How long do Lupron side effects last after treatment concludes?

I really appreciate this positivizes

I feel great but was concerned after 18 months if it stops working

Stats say 6% chance of living 5 years if distant in bones 30% otherwise

This is exactly what my radiation oncologist said when I asked the same question. So by staying on ADT drugs for a year after radiation is finished, what is accomplished?

Once the radiation therapy is finished, and some time period after while it's still working, isn't this simply postponing the inevitable? You decimate the cells only while your on the drugs, but when you stop, if they are still there undamaged by the radiation....they can start to grow again.

My surgeon prescribed the orgovyx for two years. My RO says 6 mos is a reasonable amount of time. I don't know which one to believe is best at this point. A lot is going to be determined by my next full blood test. If the orgovyx is bringing up liver enzymes and blood sugar etc.. I may stop and see what happens.

Anyone have any experience / knowledge they can share regarding this?

Thank you . I’ve already had salvage radiation without Hormone Therapy. So my next treatment for my recurrence will be Lupron according to my oncologist and urologist. Did not know if it would kill any of the cancer cells.

My Xtandi cost 3,719 a month CDN and all covered I get now Xgeva foe calcium into the bones 700 every 3 mos injection Back on Zolodex every 3 mos at 1,220 a mos all covered

So wrong Cost in Canadian $ is $3,719 all paid for by Ontario Hospital Insurance plan and free over 65 else private EE ER plans have to kick in about $400 We do pay for OHP monthly below 65 but its a big insurance plan for all Each province has own deal

I just came off ADT (Lupron & Abiraterone) a week ago after 18 months. I'm not sure what, if anything, I was expecting right away, but my fatigue, anxiety, and depression kicked up this week. After reading the other comments, it appears the side effects of no-T and Lupron are still clear and present. I will say, though, that while my hot flashes during treatment were minor and infrequent, they have really kicked up this past week-I'm more hot than ever and its winter in NY. Something kicked in my depression also, which came about related to cancer, radiation, and ADT- I had never felt it before being diagnosed and treated, or at least on this level. I had been feeling great for awhile (KAT), but things went sideways this week, a noticeable change in energy and drive. Will be #patient. Stay positive guys.

I came off of Lupron and Casadex 2 months ago after 2years.. had radiation 2years ago.
I continue to experience some fatigue and hot flashes during the night.
Psa readings are undetectable.. stay active with exercise to fight through the fatigue…not fun BUT better than advanced prostate cancer

Agreed on exercise. I had LOW energy coming out of the spring. The guidance was "exercise to get more energy", which was paradoxical since I had no energy to exercise. However, I pushed through it with daily swimming then weight-bearing a few months ago and it really helped. I also had 5 weeks of radiation back in January/February- that was rough at the end, but did a lot of work: diet, qigong, meditation, reiki, exercise and felt much better. I'm feeling better this morning actually from discussing this all.

I was first diagnosed and had surgery in 2015. We thought we got it all, but a year later my PSA rose and I underwent a similar protocol as you, ( Lupron, radiation, 2 years of casodex) in 2016-17. In 2018 my cancer returned ( PSA increasing) several times and I was able to successfully supress it with Intermittent treatments of Lupron and casodex treatment for three months. The first time my PSA dropped for 14 months, then started to rise and we treated again. The second and third times i got 9 months and then 6 months of supression. Now my PSA has again risen and my cancer has been diagnosed as CRT ( castration resistant cancer) and I am moving from intermittent treatment to continuous treatment of Lupron every three months. My side effects are minimal, with some tiredness and hot flashes mostly in the middle of the night, but certainly tolerable. We are now looking at some new drugs and a possible trial. However, when first diagnosed they thought I might live 2-3 years without surgery. I am now entering my 10th year, and with the new drugs available, we are relatively hopeful for another 5+, or maybe even 10. I will be 70 in three weeks, so this is actually more than I had expected, and grateful for every day. No question that this cancer is complicated and at times a bit debilitating, but there is certainly a life worth living with it as well.

I anticipate that I will experience a reoccurring cancer of prostate in the future . It makes sense that you would go back on Lupron and/or Casadex until it stops working… continue the science experiment until it is time to try something else.
More drugs are coming onto the market… I am watching closely to see how others like us are being treated going forward..