Glutathione: What dosage do you use? Where do you get it?

Reduced L-Glutathione is what I use. You can purchase it capsule or in powder form. I was directed for "my issue" (1) 500mg capsule x daily [nebulized] with 3% saline (4ml). If using powder 1/5 of a teaspoon Reduced L-Glutathione 4ml saline 2x daily. I am not a doctor, but this is the regimen. Mix the above, until the reduced L-Glutathione is completely dissolved into the saline before nebulizing. I use a Pari Vios nebulizer, and a session is about 10 minutes.

Do you nebulize without sodium bicarbonate

Yes. I purchase dry saline (already buffered) and use RO water. Medicare and supplemental insurance will not allow the script to be filled for 3.5% saline. Cleanliness and proper storage, will keep you out of trouble. If you plan to mix your own, find a brine calculator.

Hi Nanette! This is so helpful!!! Yes, I read that book but I did not see the capsules....maybe in the back. I have 2 pulmonary docs, one near me and one in the big medical center in town and they both are resisting giving me a script for the glutathione. I have the sodium chloride ordered but they seem to be having trouble finding it. Please tell me how you chose your functional medicine doc and are there others on that team (like Daniel use...herbalist, naturopathic) I have been diagnosed since 2017 and have not progressed without any treatment of the MAC. Treated the Aspergillus(still showed on next bronch) and the bronchiectasis with Brovana(nebulizer) and Arnuity once a day(steroid) I was even improving until this last illness. Then my Ctscan looked a little worse but I was very sick. The MAC morphed into the abscessus, which is much worse and only treatment is daily hospital infusion and another nebulized medication....since I am asymptomatic they are not treating me....lots of Ctscans which I feel will kill me in the end! every 4-6 months. My lifestyle was very similar (my whole adult life) that Daniel recommended in regards to exercise (runner) and very healthy eating. Maybe that is why i have done well. My saturation is always 98-100, low BP, low pulse, good blood count numbers etc. Please let me know if you tried any of the other things Daniel suggested or if you have any suggestions. Thank you so much!!

The dosage of reduced glutathione is 1/5 tsp to 4 ml of saline.

There is a phase 2 trial called ARINA-1 that is on-going. It is an inhaled glutathione mixture. I am beginning the trial next Monday. Hopefully very soon doctors will be able to prescribe this solution to us. If you haven’t considered the trial I would encourage you to search ARINA-1 on this forum and the thread started by Linda Esposito telling about this trial will come up. There is a link that will lead you to the criteria.

While it seems that we might be able to concoct our own mixtures having an approved treatment will benefit the entire bronchiectasis community. Dr. James Chalmers gave a very encouraging talk at the ELF/EMBARC 2023 Bronchiectasis Patient Conference. He indicated that there are some treatments that may be available as early as 2025 that are showing promise of returning patients to normal lung health, but the research cannot happen without our help!

I’m sure none of us have time for one more thing in our lives since the daily grind with this condition takes much time to control and often leaves us tired. I will be driving 10 hours round trip monthly for the next three months to participate in this trial. It is a big commitment but worth it if the result is a treatment that will be covered by insurance and available to us all!

Hi Kathleen,
I found the Glutathione Plus at https://shop.thedrswolfson.com/products/l-glutathione-plus. There are instructions on how to use it. Pricing for 100 capsules is $41.95.
I have never used glutathione but have heard it is very beneficial. Many thanks go out to Nanette for her post which is prompting me to incorporate glutathione into my 7% saline nebbing routine. I hope the above information helps. I have learned more here than anywhere else. We are a great community!