Tapering off mirtazapine

Posted by ladydi82 @ladydi82, Aug 24, 2025

Hello, I’ve been on mirtazapine since March 2025. I was on 15mg, but as of last night I am on 7.5mg. I want to completely taper off. How long should I stay on 7.5mg by experience before stopping completely? Like I mentioned, I haven’t been on it long. Thanks!

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visionsofelvis | @visionsofelvis | Jun 23 12:19pm

I stopped 3 days ago so far so good

Lisa Lucier, Moderator | @lisalucier | Jun 23 1:38pm

In reply to @visionsofelvis "I stopped 3 days ago so far so good" + (show)

@visionsofelvis - are you still on the buspirone, or is your doctor prescribing something else? Did the buspirone help?

visionsofelvis | @visionsofelvis | Jun 23 2:45pm

yes I'm om busiprone yes its helping

joetex | @joetex | Jun 24 6:52am

In reply to @marz560 "@visionsofelvis same.. my issues are with the “hangover” I feel every morning until almost noon.. I..." + (show)

@marz560 Part of the hangover is because of the low dose. With mirtazipine the lower the dose the more the sleep effect. It works backwards from other medications for sleep issues. I would get a doctor’s opinion.

marz560 | @marz560 | Jun 24 8:05am

In reply to @joetex "@marz560 Part of the hangover is because of the low dose. With mirtazipine the lower the..." + (show)

@joetex I am meeting with her Friday morning.. I think that’s part of what I dislike about this medication.. she started me at a higher dose and the hangover was worse than what I’m experiencing at 7.5 yes, it’s addressed my insomnia, but it’s not worth how much of my daytime routine has been affected by it. I want off asap and am hoping she has other medications options for me to explore.. thanks

visionsofelvis | @visionsofelvis | Jun 24 10:29am

Anyone experience some withdrawal once mirtazapine is stopped? First 3 nights off with little anxiety however last night harder to go to sleep. Dr prescribed Trazodone 50 mg along with buspar 10 mg twice a day for buspar.

joetex | @joetex | Jun 24 11:10am

In reply to @marz560 "@joetex I am meeting with her Friday morning.. I think that’s part of what I dislike..." + (show)

@marz560 I remember that sluggish feeling. Mine lasted 4-5 weeks and then I adjusted. I didn’t think I ever would but I finally did. Good luck.

marz560 | @marz560 | Jun 24 12:21pm

In reply to @joetex "@marz560 I remember that sluggish feeling. Mine lasted 4-5 weeks and then I adjusted. I didn’t..." + (show)

@joetex I actually did adjust and then just like that, it hit me again.. I’m actually upset by this because it does help me sleep.. idk, will see what my dr thinks

visionsofelvis | @visionsofelvis | Jun 24 8:59pm

In reply to @joetex "@marz560 I remember that sluggish feeling. Mine lasted 4-5 weeks and then I adjusted. I didn’t..." + (show)

@joetex what was your dose when you stopped? How long were you on mistazapine

joetex | @joetex | Jun 24 9:47pm

In reply to @visionsofelvis "@joetex what was your dose when you stopped? How long were you on mistazapine" + (show)

@visionsofelvis I am still on the 15mg. I started at 7.5mg for a few weeks then went to 15mg about 2 months ago. It took me 5 or 6 weeks to get over the tiredness but am okay now. But my appetite is going crazy. I don’t like that.