Adrenaline spikes: Med detective needed, award given

Posted by sierrawoods @sierrawoods, Feb 20, 2018

I'm desperate for help. If I was rich, I'd pay a million $ to get answers. It's hard to summarize: I am a 59 yr old woman. 8 yrs ago I started having what feels like strong adrenaline rushes during the night and especially in the early morning. They disrupt my sleep making me severely sleep deprived. It used to happen a few times a month but in the last year, has been happening daily. This is not as simple as anxiety. My life is not particularly stressful compared to years ago and I've always handled stress well. Physical symptoms come first, then anxiety from adrenaline comes after. On rare days, If I sleep through the night, I wake with excess adrenaline and will be hyper the whole day and evening. Sometimes, I will have a severe "crash" in the afternoon with all kinds of symptoms that have me couch-bound. I take a tiny dose of Amitriptyline (10 mg) before bed to help with sleep, but it's obviously not working well enough. I am on Synthroid for non-Hashimoto's Hypothyroidism since 1996. Despite being 59 yrs old, I am not yet officially in menopause (last period was May 2017). TSH, fT4, fT3 are normal. Urine catecholamines (epinephrine & norepinephrine) are normal (although that does not necessarily reflect what is in the brain). Plasma ACTH is normal. I've tested negative for autoimmune disorders. Cortisol was high a few years ago (34.3 mcg/dL) but it's currently high-normal. DHEAS normal. Accompanying the start of this was phantosmia and occasional RLS. My diet is excellent, including a few good supplements. Until last yr when it started happening daily, I was exercising 6 days/wk. I cannot tolerate it any more - any exercise beyond mild cardio/aerobic causes an increase in symptoms. I meditate and have tried all kinds of herbal teas. I've experimented with different possible solutions, to no avail. I'm a voracious researcher (only legit sites) and still cannot figure this out. I'm normally a positive, active, happy person who loves to help others but this is ruining my life. I cannot make any plans, cannot get my work done, cannot even visit friends. I had to stop my volunteer work with children. šŸ™ I'm starting to become depressed and hopeless. I've been to a total of about 9 doctors about this problem and they just shrug their shoulders and send me hope with more disappointment. The only help offered was an addictive prescription for benzos but I refuse to be treated for something without knowing the cause. Ideas: an atypical tumor on my pituitary or adrenal glands? Maybe, but I can't get a doctor to order the necessary MRIs. Perhaps not endocrine but a sleep disorder? High A.M. adrenaline is typical for sleep apnea but it should not cause these severe symptoms, and I really do not think I have sleep apnea (I don't have other symptoms). A neurological disorder? Maybe, but I can't get a doctor to order an MRI of my brain to make sure my pituitary gland is okay. If you've gotten through this far and you have any thoughts, please chime in. If your idea leads to a proper diagnosis and I get well (or treated properly) I will be your slave for life šŸ˜‰ Okay, seriously. I'm not in a good place right now.

Interested in more discussions like this? Go to the Diabetes & Endocrine System Support Group.

It could be--we are all different and have different reactions. I usually don't get much of a warning before it happens to me; I read that it happens to people who have had a lot of lows, sometimes no warning at all. That is no fun, I can assure you! I hope you had a great Christmas, and have a very Happy New Year! Good Health to you my friend!

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There is a condition called hypoglycemia unawareness. It is having low blood sugars with little or no symptoms. It is a complication of diabetes. It can be dangerous because there isnā€™t much warning to treat it.You can end up in an emergency situation, helpless and at the mercy of others to catch it and hopefully intervene. In my case it was during the years of type 1 diabetes when blood sugar was out of control and insulin wasnā€™t adjusted properly.

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@chocolate5lover

It could be--we are all different and have different reactions. I usually don't get much of a warning before it happens to me; I read that it happens to people who have had a lot of lows, sometimes no warning at all. That is no fun, I can assure you! I hope you had a great Christmas, and have a very Happy New Year! Good Health to you my friend!

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@chocolate5lover I hope you had a great Christmas also, and that the new year will be a healthy and joyous one for you.
JK

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@sierrawoods Not sure if you were able to get the help you needed in 2018, but I have had similar issues this past year. I have hypothyroidism, endometriosis, and. Psoriatic Arthritis. I am on Celebrex for the arthritis, both synthetic and natural estrogen and progesterone (because I am in surgical menopause due to the endometriosis), and I take Synthroid as well.

I discovered if I take my Synthroid at night, it makes a huge difference to the adrenaline hot flashes! I also use a small dose of progesterone cream rubbed into the inside of my wrists before bed, which also makes a big difference with my sleep. I was on 100 mcg of Synthroid when my symptoms started, and then I upped that to 112 mcg, and Adrenaline filled hot flashes mostly disappeared for 3 months. I started having hot flashes combined with adrenaline rushes again this past December, so I have recently increased my dose to 125 mcg, and the symptoms have disappeared again.

My TSH was a 2 when having issues, and was around .5 or lower when symptoms disappeared. My doctor was hesitant to increase my Synthroid each time, but I insisted that I canā€™t live with night upon night of broken sleep, and a little more Synthroid seemed like a simple fix for a complex problem!

Just wanted to share, in case you are still suffering, and still monitoring this thread! Good luck! Keep advocating for yourself!! And thanks for your original post. My doctor told me if had never heard of these symptoms before, so itā€™s good to know Iā€™m not the only one in the world dealing with this!

Take care šŸ™‚

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@libjen

@sierrawoods Not sure if you were able to get the help you needed in 2018, but I have had similar issues this past year. I have hypothyroidism, endometriosis, and. Psoriatic Arthritis. I am on Celebrex for the arthritis, both synthetic and natural estrogen and progesterone (because I am in surgical menopause due to the endometriosis), and I take Synthroid as well.

I discovered if I take my Synthroid at night, it makes a huge difference to the adrenaline hot flashes! I also use a small dose of progesterone cream rubbed into the inside of my wrists before bed, which also makes a big difference with my sleep. I was on 100 mcg of Synthroid when my symptoms started, and then I upped that to 112 mcg, and Adrenaline filled hot flashes mostly disappeared for 3 months. I started having hot flashes combined with adrenaline rushes again this past December, so I have recently increased my dose to 125 mcg, and the symptoms have disappeared again.

My TSH was a 2 when having issues, and was around .5 or lower when symptoms disappeared. My doctor was hesitant to increase my Synthroid each time, but I insisted that I canā€™t live with night upon night of broken sleep, and a little more Synthroid seemed like a simple fix for a complex problem!

Just wanted to share, in case you are still suffering, and still monitoring this thread! Good luck! Keep advocating for yourself!! And thanks for your original post. My doctor told me if had never heard of these symptoms before, so itā€™s good to know Iā€™m not the only one in the world dealing with this!

Take care šŸ™‚

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@libjen I am not having a problem with my levothyroxine, but it's good to know that if necessary it can be taken in the evening. It doesn't interfere with your sleep?
JK

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@contentandwell I think you and @libjen are posting about 2 different meds. You are posting about Omeprazole. @libjen and @sierrawoods are posting about Synthroid.

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@cehunt57

@contentandwell I think you and @libjen are posting about 2 different meds. You are posting about Omeprazole. @libjen and @sierrawoods are posting about Synthroid.

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@cehunt57 Oops, you are right. I will correct that post to say levothyroxine.
JK

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@contentandwell

@libjen I am not having a problem with my levothyroxine, but it's good to know that if necessary it can be taken in the evening. It doesn't interfere with your sleep?
JK

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No, it actually helps me sleep through the night as it seems to control the kind of adrenaline hot flashes that @sierrawoods originally posted about. I checked with my pharmacist, and she said it can be taken at night. I just need to make sure it is at least 2 hours after Iā€™ve had anything to eat (so it prevents snacking in the evening too!) Luckily, I have the kind of work schedule that allows me to have an early dinner to accommodate taking my Synthroid on as empty a stomach as possible before I go to bed šŸ™‚

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Hello, I have been searching for moths to figure out what is happening to me. And I found this post. I am experiencing the exact same thing. I couldnā€™t quite put an explanation to the sensations I get. It all began May 2018 for me when I had my right thyroid lobe removed. They did not put me on any thyroid meds as they say my thyroid tests read normal. Soon after June 2018 I began what I like to call a living nightmare of events. All day and all night I have these adrenaline surges similar to the feeling of looking over the top of a very high building. They scare the crap out of me. They happen all day, and all night. I hardly sleep as they are so strong they wake me up and I have trouble falling asleep as they happen around every 18-25 seconds non stop. Along with this I also began having major heart palpitations which have been diagnosed as SVT. I have had spells of extreme light headed and I have also fainted. All which my dr kept telling me was anxiety. I am not having anxiety. Itā€™s upsetting me. I have gained 25 pounds (Iā€™ve never weighed over 120 in my life. I am 39 years old, not in pre menopause (I have a 2 year old) I am extremely tired all the time. I used to be extremely active, now I am basically house bound. The easiest tasks drain me. I am so frustrated and when I explained to drs what is happening they shrug it off like nothing is wrong. I canā€™t live like this much longer, and am so desperate for answers. I can no longer drive due to the occasional fainting. Please if you have any further information please share.,Iā€™ll be following your post. Good luck to you as well, I understand your nightmare.

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Hi @mittzyvon and welcome to Connect! It must be horrible dealing with these symptoms, and not getting any help from the physicians you go to.

I wanted to introduce you to @sierrawoods @libjen @contentandwell @gailb @jigglejaws94 and @lmherman as they have experienced something similar or have experienced a mystery diagnosis and may be able to help and support you as you search for answers.

Back to you @mittzyvon have you been given any form of treatment at this time?

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