Side Effects: Amiodarone vs Sotalol

Thanks for your reply. I was thinking specifically of physical activity and I think you are confirming my hypothesis. Though I have no doubt that the other activities are beneficial, as well. I am still able to engage in lots of the other, just not much of the physical. But I am encouraged to keep trying. I wonder whether anyone is researching this question: are the effects of Sotalol on non-cardio beta receptors mitigated by physical exercise. A question for @amandaa, perhaps.

Might I ask why you and your docs are not keen on ablation. I am on Sotalol for my Afib and find myself very tired because of this drug. With Amiodarone I found my Afib to be under control and no tiredness.

I think I answered your question in my August 18 post so I will just try to summarize now: I also have coronary artery disease and also a very high risk of stroke with likely a severe outcome in the event of stroke. So Sotalol may be the best option for me, the jury is still out . . .

I don't think ablation is a good option as everyone I know that has had ablation have had several repeats. That is fine for whoever is doing it, but it sure affects your insurance.
I am on Amiodarone, supposed to be on 200mg a day. That kills my energy and caused a lot of other irritations in my daily life. I did a lot of studying and read a paper on the efficiacy of 100mg compared to 200mg. After 18 months I cut the pills in half, 100mg a day. Feel a lot better but still wary of this drug. My primary calls it poison and my cardiologist wants me to switch to Sotalol. I might not be a doctor but I can read and my comprhension skills are good. I personally am holding off on that switch which would require that I stop Metoprolol 2 x 100mg and the Amiodarone and go on bidaily Sotalol.
It's all poison. My current regimen is 2.5mg Amlodipine, 200mg Metoprolol and 120mg Verapamil and 100mg Amiodaroneper day. I think I am starting to get blurred vision and last US shows Pancreatic issues.

My e-cardiologist wants to put me on sotalol for my PVC's. I see it being used to treat Afib, but not PVC's. Anybody have any experience with it for PVC's??

I’ve been on Sotolol for years for my AFib.

Wow it seems like you are on a lot of medication. I am currently on 100 mg of amiodarone (lowered from 200 to 100 by dr upon my request) for the last 6 months. Also Xarelto. Have paroxysmal Afib. Amiodarone has stopped the 2x month episodes I was having the last year. They say it is a "short term" drug and want to do an ablation (looking at February). Not sure how short "short term" means. I continue to be short of breath a lot, have gained 10 lbs since starting it and sometimes have various aches and pains (but that may be "old age"? I'm 81).

Trying this for 2nd time.
I now take Sotalol and Verapamil 2 x daily. No more Metoprolol, or Amiodarone. Sotalol replaces both. I feel great. The Amiodarone made me feel out of brearh. My NP called it poison and sent me to new cardiologist. The verapamil I take as it keeps my heart muscles from hardening further. I also take 2.5 mg Amlodipine daily. Haven't had afib in over 2 years. Heart rate around 60 or less BP is good. Not out of breath. Can run if I want.

Sotalol effects both rate and rhythm; it's one option for PVCs - and maybe data from Mayo would be useful for you - link below - good luck!
https://www.mayoclinic.org/drugs-supplements/sotalol-oral-route/description/drg-20071203

It is so interesting to have this Sotalol thread show up today -- I just heard from my EP this week and he has diagnosed "chronotropic insufficiency," that's his explanation for my Sotalol symptoms. It does such a good job of slowing my heart! I've said that's acceptable, given that ablation is not an attractive alternative for me and I consider Amiodarone a last resort. So he has suggested a pacemaker. Just wondering whether anyone else has considered that option: Sotalol and a pacemaker.