How long do Lupron side effects last after treatment concludes?

I actually had Eligard, not Luprin, back in December, plus 3 weeks of Casodex to counteract the expected testosterone bounce. The drugs are essentially the same, but Eligard is a newer version, so the technician giving me the shot explained. And the side effects were negligible to me, so perhaps it's a better option. No night sweats, no muscle loss, and minor weight gain. A little fatigue and libido loss were noticed, but neither were as debilitating as some of the horror stories I've read about.

My RO told me just the other day that, being in the "intermediate unfavorable" category (PSA under 10, Gleason 6 and 7 but a lot of them) and that I did Brachytherapy as well as LDR (15 of 23 down so far), I would not need another injection at this time. YAY!

He also noted that my testosterone should begin to recover in about 3 months, and another PSA test will be done in July or so. Also, since the prostate was not removed, a PSA of about .5 is to be expected, not a 0.05 if RP had been performed. Hey, the prostate is still there, and it has to do something. Still well within limits, but I think he was giving me a heads-up so I don't panic when I get the results back this summer.

Hope you are doing well and that the recovery goes smoothly. That's all any of us can hope for, I suppose.

My Xtandi cost 3,719 a month CDN and all covered I get now Xgeva foe calcium into the bones 700 every 3 mos injection Back on Zolodex every 3 mos at 1,220 a mos all covered

So wrong Cost in Canadian $ is $3,719 all paid for by Ontario Hospital Insurance plan and free over 65 else private EE ER plans have to kick in about $400 We do pay for OHP monthly below 65 but its a big insurance plan for all Each province has own deal

I just came off ADT (Lupron & Abiraterone) a week ago after 18 months. I'm not sure what, if anything, I was expecting right away, but my fatigue, anxiety, and depression kicked up this week. After reading the other comments, it appears the side effects of no-T and Lupron are still clear and present. I will say, though, that while my hot flashes during treatment were minor and infrequent, they have really kicked up this past week-I'm more hot than ever and its winter in NY. Something kicked in my depression also, which came about related to cancer, radiation, and ADT- I had never felt it before being diagnosed and treated, or at least on this level. I had been feeling great for awhile (KAT), but things went sideways this week, a noticeable change in energy and drive. Will be #patient. Stay positive guys.

I came off of Lupron and Casadex 2 months ago after 2years.. had radiation 2years ago.
I continue to experience some fatigue and hot flashes during the night.
Psa readings are undetectable.. stay active with exercise to fight through the fatigue…not fun BUT better than advanced prostate cancer

Agreed on exercise. I had LOW energy coming out of the spring. The guidance was "exercise to get more energy", which was paradoxical since I had no energy to exercise. However, I pushed through it with daily swimming then weight-bearing a few months ago and it really helped. I also had 5 weeks of radiation back in January/February- that was rough at the end, but did a lot of work: diet, qigong, meditation, reiki, exercise and felt much better. I'm feeling better this morning actually from discussing this all.

I was first diagnosed and had surgery in 2015. We thought we got it all, but a year later my PSA rose and I underwent a similar protocol as you, ( Lupron, radiation, 2 years of casodex) in 2016-17. In 2018 my cancer returned ( PSA increasing) several times and I was able to successfully supress it with Intermittent treatments of Lupron and casodex treatment for three months. The first time my PSA dropped for 14 months, then started to rise and we treated again. The second and third times i got 9 months and then 6 months of supression. Now my PSA has again risen and my cancer has been diagnosed as CRT ( castration resistant cancer) and I am moving from intermittent treatment to continuous treatment of Lupron every three months. My side effects are minimal, with some tiredness and hot flashes mostly in the middle of the night, but certainly tolerable. We are now looking at some new drugs and a possible trial. However, when first diagnosed they thought I might live 2-3 years without surgery. I am now entering my 10th year, and with the new drugs available, we are relatively hopeful for another 5+, or maybe even 10. I will be 70 in three weeks, so this is actually more than I had expected, and grateful for every day. No question that this cancer is complicated and at times a bit debilitating, but there is certainly a life worth living with it as well.

I anticipate that I will experience a reoccurring cancer of prostate in the future . It makes sense that you would go back on Lupron and/or Casadex until it stops working… continue the science experiment until it is time to try something else.
More drugs are coming onto the market… I am watching closely to see how others like us are being treated going forward..

Hey Pwitkin!
Have a Happy 70th Birthday! and make sure to keep posting so we can all CeleBrate Your 80th!!!!!!!! Keep on Going Brothers!
I had 25 EBRT, HIR and 2-1/4 years of Lupron Shots. I temporarily stopped the shots May '23; I am planning to start Lupron again after an 18 month break (tentatively; based upon PSA rise{has stayed at 0.03 down from 20.0}) in an attempt to "thread the needle" of recovering from the side effects of the Lupron and Bull-Fighting with the seeded prostate cancer cells to try to keep them "asleep" and not be stimulated into mutating into the most aggressive prostate cancer cell by using the Lupron for 2-1/4 years and 18 months break cycles, hopefully into my 100's. (Why not stay optimistic!?!)
I know I may be very foolish by having a break from the Lupron rather than just keep it flowing every three months.
A question for the Moderator of this posting site: Is there a central web address for all of the clinical trials in the U.S. related to PC and its metasis?

Jbuuck! Lupron has totally removed the gift of the Marriage Embrace, as well as my former great muscular strength, muscular endurance, and aerobic capacity- I no longer jog marathons which diminished to walking 20 miles, which is now walking 6 miles at 2.75 - 3.0 mph, max. Muscle and joint pain is still present but has not been as delapitating where it had started to interfer with social interactions, not wanting or having the energy to talk or play cards, concentrate on conversations because of energy and focus on trying not to be in pain. From 230 lbs now 263 lbs (and I'm not a prospect as an NFL Linebacker!), brain fog still present (but I have stopped and asked for directions when driving!) Life has changed, but is still a magnificent and marvelous Gift from Our Creator. So I hope all of us who have been diminished in our physical sevice to others will still help others by praying for others and our world. God Bless you all and yours.

Thank you sharing🤗 I am a caregiver: just to make sure I understood
your PSA levels started going up and that is why you are taking a break as well as due to side effects from Lupron? Wonderful optimistic attitude take care and God bless you many more years of life.