Anyone have nausea with Trintellix?

Posted by nansmith @nansmith, Nov 1, 2017

Anyone have nausea with Trintellix 5mg? How long did it last? Been taking for almost 6 weeks and still have some nausea...will it get worse if I titrate to 10mg? Thanks.

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tink1 | @tink1 | Jan 4, 2022

In reply to @heidi1346 "I had to stop the Trintellix. The constipation was worse than the nausea. Anyone have severe..." + (show)

I have been on just over a month and yes constipation is an issue. Have been trying fibre powder in my drinks.

marjou | @marjou | Jan 4, 2022

In reply to @tink1 "I have been on just over a month and yes constipation is an issue. Have been..." + (show)

Yes nausea and stomach issues which is common side effect on this medication.

rightgirl | @rightgirl | Jan 6, 2022

In reply to @colleenyoung "Hi Tink, Like you, several members have experienced nausea with Trintellix. I'm tagging @frankiep @heidi1346 @kelster69..." + (show)

My nausea while on Trintellix became unbearable. I switched back to Lexepro and it disappeared immediately. Lexepro works well for me. Give it a try.

5148branelly | @5148branelly | Feb 14, 2022

I took Trintellix for about a year, and had nausea and vomiting without any warning. I used the anti-emetic, Zofran, which was great until it no longer worked. The anti-depressant that I'm on now doesn't work as well as Trintellix. Anybody know any anti-emetics that work well with Trintellix ?

clutch | @clutch | Feb 15, 2022

@5148branelly
What OTC medicines have you tried? Ginger tea and chews work with mild nausea. How about The Relief Band that uses a pressure point on the wrist? What Rx medicines have you already tried?

linlou | @linlou | Feb 26, 2022

I’ve been taking Trintellex for almost 5 weeks. Started it at 5mg and up to 10 now. It helps with depression very well but nausea is very bad. Nausea has never been one of my top issues with antidepressants , and I’ve tried them all. I’m very surprised how severe the nausea is and how long it’s lasting not sure if it last I can stay on this . Does any have any similar experience and does it go away . Also I’d like to know the mechanism by which it cause such bad nausea ?

linlou | @linlou | Feb 26, 2022

In reply to @5148branelly "I took Trintellix for about a year, and had nausea and vomiting without any warning. I..." + (show)

I don’t know if any but I’m very curious as to why it causes so much nausea for so long usually side effects disappear . It really to bad because it’s effective otherwise

linlou | @linlou | Feb 26, 2022

In reply to @rightgirl "My nausea while on Trintellix became unbearable. I switched back to Lexepro and it disappeared immediately...." + (show)

I’ve never had nausea with other antidepressants before so this is very strange for me and I like to know why. It would be nice if H . Lundbeck could address this issue . I want to stay on it because I’ve read it’s Neuro protective also.

linlou | @linlou | Feb 26, 2022

Yes, I also have bad nausea after 5 weeks . It works very well otherwise , not sure how long I can tolerate if it doesn’t get better.

clutch | @clutch | Feb 26, 2022

In reply to @linlou "I’ve been taking Trintellex for almost 5 weeks. Started it at 5mg and up to 10..." + (show)

@linlou Id like to know the answer to your question also, regarding nausea. I’m not sure that’s very well understood by anyone, at least I’ve never heard it explained. I had terrible nausea when tapering a benzo, so I can relate. I may can offer some solutions for nausea. What have you tried?