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Iron Depletion in Blood related to COVID?

Posted by stellm @stellm, Jun 11, 2021

Has there been any reports of iron depletion in the blood after receiving the Pfizer vaccine?

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leelaguna | @leelaguna | Dec 26, 2022

I developed Cold Agglutinin Disease shortly after receiving Covid Booster #1.
It may be related. I have since taken Booster #2. Then I came down with Covid. The Anemia caused by CAD plus post-Covid has wiped me out. I recently had a transfusion. I have no energy. Any suggestions?

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3 replies
av8r525 | @av8r525 | Dec 27, 2022
In reply to @leelaguna "I developed Cold Agglutinin Disease shortly after receiving Covid Booster #1. It may be related. I..." + (show)
@leelaguna

I developed Cold Agglutinin Disease shortly after receiving Covid Booster #1.
It may be related. I have since taken Booster #2. Then I came down with Covid. The Anemia caused by CAD plus post-Covid has wiped me out. I recently had a transfusion. I have no energy. Any suggestions?

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Stop taking boosters for starters.

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leelaguna | @leelaguna | Dec 28, 2022

Want to connect.

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Mentor
Lori, Volunteer Mentor | @loribmt | Dec 28, 2022
In reply to @leelaguna "I developed Cold Agglutinin Disease shortly after receiving Covid Booster #1. It may be related. I..." + (show)
@leelaguna

I developed Cold Agglutinin Disease shortly after receiving Covid Booster #1.
It may be related. I have since taken Booster #2. Then I came down with Covid. The Anemia caused by CAD plus post-Covid has wiped me out. I recently had a transfusion. I have no energy. Any suggestions?

Jump to this post

Hi @leelaguna, you’re trying to connect with other members who share your diagnosis of Cold Agglutinin Disease (CAD) This is a rather rare autoimmune condition according to the National Institute of Health. https://rarediseases.info.nih.gov/diseases/6130/cold-agglutinin-disease

I found another member, @hi2l, in our forum who also has CAD along with other comorbidities and has several replies in various groups regarding their treatment. Here are a few of the conversation links to introduce you to @hi2l

-Does it seem like autoimmune diseases are on the rise?
https://connect.mayoclinic.org/comment/643601/

-Raynaud's Syndrome: Anyone want to talk about Raynaud’s?
https://connect.mayoclinic.org/comment/697357/

-MGUS associated with Type I Cryoglobulinemia
https://connect.mayoclinic.org/comment/665531/

Are you being treated with any medications to help with the anemia besides the transfusion?

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pins | @pins | Dec 29, 2022
In reply to @bjoan "Could it be that Drs aren’t reporting this and assuming coincidence? My Drs just tell me..." + (show)
@bjoan

Could it be that Drs aren’t reporting this and assuming coincidence? My Drs just tell me there is no evidence yet to support my concern. Am I able to report myself?
Zero history of gastro issues. Week after my booster extreme gastro and menstrual problems, lasting a year now. Also developed an anemia issue. Something happened, that is not all coincidence. Trying to fins some answers with my doctors.

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Yes you can self report. From what I understand, it would take the Drs 30-45minutes for EACH patient report. I would think this would not be cost effective nor time efficient for a hospital or office based physician to do during office hours/between patient appointments/visits/consults. This cumbersome and Inefficient process may contribute to low reporting to the VAERS system.

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bellaandted1 | @bellaandted1 | Dec 31, 2022
In reply to @stellm "Yes. My husband has never had any history of anemia or low iron. He received the..." + (show)
@stellm

Yes. My husband has never had any history of anemia or low iron. He received the Pfizer vaccine in March. He began feeling more tired over the next two months. He saw his physician and she suspected some type of internal bleeding based on the blood test, He had an upper and lower endoscopy. No internal bleeding was found. They are going to try the camera endoscopy next week. We don't think this is going to reveal anything. His iron, ferritin and red blood cell count is extremely low. The only change in has been receiving the vaccine.

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Same exact thing happened to my 58 year old husband. He was pale and very tired. Passed out at work and finally went to his doctor who did blood work. His hgb was down to 4.6 and he was hospitalized and received 4 units of blood and iron infusion. He was scoped up & down and had a small bowel follow through with nothing showing any source of bleed. A friend told me they heard about someone who had this happen after a Covid vaccine and suggested I look on line. I feel this is too similar to be a coincidence. He never had issues with his blood work prior to this event. He now is on iron supplement and has a complete blood count every 3 months since he stabilized.

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2 replies
cleanxguy | @cleanxguy | Dec 31, 2022
In reply to @bellaandted1 "Same exact thing happened to my 58 year old husband. He was pale and very tired...." + (show)
@bellaandted1

Same exact thing happened to my 58 year old husband. He was pale and very tired. Passed out at work and finally went to his doctor who did blood work. His hgb was down to 4.6 and he was hospitalized and received 4 units of blood and iron infusion. He was scoped up & down and had a small bowel follow through with nothing showing any source of bleed. A friend told me they heard about someone who had this happen after a Covid vaccine and suggested I look on line. I feel this is too similar to be a coincidence. He never had issues with his blood work prior to this event. He now is on iron supplement and has a complete blood count every 3 months since he stabilized.

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Curious, what did your doctor suggest moving forward? Just continue with supplements?

We are experiencing similar issues as well and currently in the hospital. They’re just monitoring the HGB and already gave two units of blood last few days.

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missjude | @missjude | Jan 3, 2023
In reply to @sueinmn "Good afternoon and welcome to Mayo Connect. We are a community of people living with a..." + (show)
@sueinmn

Good afternoon and welcome to Mayo Connect. We are a community of people living with a wide variety of conditions and diseases, trying to live our best lives, and to help each other along the way by sharing our experiences. We are not medical professionals, and cannot give medical advice, but we can tell you what has worked for us, point you to resources, and help you to be and informed consumer and your own best advocate with your care providers.

Can you tell us a little more about what led you to ask this question? Do you have a history of anemia or another blood disorder?
Sue

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After receiving the Pfizer vaccine boosters, I have had low iron. I have never had low iron in my life and I am 58 years old.

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1 reply
justinesmith | @justinesmith | Jan 3, 2023

I have been reading this and would like to share my experience. I have always been on the low side of normal on the hemoglobin. This last year my ferritin went down to 22. I attributed it to one of the following: diet, thyroid surgery (possible blood loss) but the doctor did a complete work up and also found high white blood cells. I have been having blood counts every three months, eating chicken liver once a week, beef once a week and taking iron pills. My ferritin went up to 40 but the hemoglobin remained a bit low. I had the full iron panel and it was normal. I also have had the pfiezer vaccine and boosters but no covid. The doctor was going to suggest the colonoscopy and upper gi if the levels didn't improve but they did improve after about 6 months. However, now I have been diagnosed with stage 0 of CLL which is a slow growing, chronic leukemia. This was revealed in the blood tests.
My husband used to give blood regularly and he became anemic and thinks it was because he was giving blood so often. He also thought that with getting older he had to stop. He was rejected due to getting anemic. His levels are still a bit low.
I suggest getting the full CBC and the differential blood test which looks more closely at the lab results. Give it time to get the iron levels up if doing it with diet and supplements. Also I read that waiting 30 minutes after an iron rich meal to drink coffee or tea is a good idea since the coffee or tea can interfere with iron absorption.

REPLY
6 replies
missjude | @missjude | Jan 4, 2023
In reply to @justinesmith "I have been reading this and would like to share my experience. I have always been..." + (show)
@justinesmith

I have been reading this and would like to share my experience. I have always been on the low side of normal on the hemoglobin. This last year my ferritin went down to 22. I attributed it to one of the following: diet, thyroid surgery (possible blood loss) but the doctor did a complete work up and also found high white blood cells. I have been having blood counts every three months, eating chicken liver once a week, beef once a week and taking iron pills. My ferritin went up to 40 but the hemoglobin remained a bit low. I had the full iron panel and it was normal. I also have had the pfiezer vaccine and boosters but no covid. The doctor was going to suggest the colonoscopy and upper gi if the levels didn't improve but they did improve after about 6 months. However, now I have been diagnosed with stage 0 of CLL which is a slow growing, chronic leukemia. This was revealed in the blood tests.
My husband used to give blood regularly and he became anemic and thinks it was because he was giving blood so often. He also thought that with getting older he had to stop. He was rejected due to getting anemic. His levels are still a bit low.
I suggest getting the full CBC and the differential blood test which looks more closely at the lab results. Give it time to get the iron levels up if doing it with diet and supplements. Also I read that waiting 30 minutes after an iron rich meal to drink coffee or tea is a good idea since the coffee or tea can interfere with iron absorption.

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Thank you so much for your information. The bloodwork that was done so far was just the routine one and my primary doctor is sending me to a hematologist and a gastroenterologist. I will be careful not to drink coffee too soon.

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