Do you take magnesium L threonate? Pros and Cons?

@seekingserotonin
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I've been taking magnesium L-threonate for two months now, and I'm sleeping better, a well-known seizure trigger for me. As for cognitive improvements, it's still early to say. Back in February, I switched manufacturers on one of my medications, which brought a nice decrease in seizures. I've noticed some improvement in my cognitive function, but I honestly can't tell if it's from the magnesium, the seizure reduction, or both.
What kind of cognitive challenges are you currently facing?
Chris

@minajo
Hi Lisa's mom!
As I've shared, I've been taking it for two months now and haven't observed a direct link between it and any change in my seizure pattern. As far as I know, magnesium L-threonate hasn't specifically been studied for seizure reduction; the research so far is mostly about cognition and sleep.
What I have clearly noticed is better sleep quality, which I track through my watch. How is Lisa's sleep quality with Lamictal?
@pb50 @arichards3 @absentsenior — you've been taking magnesium L-threonate longer, so have you noticed any benefits connected to your seizure pattern?
Chris

@santosha - I am happy to report that I am not a seizure patient. I am focused on cognitive and sleep influence...

Hello
Lisa has always had issues with sleep, being autistic, quite common
The onset at 32 of seizures and different aeds, sleep rx, supplements etc hasn't made much of a difference
The lamictal certainly hasn't helped, she goes to sleep late, wakes couple times, awake by 6am
Now trying to decide whether to take Seroquel down anymore, was 175,split am&pm, dropped am from 75 to 50 ,just caused behavior issues but corrected qt prolongation
Also starting estrogen ( she's 50, menopause ?) changed thyroid, still gets impacted after part of colon removed late 2024 so sometimes gi issues keep her awake
So, there are so many systems not functioning correctly and adding another supplement not always easy since she's nonverbal.. usually I try it first, as I did with magnesium glycinate, which didn't help my sleep at all!
Thanks for any guidance!

Hi @pb50
Thanks for clarifying that.
I'm glad to hear the pathology after your surgery in May came back with clean nodes and margins. Wishing you a smooth recovery! 🙌
Chris

@lisalucier no, I did not read any studies and aware of none. I take it because I have had a rough handful of years w seizures, causing more damage. I chose l threonate because it is the only mag to cross the blood brain barrier. my were neuros became aware and approve.
it helps w sleep and I definitely poop more than i thought i could, prior. I hope for the positive effects on cognition and memory, too. but can not be sure.
weirdly, my Physical Therapist was really excited about it, too and also recommended Lion's Mane for overall brain health. I started that, too and later informed neuros and they are fine with it, too.
I am sorry I could not be more helpful.
I do not think there are any studies. it is just something I came across.

@minajo
Hi Lisa's mom!
What you're carrying right now is so much — Lisa's sleep struggles, the medication balancing act, the recent surgery still affecting her, menopause starting on top of it all, and doing so much of this guesswork yourself since she can't tell you how she's feeling. That's an enormous amount of love and effort you're putting in, and you're doing an incredible job navigating all of this for her. 💜
I want to share a bit of my own experience, in case it helps. Lamictal was my first AED, and I had insomnia with it too — a common side effect — and eventually had to switch medications. That said, every person is different; I know others who've done really well on it with no sleep issues at all.
Something a doctor once told me stuck with me: try one thing at a time, so you can really tell whether it's working. When several changes — medications, supplements — happen all at once, it becomes so hard to untangle what's actually helping and what might be making things harder.
I'm curious — has Lisa's sleep gotten worse around any of these changes: starting Lamictal, the Seroquel adjustment, or the estrogen? Even a small pattern might point you somewhere useful.
Sending you much strength and my best vibes. 🙌
Chris