Learn how to use Mayo Clinic Connect
Request an Appointment
Anyone here dealing with peripheral neuropathy?
Interested in more discussions like this? Go to the Neuropathy group.
I am on 800mb three times a day and it does not even touch the pain I am in, anyone have any suggestions on a good pain medicine that will stop extreme pain?
Jump to this post
I find Tramadol works for me when my pain is too, too much. Talk with your doctor about prescribing Tramadol.
@grandma41 I have never heard of 2 ingredients you mentioned!
Pain away drops
Where are these found if you do not mind sharing. Thank you
I found that Palmitoylethanolamide (PEA) worked wonders for me. This is all natural with no side effects and is used for all forms of neuropathic pain. (I am unable to tolerate most prescription drugs.) I take it twice a day (400mg per pill) and sometimes 3 times a day when I have a bad flare-up. It took about 3-4 weeks before it became effective and I couldn't live without it now. You can buy it on Amazon. Look for the unadulterated form (without additives) like OptiPure, PEA-Cure, Ergomax. Trials have used up to 2000 mg/day for chemo-induced neuropathy. The unadultered form mostly comes from The Netherlands.
Hi Elizm. I just started using PEA, about 4 days ago, and I am praying it will help. I just happened upon hearing about it here. Someone was talking about it, and I started researching it, and finally bought it. Next time, I will buy the ones you suggested. I am starting on 800 mg., twice daily, for one month. I heard a Doctor from the Netherlands suggest that if you do not get relief on that dosage in a month, you can double that the next month, before giving up on it, so that is what I will do. That was from a video on you tube. I also learned that it must be taken with some sort of fat in your meal, to make sure it is absorbed. Have you heard that? Do you do that? I just read that from one person on an Amazon review. Anyway, it was utterly fabulous to read your post, and hear that you have had success. I hope that I do as well, because living in pain is utterly terrible…. Lori Renee
Blessings, Lori Renée, and best of luck!
Thanks so much!!!! Lori
Hi, this is the first I have heard of this. I'm struggling with symptoms but prefer to take natural. I wonder if PEA is available in Australia.
Before I found PEA, I had gone to a Doctor of Chinese medicine who performed acupuncture. I hated the acupuncture in my hands, legs and feet, so he recommended Zhi Bai Di Huang Wan, an herbal pill, which traditionally (like for 200 years) is given to menopausal women to help with hot flashes. Interestingly, it helped with the burning in my hands and feet (turned them icy cold) and allowed me to sleep for the first time in six months since I had started chemo. As I am unable to tolerate most prescription meds, it's natural composition (something like 6-7 roots) fit the bill. About another six months later, I started reading about PEA. There was a month's transition between the herbs and PEA and then I stayed with the PEA. So if you can't find PEA (on Amazon, for example), you might want to try the Zhi Bai Di Huang Wan.
The Doctor of Chinese medicine also counseled me to keep both in stock as one's nervous system can get used to one and efficacy can diminish, and it's nice to be able to switch or supplement with the other.
Thankyou @elizm for your reply. In the past, I had been taking zoloft which seems to mask pain perception. I didn't tolerate any other pain meds like lyrica or gabapentin as the effects caused grogginess & STML. I still have some capacity to hold down a job but with these neuropathy symptoms, I'm at my wits end. I will research PEA, & perhaps CBD oil.
My doctor said that Gaba and Lyrica aren't pain killers, they are anti-seizure medications — they calm the nervous system, then the nervous system stops sending out false pain signals (my feet feel like they are on fire but there is no fire touching them, it's a false pain signal). Pain killers kill any pain any where, Gaba and Lyrica won't do that. The difference is important because pain killers are harder to get and have more side effects than anti-seizure meds.
Thanks! I saw my neurologist today, she suggested that I take Tramadol, but she can't prescribe it (in Virginia, maybe in other states a neurologist can). I have to go to a Pain Specialist.
Create an account to connect with other patients and caregivers like you.Ask questions, get answers, and give and get support.Also follow blogs from Mayo Clinic experts.
Already have an account? Sign In