Getting off of Seroquel

Posted by anniegk @anniegk, Jun 8, 2018

I have been on 300 mgs. Seroquel ER for over a year for augmenting my antidepressant which is 45 mgs. Of Mirtazapine. I decided to try and get off of the Seroquel. I was on 300mgs ER (extended release). I titrated down to 250 mg ER for 2 months without too many problems.than i titrated down to 200mgs ER just 5 days ago. My plan is to try to titrate off using ER tablets. My thinking is that perhaps the drug will remove its self from my system more gradually. I have had some nausea and a couple of episodes of diarrhea. I also have a very irregular heart beat and was started on 60 mgs of Propranolol ER (extended release) 4 weeks ago. It seems to be helping my heartbeat. I have wondered if the nausea and light headness is from the Propranolol, a Beta Blocker, or the dose reduction of the Seroquel. I also wonder if the way iam titrating the Seroquel is safe. My doctor says it will only take a couple of weeks...I think that is too fast of a taper after being on a drug for over a year. What do you think?

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@mayo337xxx
Whoa 2 whole weeks & cold turkey, what did you expect to happen?
How long have you been taking Seroquil and what was your dosage and what were your taper dosages? It’s very obvious that you tapered much much much too quickly I think you know that
Jake

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@mcshibe

Hi everybody. I'm glad I've found this thread on the internet, have been reading the first half of it so far, will continue to catch up another time. I figured I'd provide my own experience and feedback on the med.

I've been on seroquel for 3 and a half years by now, mostly because of restlessness (supposedly triggered and fueled by anxiety and stress).
My initial dose was 100mg, to take after dinner. The doctor also prescribed me duloxetine to take once waking up, in order for me to feel less of a zombie.
For more than a year now I've only been on seroquel 25mg, although I still resort to 50mg when I'm particularly anxious and can't fall asleep with 25mg.
I haven't really consulted my psych in the last 2 years, can't afford it, so I've been doing this all on my own.
Every once in a while I try to sleep without taking any seroquel and it never works, like last night. It's completely shattering for me.
I really want to get off of it completely as it makes me feel sluggish and unproductive and I don't even like my body as my weight is 10-14 kilos more than what it used to be.
I'm currently cutting 100mg pills into four to get a 25mg dose. I've read in this thread's earliest pages that 25mg pills are also commercialized and it looks like it in my country too, so I guess I should buy those and start cutting them into two pieces to lower the dosage further.

When I switch from 25mg to 50mg, I suffer constipation (and hemorrhoids too sometimes) the first days after that.
When trying to get back to 25mg, I may also be unable to put myself asleep at first attempt, but it's never particularly complicated. This is probably due to the fact that I've been avoiding taking 50mg unless I'm being under particularly high levels of stress.
Conversely, when I lower the dosage, I may get fewer hours of sleep the first nights, than the average 9-10 hours I get on a steady prolongued regime of 25mg.

I still think 9-10 hours is too much, especially considering that once awoken I feel sluggish, hence why I wanna further lower the dosage.
My libido is obviously below average but on 25mg I can still manage.

Also, I don't quite understand this but it seems that I feel very cold during my sleep when I'm on seroquel. I used to think it was just me becoming unusually sensitive to cold in these last years but it's most probably not the case as last night (while skipping on the med) I tried sleeping with the same pajamas and blankets as regularly and I was just melting, like normal people would (for example my brother who sleeps in the same room). But the thing is that it's not just my impression, as if I don't cover myself that much, I get headache, throatache and earrache the day after. I also usually know this in advance as I get nightmares when I'm feeling cold during my sleep. Unfortunately, I'm generally unable to wake up in the midst of the night due to the effect of the med, even if I'm having vivid nightmares.
I'd need to spend more nights off of the med to really conclude that it's the med's fault with certainty but I can't deprive myself of sleep that often.

I will be following the thread from now on and post updates whenever there will be any

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You’re not alone !!
Have u ever slept walked on seroquel ?
Every time I’ve tried to get off the crap and go below 200 mg I sleep walk. This time I’ve only done twice ( drank hydrogen peroxide one night and shampoo another )
I too seem to be on the cold side

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@mayo337xxx
The best way off your medication is to do it slowly, extremely slowly infinitesimally slowly if necessary.
The major factors how to taper off Seroquel are how high your dose was and how long you have been taking the medication.
Jake

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@jakedduck1

@mayo337xxx
Whoa 2 whole weeks & cold turkey, what did you expect to happen?
How long have you been taking Seroquil and what was your dosage and what were your taper dosages? It’s very obvious that you tapered much much much too quickly I think you know that
Jake

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I know but if you sleep walk while weaning and drink shampoo and hydrogen peroxide wile on these walls you’d try cold turkey too
Cold turkey doesn’t work ( duh ) 😂I know
I’m desperate to get this poison out of me
Thanks for sharing

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@mayo337xxx

I know but if you sleep walk while weaning and drink shampoo and hydrogen peroxide wile on these walls you’d try cold turkey too
Cold turkey doesn’t work ( duh ) 😂I know
I’m desperate to get this poison out of me
Thanks for sharing

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@mayo337xxx
Are you married live with someone or do you live alone?
Jake

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@erikas

@mayo337xxx Welcome to Mayo Clinic Connect. It must be a challenge to not be able to sleep after successfully tapering off Seroquel. Sleep is so important for healthy living. You'll notice that I've moved your question to an existing discussion. I did this so that you could connect with members like, @chrisjc @vickimurray @helenfrances and @mcshibe, who may have some thoughts on sleep after stopping Seroquel.

@mayo337xxx How long were you on Seroquel? What things have you done since weaning off Seroquel to help improve sleep?

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200 mg for sleep
Valium helped bit 2 days after that script was gone back to torment
I’ve been up over most of the last 4 weeks
Maybe 5 hours sleep til last night
I took a 50mg slept pretty good
Idk the best way to beat this insidious drug

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@jakedduck1

@mayo337xxx
The best way off your medication is to do it slowly, extremely slowly infinitesimally slowly if necessary.
The major factors how to taper off Seroquel are how high your dose was and how long you have been taking the medication.
Jake

Jump to this post

I’ve tapered from 200 to 50 w a couple hours sleep over about a month
I ate a 50 mg piece last night after 9 days w nothing. Slept pretty good
Thanks

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In reply to @mayo337xxx "Married" + (show)
@mayo337xxx

@mayo337xxx
Well it’s good that you’re married at least your wife can help you out. Can she hide,lock up some of the various items you shouldn’t be drinking?
Are you willing to start your taper over again?
Have you gone to your physician and asked him about retapering off this drug?
My guess is you’ll have tapered too quickly and probably had side effects and if you do I would increase it some and then decrease it at a slower rate. These medications can be tapered off of withdrawal free if they’re done slowly. Your brain needs time to adjust.
I hope you’re not taking 200 mg a day for sleep. Are you aware this medication can cause diabetes 2? It is not recommended by the manufacturer to taken for sleep problems?
Jake

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Hi, My name is Annie and Im new here , my doctor wants ne to start sequal. What exactly is it used for and what are the side effects. Any advice would be nuce. Thank you

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