmune hep since 2006, been on azathioprine since then. Never had any side effects. I'm currently on 200mg daily. I usually do no have side effects from any drugs. Sorry your going thru that.

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@steph740 Welcome to Mayo Clinic Connect. I’m glad that you found this site! You say that you have autoimmune hepatitis and have had it since 2006. Several discussions are currently
https://connect.mayoclinic.org/discussion/autoimmune-hepatitis-10/
Taking place on Connect. The above is current now and I’m sure they would love your joining them.

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Profile picture for chopin002 @chopin002

Diagnosed with autoimmune hepatitis .
Already have PMR , GCA, and Graves’ disease.
Taking a pass on treatment. The drugs sound worse than the condition and I am 71 years old. I believe 5-10 good years better than 10-20 poor, sickly years. Any try AZA without side effects. Already taken prednisone for 7 years and finally down to one mg. Staying there.

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Hi. I just got diagnosed with my 5th autoimmune disease and have some questions. I had a liver biopsy 2 1/2 weeks ago after my liver enzymes started rising in February and spiked in March and slowly started coming back down. Still a little high. Ultrasound was normal. MRI/MRCP was normal. Liver biopsy ordered. Results just came back this week as Chronic Autoimmune Hepatitis. F 3/4. I am allergic to Steroids/Corticosteroids. (Causes steroid-induced psychosis). Is there anyone who is familiar with non-steroidal treatment options and their effectiveness? I have a referral that was sent in to a specialized Hepatologist four hours away. Gastroenterologist said it will probably take several months to get in as a new patient to Hepatologist. So, in the meantime, I will be untreated. How could my liver get this much damaged in only a few months? Any information or tips/tricks on non-steroidal treatment appreciated. Thanks in advance.

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Profile picture for ksblonde @ksblonde

Hi. I just got diagnosed with my 5th autoimmune disease and have some questions. I had a liver biopsy 2 1/2 weeks ago after my liver enzymes started rising in February and spiked in March and slowly started coming back down. Still a little high. Ultrasound was normal. MRI/MRCP was normal. Liver biopsy ordered. Results just came back this week as Chronic Autoimmune Hepatitis. F 3/4. I am allergic to Steroids/Corticosteroids. (Causes steroid-induced psychosis). Is there anyone who is familiar with non-steroidal treatment options and their effectiveness? I have a referral that was sent in to a specialized Hepatologist four hours away. Gastroenterologist said it will probably take several months to get in as a new patient to Hepatologist. So, in the meantime, I will be untreated. How could my liver get this much damaged in only a few months? Any information or tips/tricks on non-steroidal treatment appreciated. Thanks in advance.

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I try to be careful with my liver since I had hepatitis C for 20 years undiagnosed. I was recommended a supplement called “super thisilyn.” you asked a question about how this could happen so quickly and I can tell you from recent experience. I had gastroenteritis and my liver enzymes shut up through the roof so I went and bought a liver detox cleanse supplement that I used for a few days to hopefully bring that down the inflammation. The liver is an amazing organ as it can regenerate from sclerosis, if not too severe. I don’t know if you’ve looked at your diet to bring down your inflammation. Gluten is a biggie that should be avoided and fats and your sugars should be balanced. you might want to try a natural healing route and acupuncture if you haven’t thought about it. Also non-western medicines can be very helpful. The western medicines are very toxic to a delicate system.

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Profile picture for loriesco @loriesco

I try to be careful with my liver since I had hepatitis C for 20 years undiagnosed. I was recommended a supplement called “super thisilyn.” you asked a question about how this could happen so quickly and I can tell you from recent experience. I had gastroenteritis and my liver enzymes shut up through the roof so I went and bought a liver detox cleanse supplement that I used for a few days to hopefully bring that down the inflammation. The liver is an amazing organ as it can regenerate from sclerosis, if not too severe. I don’t know if you’ve looked at your diet to bring down your inflammation. Gluten is a biggie that should be avoided and fats and your sugars should be balanced. you might want to try a natural healing route and acupuncture if you haven’t thought about it. Also non-western medicines can be very helpful. The western medicines are very toxic to a delicate system.

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@loriesco I am a severe celiac and have been on a strict gluten free diet since 2023. I also have MCAS, so I am on a low histamine diet for that.
I will look into acupuncture while waiting on hepatology appointment.
Thanks so much for your response.

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