18 month old with recurrent viral infections
18 month old daughter with 25+ infections/recurrent fevers. 6 ear infections with PE tubes placed at 6 months, hand foot and mouth a few weeks after tubes, rsv, and flu. More recently illnesses have look like high temperatures (102-105.6) with runny nose/congestion sometimes but more often no other symptoms. Every time she is brought to the doctor or these episodes they always run the normal RSV, Strep, and Influenza A/B tests… all are ALWAYS negative. Episodes were every 2-3 weeks and are now every 10 days on the dot. During high fever episodes she is lethargic, shaky, miserable, moans and just wants to be held or sleep. It is a blessing that she has not had febrile seizures. Temps come down to low 100s with tylenol and motrin. X-ray of sinuses showed sinus infection, which we thought we had the answer but two weeks exactly she was sick again with her typical temps.
For example, since April 1st she was hospitalized for a week with adenovirus. In the hospital chest x-ray showed probable pneumonia and prior to d/c CT (yes CT on an 18 month old) was done and showed that her sinuses are clear. Ultrasound of her kidneys and bladder completed in the hospital which looked fine. Urine samples did not grow anything so UTIs are ruled out. Following discharge, she had croup two weeks later while on antibiotics, two days after croup she had an ear infection, two weeks after ear infection she had five days of unexplained fevers (tested negative for RSV, Influenza A/B and strep), two days after fever broke she threw up six times and then slept for 14 hours straight. Ten days after throwing up she spiked her normal 104 temperature, green snotty nose (she has had a runny/snotty nose for a few days). Has a peanut allergy, irrigate nose at night and has a prescribed nasal spray am/pm and on montelukast.
She been to two different immunologists as well as a rheumatologist. Blood panels recently done and showed ANA- 1:160, elevated CRP levels and that she is anemic (she eats a lot of meat but I know it is common). Immunology has ruled out immunodeficiency’s and rheumatology has ruled out autoimmune disorders. Both refer us back to the other or say she is “normal”. We do not feel like we are getting answers as to why she is getting so ill so frequently and routine.