My TC journey: Taxotere (docetaxel) & Cytoxan (cyclophosphamide)

Posted by srobinet @srobinet, Apr 8 7:28pm

I have 4 rounds of TC. How likely am I to get stomach cramps? I am not worried about the nausea since I have meds for that. My mom did one round of Chemo and I believe stopped because of the stomach cramps. What is the best way to deal with them? As previously stated in another thread I do not like water very much. I read that juice counts but that Apple and Grape juice should be watered down? Why is that? I know I have to stay hydrated and I will flavor my water. Keep me in your thoughts that I can make it through this. I do realize I'm blessed that I do not have to take the Red Devil chemo and that my situation could be so much worse. It's still scary though.

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Profile picture for srobinet @srobinet

@missycat I totally understand how you feel. Yes it feels like Wheel of Fortune spin the wheel each infusion and see what side effects you get . They are different each time and seem to last longer. I finished my 3rd infusion 5/21 so just one left.

I wanted to reduce the strength of this 3rd infusion but my oncologist did not agree. I trust him and because of the grade 3 and Triple Negative we kept it the same. I will finish the last round on 6/11 and hope to finally be done with this God willing. Hang in there you can do it . Take care.

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Thank you. Sounds like we're on the same boat. Im TNBC, grade 3, with an oncotype dx 51%. I'll be done around the same time as you. I think radiation therapy is next step, not sure yet. Can't wait for 2026 to be over! Prayers to us all!

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Profile picture for srobinet @srobinet

I am doing a TC chemo regimen which requires 4 rounds. I had Triple Negative cancer caught early no lymp node involvement and clean margins. The tumor was aggressive but small. Due to my family history and the tumor grade my Oncologist felt it would benefit me to do the chemo. I have finished round 2 on May 9. The sides and part of the top of my hands are red and tight feeling. I have kinda the same thing happening on my feet. They are sore and slightly have a falling asleep feeling not for long it goes away.

I need suggestion for how to manage this it is very tender and uncomfortable. This happened to the bottom of my heels after the first round of Chemo but it got better and went away. This is not getting better. I am due for my 3rd infusion on 5/21. Since I have no lymph node involvement and clean margins and had a bilateral mastectomy I am wondering if all of this damage is really worth the extra benefit I would get from the remaining chemo. If it is this way after the 3rd infusion I don't know if I can do this. On a positive note my mouth ulcers were not that bad this time only to be replaced by this hand/foot stuff.

If I stop after this next round and then the cancer came back I would feel horrible that I quit. This just seems like it's getting harder and harder each time. I'm over this and just want to feel good again.
As mentioned before I know I am blessed and that this is only 4 rounds. It doesn't make it any easier though. My heart goes out to everyone who is going through this.

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I thankfully do not have to do radiation. I had a bilateral mastectomy due to family history.

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Profile picture for missycat @missycat

Omg, I could've written your post. Exact same diagnosis. My 3rd round is May 27th and I don't know if I can handle it. I've had a rash on arms and legs that is driving me crazy! My oncologist said every infusion will result in a different reaction. What if my next infusion makes the rash worse! I know that I have to finish my 4 rounds for the bigger picture, but dam!!! I too just want to feel normal.

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@missycat I did my 3rd infusion 8 days ago and unfortunately I had the same reaction with the hands and feet. They loaded me up on steroids every day hoping to prevent this from happening again. My feet are peeling and are sore. This drug burns your skin from the inside out or appears to like a really bad sunburn. I am supposed to have my last infusion on 6/11/26 but the doctor's physician assistant told me today that it could get cancelled or they might only give me the one drug that doesn't cause the skin issues. It has been a journey these last few months and I will be so glad to be done and try to get back to feeling normal again.

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I have had 3 full infusions of the TC regimen. I started experiencing a bad skin reaction on my hands/feet after the 1st infusion. My oncologist did not want to lower the strength and just prescribed more steroids every day. Each infusion the condition of my skin gets worse. My hands are red/stiff feeling and the skin is peeling. The same goes for my feet but to a lesser degree. It has been 2.5 weeks since the third infusion and it is not better. I am not willing to do the fourth infusion with the Taxotere due to these side effects. I am going to finish the 2nd drug of the 4th infusion.

Has anyone had this problem with their hands/feet? I have read that this continue to happen even weeks after stopping chemo. How long will it take for these symptoms to go away. I am using a thick moisture cream to prevent the skin cracking.

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Profile picture for srobinet @srobinet

I have had 3 full infusions of the TC regimen. I started experiencing a bad skin reaction on my hands/feet after the 1st infusion. My oncologist did not want to lower the strength and just prescribed more steroids every day. Each infusion the condition of my skin gets worse. My hands are red/stiff feeling and the skin is peeling. The same goes for my feet but to a lesser degree. It has been 2.5 weeks since the third infusion and it is not better. I am not willing to do the fourth infusion with the Taxotere due to these side effects. I am going to finish the 2nd drug of the 4th infusion.

Has anyone had this problem with their hands/feet? I have read that this continue to happen even weeks after stopping chemo. How long will it take for these symptoms to go away. I am using a thick moisture cream to prevent the skin cracking.

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Some of you may have read my other posts about my skin reaction to the Taxotere. My 4th and final infusion is scheduled for later this morning. I have had such a bad reaction to the Taxotere which gets worse with every infusion that I am not sure I am going to finish it. My hands stay red and with skin peeling despite being on steroids before and after the last infusion. I ended up on a Medrol dose pack and it still did not help. Only now 3 weeks later has the redness and stiffness decreased a little. I can't take hot showers can only tolerate lukewarm water on my hands or it stings/burns.

My thoughts are that I am willing to take the Taxotere but at a reduced strength hoping for less of a reaction. I do not want permanent skin damage from this drug. I have gotten 3 full strength rounds. My tumor was small 1.2 cm with clear margins and lymph nodes, but tumor grade was a 3. CK-67 score was around 30-31 as far as I can remember and I had a bilateral mastectomy. I am also scared not to do the full strength will it matter that much?

Opinions anyone or advice?

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I am finishing 4 rounds of TC chemo later today. How long did it take for everyone's taste buds to recover and about how long before hair starts to grow back?

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Profile picture for srobinet @srobinet

I am finishing 4 rounds of TC chemo later today. How long did it take for everyone's taste buds to recover and about how long before hair starts to grow back?

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I had 11 rounds of Taxol. Two months after my last infusion, peach fuzz started. I'm 7 months out from last infusion and I almost need a haircut.

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Profile picture for srobinet @srobinet

Some of you may have read my other posts about my skin reaction to the Taxotere. My 4th and final infusion is scheduled for later this morning. I have had such a bad reaction to the Taxotere which gets worse with every infusion that I am not sure I am going to finish it. My hands stay red and with skin peeling despite being on steroids before and after the last infusion. I ended up on a Medrol dose pack and it still did not help. Only now 3 weeks later has the redness and stiffness decreased a little. I can't take hot showers can only tolerate lukewarm water on my hands or it stings/burns.

My thoughts are that I am willing to take the Taxotere but at a reduced strength hoping for less of a reaction. I do not want permanent skin damage from this drug. I have gotten 3 full strength rounds. My tumor was small 1.2 cm with clear margins and lymph nodes, but tumor grade was a 3. CK-67 score was around 30-31 as far as I can remember and I had a bilateral mastectomy. I am also scared not to do the full strength will it matter that much?

Opinions anyone or advice?

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How long do you need to take Taxotere after your last infusion?

My chemo treatment was TC however after chemo ended, I waited 1 yr before starting 2nd treatment with Tamoxifen. My body and mind was so weak, I chose to recover first, physically before starting the next treatment.
I worked closely with my Mayo team on what I could or could not tolerate. They are very supportive.

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Profile picture for Arvind Natarajan @malebreastcancer47

How long do you need to take Taxotere after your last infusion?

My chemo treatment was TC however after chemo ended, I waited 1 yr before starting 2nd treatment with Tamoxifen. My body and mind was so weak, I chose to recover first, physically before starting the next treatment.
I worked closely with my Mayo team on what I could or could not tolerate. They are very supportive.

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@malebreastcancer47 I do not have to take any additional treatment . My receptors were all negative and will not respond to any of the usual drugs given for maintenance . That is my understanding at least.

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Profile picture for srobinet @srobinet

I am finishing 4 rounds of TC chemo later today. How long did it take for everyone's taste buds to recover and about how long before hair starts to grow back?

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I started 1st TC in early July 2025, last one in early September. My Oncologist also went through same chemo regime, and she recommended Biotin supplements and hair oil (I used a blended hair serum with rosemary oil and peppermint oil). My hair grew back with a vengeance! I had stick straight hair, kind of blended gray color with a medium blond base. It came in white and super curly. Chemo curl. I stopped wearing wigs and caps around mid November, but the real growth was in around January. I've had 3 haircuts since my initial buzz cut when hair started falling out. It's still in a pixy kind of style, but the curl (I named it the old lady afro), is starting to calm down.

I would say that my taste buds are finally back, and I was able to eat the things that repulsed me by mid November after September chemo was done.

Blessings on your recovery!

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