1. < Depression & Anxiety
Profile picture for cmarts

Anyone taking Mirtazapine? Is it working for you? Any side effects?

Posted by cmarts @cmarts, Mar 4, 2025

Has anyone been taking Mirtazapine? Like to know if they have taken themselves off and how did you do it?

Interested in more discussions like this? Go to the Depression & Anxiety Support Group.

Profile picture for mitch4444
mitch4444 | @mitch4444 | May 26 9:54am
In reply to @sl2485 "@mitch4444 so essentially at 15mg it’s pretty much just a sleep aid? I was at 30mg..." + (show)
Profile picture for sl2485 @sl2485

@mitch4444 so essentially at 15mg it’s pretty much just a sleep aid? I was at 30mg until 18th April and doing OK, I then dropped to 15mg and was good at first but last couple of weeks have been hell with anxiety and fatigue. I dropped to 50mg of sertraline back in February so I’m pretty sure it’s not that.

Jump to this post

@sl2485
Also some medication takes longer to leave your system. Keep trying!

REPLY
Profile picture for visionsofelvis
visionsofelvis | @visionsofelvis | Jun 3 4:31pm
In reply to @ladydi82 "Hello, I’ve been on mirtazapine since March 2025. I was on 15mg, but as of last..." + (show)
Profile picture for ladydi82 @ladydi82

Hello, I’ve been on mirtazapine since March 2025. I was on 15mg, but as of last night I am on 7.5mg. I want to completely taper off. How long should I stay on 7.5mg by experience before stopping completely? Like I mentioned, I haven’t been on it long. Thanks!

Jump to this post

I’ve been on mirtazapine since January 8. Started on 15 mg for sleep was on that dose for 3 months then dropped to 7.5 for 7 weeks now on 3.75 mg for two weeks.my psychiatrist as of two weeks ago put me on busiprone 10 mg twice day to help with my anxiety and to assist weaning off 3.75 mg. Has anyone just dropped 3.75 after two weeks even after busiprone has not kicked in yet?

REPLY
Profile picture for cynthiaefs
cynthiaefs | @cynthiaefs | Jun 4 10:07am
In reply to @ladydi82 "Hello, I’ve been on mirtazapine since March 2025. I was on 15mg, but as of last..." + (show)
Profile picture for ladydi82 @ladydi82

Hello, I’ve been on mirtazapine since March 2025. I was on 15mg, but as of last night I am on 7.5mg. I want to completely taper off. How long should I stay on 7.5mg by experience before stopping completely? Like I mentioned, I haven’t been on it long. Thanks!

Jump to this post

No specific experience but tapering off schedule sounds very reasonable. Good luck.

REPLY
Profile picture for soozejb
soozejb | @soozejb | Jun 16 12:37pm
In reply to @ladydi82 "Hello, I’ve been on mirtazapine since March 2025. I was on 15mg, but as of last..." + (show)
Profile picture for ladydi82 @ladydi82

Hello, I’ve been on mirtazapine since March 2025. I was on 15mg, but as of last night I am on 7.5mg. I want to completely taper off. How long should I stay on 7.5mg by experience before stopping completely? Like I mentioned, I haven’t been on it long. Thanks!

Jump to this post

I've been taking mirtazapine for 15 years, mostly at a dose of 15 mg. I've finally decided I'm done with the appetite and weight gain issues and want to wean myself off of it. My psychiatrist who originally prescribed it for depression is on leave. I've reduced to 7.5 as of yesterday and would like some guidance on how to proceed with tapering. I know that the length of time I've been taking it makes it more difficult to stop. Thank you to anyone who can advise about this. Thank you!

REPLY
1 reply
Profile picture for visionsofelvis
visionsofelvis | @visionsofelvis | Jun 16 6:27pm
In reply to @soozejb "I've been taking mirtazapine for 15 years, mostly at a dose of 15 mg. I've finally..." + (show)
Profile picture for soozejb @soozejb

I've been taking mirtazapine for 15 years, mostly at a dose of 15 mg. I've finally decided I'm done with the appetite and weight gain issues and want to wean myself off of it. My psychiatrist who originally prescribed it for depression is on leave. I've reduced to 7.5 as of yesterday and would like some guidance on how to proceed with tapering. I know that the length of time I've been taking it makes it more difficult to stop. Thank you to anyone who can advise about this. Thank you!

Jump to this post

@soozejb I’m not a dr just a patient like you. 10 years is a long time. I’ve been on mirt for 5 months total. First 15 mg for 3 months, 7.5 for 7 weeks and now cut 7.5 to 3.75 now for 4 weeks tomorrow. For you stay on 7.5 until it settles and stabilizes. I can’t tell you how long but most psychiatrists will say just wean as long as you can then stop. You don’t want to stop abruptly! Anxiety will kick in. I’m still on 3.75 mg as my dr put me on busiprone 10 mg twice a day to help come off it. Stay in touch

REPLY
2 replies
Profile picture for bern7475
bern7475 | @bern7475 | Jun 17 10:39am
In reply to @visionsofelvis "@soozejb I’m not a dr just a patient like you. 10 years is a long time...." + (show)
Profile picture for visionsofelvis @visionsofelvis

@soozejb I’m not a dr just a patient like you. 10 years is a long time. I’ve been on mirt for 5 months total. First 15 mg for 3 months, 7.5 for 7 weeks and now cut 7.5 to 3.75 now for 4 weeks tomorrow. For you stay on 7.5 until it settles and stabilizes. I can’t tell you how long but most psychiatrists will say just wean as long as you can then stop. You don’t want to stop abruptly! Anxiety will kick in. I’m still on 3.75 mg as my dr put me on busiprone 10 mg twice a day to help come off it. Stay in touch

Jump to this post

@visionsofelvis following because I am in the same situation. I will be interested in what kind of answers you get! Hang in there

REPLY
1 reply
Profile picture for visionsofelvis
visionsofelvis | @visionsofelvis | Jun 17 8:31pm
In reply to @bern7475 "@visionsofelvis following because I am in the same situation. I will be interested in what kind..." + (show)
Profile picture for bern7475 @bern7475

@visionsofelvis following because I am in the same situation. I will be interested in what kind of answers you get! Hang in there

Jump to this post

@bern7475 I plan to do 3 more days on 3.75 then stop mirt

REPLY
1 reply
Profile picture for marz560
marz560 | @marz560 | Jun 23 11:31am
In reply to @visionsofelvis "@bern7475 I plan to do 3 more days on 3.75 then stop mirt" + (show)
Profile picture for visionsofelvis @visionsofelvis

@bern7475 I plan to do 3 more days on 3.75 then stop mirt

Jump to this post

@visionsofelvis same.. my issues are with the “hangover” I feel every morning until almost noon.. I hate it so, I’m gonna wean myself off asap

REPLY
1 reply
Profile picture for ellesea01
ellesea01 | @ellesea01 | Jun 23 12:19pm
In reply to @visionsofelvis "@soozejb I’m not a dr just a patient like you. 10 years is a long time...." + (show)
Profile picture for visionsofelvis @visionsofelvis

@soozejb I’m not a dr just a patient like you. 10 years is a long time. I’ve been on mirt for 5 months total. First 15 mg for 3 months, 7.5 for 7 weeks and now cut 7.5 to 3.75 now for 4 weeks tomorrow. For you stay on 7.5 until it settles and stabilizes. I can’t tell you how long but most psychiatrists will say just wean as long as you can then stop. You don’t want to stop abruptly! Anxiety will kick in. I’m still on 3.75 mg as my dr put me on busiprone 10 mg twice a day to help come off it. Stay in touch

Jump to this post

@visionsofelvis

Exactly. Slowly. Ran my basic plan past 2 of my doctor's. Slow has worked quite well so far about
8 months in. A few ugh the last few days might not be related. Dealing with it by adjusting activity output. Glad you added a keep in touch note.
Appreciate your input.

REPLY
Profile picture for visionsofelvis
visionsofelvis | @visionsofelvis | Jun 23 12:19pm
In reply to @ladydi82 "Hello, I’ve been on mirtazapine since March 2025. I was on 15mg, but as of last..." + (show)
Profile picture for ladydi82 @ladydi82

Hello, I’ve been on mirtazapine since March 2025. I was on 15mg, but as of last night I am on 7.5mg. I want to completely taper off. How long should I stay on 7.5mg by experience before stopping completely? Like I mentioned, I haven’t been on it long. Thanks!

Jump to this post

I stopped 3 days ago so far so good

REPLY
1 reply
Please sign in or register to post a reply.