Complications with Statins
This may be of use to others taking statin drugs. I had a 5-way CABG in Sep 2015. Shortly after that, my cardiologist prescribed atorvastatin, 10 mg, once per day. My cholesterol numbers were all in the acceptable ranges, and they hadn't changed, and I resisted taking any at all, but I began the regimen. In August 2017, my PCP convinced me I should be on a higher dosage. I did argue against it again because in my post-CABG studies, so many reports, books, etc recommended against almost any at all, but I had had no difficulties with the lower dosage, I deferred to my doctor, and I began to take 40 mg/day. Early in 2018, a number of symptoms became evident: tiredness/fatigue, occasional shortness of breath, occasional lightheadedness, lower and thoracic back pain, itching (mostly from the chest up), frequent headaches (mild), and worst of all, eye difficulties--watery, blurry, darkening of vision, lots of floaters--so much so that reading became uncomfortable and at times difficult. These conditions continued to worsen. I thought about this constantly. I studied my diet, my schedule, my activities, none of which I had changed. I had always taken the drug before bedtime, and it dawned on me finally that since I felt worse in the mornings and better by the end of day, perhaps there was a connection. And since the only change I could see was the statin dosage, I decided to cut it back--at least to 20 mg. And almost immediately, my symptoms lessened. After 4 days, the improvement is dramatic. I almost feel normal again. Furthermore, perhaps rashly, I decided to return to the original 10 mg dosage. I will keep at this for a couple weeks to verify the conclusion, and I will discuss with both my PCP and my cardiologist. But I am convinced, especially with all the literature I've perused, that statins are not for me. I caution all on statins to research this thoroughly. By the way, the higher dosage did lower my cholesterol values, but other vitamin deficiencies are evident in my latest blood panel, and statins may also be the cause of those.
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I appreciated your candor on this topic .... a serious challenge in my experience as well ...
I’m curious as to whether taking statins has proven to actually save lives when taken by an otherwise healthy person vs not taken by an otherwise healthy person? “Otherwise”= a person healthy, active, heathy life style with no other serious medical conditions except high LDL
HomeAgain,
Here's a link to a Mayo site with information on who should be taking statins - https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statins/art-20045772#:~:text=Statins%20are%20drugs%20that%20can,of%20heart%20disease%20and%20stroke.
And, this is a great calculator with which to play around with numbers - https://statindecisionaid.mayoclinic.org/statin/index
For me: age 69, male, never smoked, no AF, no diabetes, treated high blood pressure (140/80 to 115/75), cardiovascular disease (hard answer since only indication is either hypertension or, in my case a high CAC score, so am answering yes), no LV Hypertrophy, SBP 115/75, HDL 50, TC 100, standard dose statin. Current Risk says "Risk for 100 people like you who do take a standard dose statin" is 4 will have heart attack, and 96 will not.
If I change answers to no hypertension, and put in more normal TC of 150, and say no on statin - answer is: 5 people will have heart attacks out of 100.
Then, if I change only TC to 200, the answer is: 13 heart attacks of 100 people. Adding statin back in changes heart attacks to 10.
Taking statin back out and adding in diabetes changes to 20 heart attacks. Adding statin with diabetes is 15 heart attacks.
Perhaps we could all play with this and post our numbers?
I agree, I was given statins for 8 years before I caught on. My legs got so weak I could hardly climb stairs. I researched statins and was amazed at the negative research. I told my doctor I needed to get off the drug, he looked me in the eye and said, "You don't have high colesterol anyway." I wanted to hit him upside the head. I've been off statins for 4 years (new dotor) and my cholesterol is 20 points lower than when I was on statins, my HDL increased by 20 points (diet). Some of the strength in my legs has come back but they will never completely return.
Not on statins and hope to stay that way. Early this year, my PCP asked, as he stated to listen to my lungs and heart, if I would like to be on a statin. This was completely out of the blue with no justification even remotely mentioned. Then recently, as he was reviewing the results of a brain CT scan, he spotted that there is some plaque in my carotid artery. He again suggested statins. When I again declined, he suggested maybe it would be appropriate to get another lipid panel run as the only previous one was from a year ago. (The results came back with my LDL being only slightly elevated.) I am not comfortable with what looks like stretching for any excuse to get me on them. Not going to happen. BTW, I am 77.
hollywood and njhorn,
Did you folks review your status via the calculator?
I'm being prescribed Rosuvastatin (generic CRESTOR). because, even though my cholesterol is now and has been on every blood draw that I have access to view since 2013, within normal ranges. All the numbers. BUT I had some spinal pain that was radiating into my back muscles and my doctor sent me for a Thoracolumbar Spine XRAY and sadly it found several disc degenerations, some arthritis in my cervical, thoracis and lumbar area, and strangely it found Atherosclerotic Calcificiation in my AORTA. Nobody has been able to tell me why that would occur for someone who's never had high cholesterol.
I'm so happy you wrote this post Jackj because my first concern with statins is the suppression of cholesterol which helps with vitamin D synthesizing. I'm nearly 75 and have osteoporosis. I rejected all the requests for osteoporosis drugs because they too suppress a normal body function of the uptaking of old bone, which over time makes peoples bones SEEM to be bigger on DEXA SCANS but the insides of those bones are filled with old brittle bone that was never removed giving a false (IMO) indication of increased bone. And they end up having spontaneous horizontal femur fractures and dentists have started refusing to do certain dental procedures on people taking bisphosphonates becauses they. can easily suffer a jaw bone fracture. INSTEAD I paid nearly $200 a month for (so far ) 2 years to do the OSTEOSTRONG program. Result of my first DEXA 2 years after starting the program with NO DRUGS: 7.2% increase in my spine and 4.4% increase in my hip..and remember, MY increases aren't from new bone wrapped around left behind OLD bone. My increases are all from new bone.
So now I face this. And I CANNOT FIND an answer to the caclium in my aorta. But I'm being told that it could kill me if some of it dislodges and travels to my brain or gets stuck in my heart blocking a valve or causes a critical stomach bleed.
I also had an echocardiogram a few months ago and because I've read that echocardiogram is one of the procedures that often finds arterial plaques. So why it didn't find it is a mystery to me.
I'm complaining about the statin request. my doc ordered only 5mg of Rosuvastatin but honestly, I'm never comfortable with man made chemicals that suppress a bodily function. My understanding is statins prevent cholesterol production by the liver. And as you've noticed Jack, it seems to be messing with your ability to process and retain your proper levels of some vitamins.
And I believe you said your cholesterol was also normal when you were prescribed the statins.
I recently read a paper by a cardiologist. The title was something like "Why I try to get other cardiologists to stop prescribing statins. His reasons were several. But he said there is great pressure by pharmaceuticals AND he would always get a letter from his medical insurer (malpractice insurance) SCOLDING him when he DIDN'T prescribe statins when certain symptoms were presented or diagnosis were applicable.
So I'm very very leery about starting them. I am going to request a Coronary calcium scan which uses a special type of X-ray called a CT scan. It takes pictures of your arteries, the vessels that carry blood away from your heart, to check for calcium.
The scan gives you a number called an Agatston score. The lower the score the more mild the situation is. Zero means the test didn’t find any calcium. The higher the number, the more your doctor will likely push for the statins AND in doses corresponding to your number. The higher the Agatston score the greater the dose.
I'm still researching and not sure which way I'll go. Right now I have a 30 day supply of Rhosavastatin (free to Kaiser Sr Advantage members) and it's a 5mg/day dose.
Good luck you all on this thread who are concerned with taking statins. I'm mostly concerned about this side effect: Can create an autoimmune condition in someone who does not naturally have one. And once that happens it doesn't reverse when you stop taking them. It requires IMMUNE SUPPRESSION therapy!
I am following you, girl, because I like how you talk. I resisted statins being pushed on me for two decades now. I had to change doctors because i refused. However, my Chlorestrol actually went high enough, sort of suddenly, that I am on Repatha. Not a statin, but a new drug, so I figure it will kill me although no side effects, yet. I also was diagnosed with osteoporosis for which I have refused meds. Come to find out the Effexor i take can cause that to my doctor’s surprise. Slowly getting off the Effexor.
IMO, and I am not a medical professional, your statement, "...I'm never comfortable with man made chemicals that suppress a bodily function." is potentially dangerous for your health.
One of the marvels of humans is our ability to investigate and solve problems. There are thousands of medical problems solvable by the involvement of modern chemicals and surgeries.
I would urge you to consult with a center of excellence to resolve what might be unwarranted levels of confusion. It would also be very helpful if you would post the links for those you cite so we may all review the material.
These two links should be helpful - the second one discusses the different between the findings of the two types of tests. (Just in case and to be clear, your echocardiogram was not a simple ECG (sometimes called an EKG, right?)
High CAC is not always related to lifestyle, but in many cases, is. If you are concerned, your physician should be able to order a "Stress with Echo Test."
1. https://www.ucsfhealth.org/medical-tests/echocardiogram
2. https://manhattancardiology.com/blog/heart-scan-vs-echocardiogram-which-test-fits-your-heart-health-needs/