Antidepressant Duloxetine side effects tough, any suggestions?

Hi. I started Wellbutrin but experienced increased blood pressure. I stopped taking them. I was only on a few days. Did you experience this side effect? Thanks

Not that I know of (although, that was about when my primary put me on blood pressure meds for borderline high blood pressure). I had sores in my mouth. When I told the doctor, she acted like it was impossible the Wellbutrin was causing this. After I was off it (and the sores went away) I looked it up on drugs.com, and it's a known side effect. Argh.

I put myself on a low carbohydrate diet and started walking several hours every day and within a year I not only lost weight, but vanquished all symptoms of clinical depression, sans any drugs, chemicals, herbs, supplements, or prescribed medications!!! Any amount of alcohol will derail your progress!!! Psychoactive street concoctions are even more deleterious !!! 😇

You are welcome to do with your body as you choose. My dieting experience is weight cycling, ending up gaining more than I lost each time - which, of course, is the experience of most dieters over a 5 year period. I do water aerobics three times a week. And I still have clinical depression and other various health issues, and lost no weight until I went on Mounjaro for my type 2 diabetes (which is genetic as it runs in both sides of my family). Aren't you lucky that you don't need any chemical help; but I am sure you realize that your experience is your experience and not those of others.

Mombo, my rheumatologist has put me on Lamictal for pain, but says it also is a fine depression helper. But she also told me 60 mg of Cymbalta (duloxitine), twice a day was the best thing to do..the Lamictal is a helper. And it's an anti-anxiety med, and doesn't interfere with any other of my meds, and it's an anti-inflammatory. She also put me on Medical marijuana, but told me it's tricky to find the right combination and the right dosing/timing to avoid too much of a high, so I'll be working closely with a Pharmacist at a Med mj dispensary to work that out over time. Both Doc and Pharmacist sounded extremely poitive about it and aware that some folks are wary of the bad reputation it's gotten from too many stinky high-as-a-kite users of it as a recreational product, and unaware of a very very long history of medical research and use. Ask your Rheumatologist beore you give up on anti-depressants. She may just end up sending you elsewhere, but sending to someone who knows is good, right? 😁😁🤞

I had serious side effects
I'm still not well.

I lost my ability to speak and had no control over my body movements

I've had no support not even offered a stroke scan to eliminate that.

BE CAREFUL ASK ALOT OF QUESTIONS WE HAVE NO LEGAL STANDING BEING MENTALLY ILL AND ILL FROM MEDICATIONS

@jennax Welcome to Mayo Clinic Connect! And how did you find us? I’m glad that you did find this site! Let’s hope we can help you! There must be a sentence missing somewhere and it mentioned that you were on Duloxatine. Is that right? I would suggest that you call or visit the person who wrote the prescription. They NEED to know how it affected you. I, too, was put on Duloxatine as an adjunct to my antidepressant. Luckily, I didn’t have the same reaction as you, but I took myself off anyway. Just didn’t like how it made me feel. That’s enough about me! I suggest that you also call the company that made the medicine. They are supposed to keep written documentation of any serious side effects.
You also said “no legal standing being mentally ill” Are you mentally ill? If you have a caseworker or doctor who keep an eye one you, you might also let them know about your reaction.
Are you getting speech therapy or physical therapy to help?
Enough from me! Let’s let others give you their two-cents worth!

@bruizersmom
Took Cymbalta once. doctor had assured me that this would not have problems. He was wrong. Extremely depressed. Refused to take it again.
Took Lamictal for 2 years because doctor was trying to evaluate for bi-polar. Not sure why your doctor is using this medicine. Maybe talk to someone else?
Trust your own judgement and understanding of your own body. Listen to your body - you know it best

@ailsas , you said you were put on Lamictal. I was put on it because it is a mood smoother, appropriate for me, since I was having totally good, maybe a bit more like manic-good, and then totally black days. It did the job for me, lessening my sudden anger outbursts, and curbing me from having impossibly loud joyous crazy days (which annoyed many others). Shortly after starting on the med, I mentioned my change in medications to my epileptologist who then upped my dose to where it could manage my seizures and eliminate a schedule 4 drug I was taking. I was also warned that for most folks, this medication kicked in very slowly, and at both dosage I was put on a very slow taper to full dose. I've never heard of Lamictal used as a pain med! If it is, well it didn't act that way for me; I still have severe back pain, foot pain and belly pain. Oh well. Sorry for the Cymbalta. I'm on it for depression and it's been fine now.

@jennax , every one of my medications come with an adverse-reaction warning as well as a note to contact the phone number listed, as well as your Primary Care or prescribing physician. I don't understand why you say yoou have no "legal standing." Do you mean Legal Recourse? You sure do! If any harm was done (looks that way), you can alwayd look for a pro-bono Attorney to file for damages, etc.
Did you notify your drug company, pharmacist, or physician? If you did, there was obviously a mishandling of your case (another lawsuit?) that should also be addressed by someone with medical experience.