Has Anyone Tried the New drug Ibsrela for IBS-C ?

@bb03
Thank you for this explanation. I have never heard of this device and my gastro physician never suggested it. I will pursue it.

I am so grateful to you. I sent information and the ordering website to my gastroenterologist.

He is now in touch with a company and will be submitting an order for a start kit and then a refill kit.

It's worth a try and thank you again so much for mentioning it as response to my post.

I’ve got Parkinson’s disease with IBSc, Gastroparesis, and a lot of other Issues. I’m on a plant-based diet low FOD nap,.
I tried and failed Amitiza, Linzess, Motegrity, primarily due to side effects Of extreme cramping bloating, And abdominal pain. I started ibsrela A week ago and I’ve been taking it just before my first bite. I typically sit upright for three or four hours after any meal before I lie down. Almost immediately, I get severely bloated with intense upper gastrointestinal discomfort.
It’s probably the gastroparesis and the Ibsrela Doesn’t seem to be working with it. And also taking MiraLAX, but cut back after I started the ibsrela. It hasn’t helps with respect to my constipation, and I have not had a bowel movement spontaneously and quite some time. Had to resort to daily or almost daily enemas. about all the ibsrela is to increase my farting. Perhaps that’s a start But the intense epigastric bloating Every night at bedtime doesn’t seem to be worth it.

I tried Amtizia, Linzess (that made me sick) and Isbrela.. none worked..so I tried Trulance and it works quite well.. sometimes I have to use MiraLAX..and or prune juice and once in a while (every year or so 2 Bisacodyl's) I take Trulance every AM and if I start to slow down MiraLax in the PM..I like to go every day.. quite phobic about it actually!! I also take 2 VSL3 Probiotics every AM .. they are expensive and need to be refrigerated.. but worth it..Amazon ships them in a large box with some kind of ice pack..prayers for you!!

@standinginfaith Yes !! I tried all of those too and got no relief. But Trulance is my secret for overcoming constipation. I take one every night with two stool softners and two Senna. Sometimes I skip the Senna. In the AM, I put a teaspoon of Miralax in my coffee, unless I feel ok without it. I also take gummy probiotics and Vit. D too. It takes a lot of pills and stuff to get rid of constipation and I hope this will continue as effective as it is now. It took a lot to find this recipe !

@phxbarb Oh isn't it wonderful when something works!! Soo happy for you!! God bless!!

I will be starting IBSrela soon, but meanwhile I need more help to treat my recurring episodes of terrible cramping & diarrhea for hours, now lasting for 2-3 days every week or two. Various diagnoses. What do you take for attacks of IBS diarrhea or colitis-associated diverticular disease? I have bentyl and levsin, each of which helps the pain, as does pepto or immodium. But is that all there is??

@berkhills - having hours of terrible cramping and diarrhea sounds awful. While you await your isbrela, it does make sense to try to understand and treat your cramping and diarrhea better.

Fellow members @standinginfaith @phxbarb @coho222 @tekbek may have some thoughts on what helps them with attacks of IBS dirrhea for hours and cramping.

What has your doctor directed you to do next, berkhills?

Hello. After 3.5 years of supposed G.I. pain, and 7 G.I. docs later, turns out it was MALS. Surgery took care of that but I still had bad constipation and now, post MALS surgery, bad internal gas. My vascular surgeon referred me to #8 G.I. doc thinking I would have a better time, and indeed I did. My goal was to solve constipation and gas without pharmaceuticals as I've tried them all w/o any success. He asked if I've ever tried the OTC Berberine. I hadn't and it has now been 3 months taking 500mg of Berbetine 2x/day AND maintaining a strict low FODMOP diet. I've NEVER in my life, pooped so much. And normal poops as well. The low FODMOP diet helps with keeping gas down which I will do anything for. I still have stomach pain at times and gas, but I am light-years ahead of where I was for sooooo long.

Beth

@bkatz43 Dear Beth, I was really interested in Berberine until I heard that a common side effect is constipation and I battle that enough as it is. But you said it *helped* with yours?