← Return to My TC journey: Taxotere (docetaxel) & Cytoxan (cyclophosphamide)

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I have had 3 full infusions of the TC regimen. I started experiencing a bad skin reaction on my hands/feet after the 1st infusion. My oncologist did not want to lower the strength and just prescribed more steroids every day. Each infusion the condition of my skin gets worse. My hands are red/stiff feeling and the skin is peeling. The same goes for my feet but to a lesser degree. It has been 2.5 weeks since the third infusion and it is not better. I am not willing to do the fourth infusion with the Taxotere due to these side effects. I am going to finish the 2nd drug of the 4th infusion.

Has anyone had this problem with their hands/feet? I have read that this continue to happen even weeks after stopping chemo. How long will it take for these symptoms to go away. I am using a thick moisture cream to prevent the skin cracking.

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Replies to "I have had 3 full infusions of the TC regimen. I started experiencing a bad skin..."

Some of you may have read my other posts about my skin reaction to the Taxotere. My 4th and final infusion is scheduled for later this morning. I have had such a bad reaction to the Taxotere which gets worse with every infusion that I am not sure I am going to finish it. My hands stay red and with skin peeling despite being on steroids before and after the last infusion. I ended up on a Medrol dose pack and it still did not help. Only now 3 weeks later has the redness and stiffness decreased a little. I can't take hot showers can only tolerate lukewarm water on my hands or it stings/burns.

My thoughts are that I am willing to take the Taxotere but at a reduced strength hoping for less of a reaction. I do not want permanent skin damage from this drug. I have gotten 3 full strength rounds. My tumor was small 1.2 cm with clear margins and lymph nodes, but tumor grade was a 3. CK-67 score was around 30-31 as far as I can remember and I had a bilateral mastectomy. I am also scared not to do the full strength will it matter that much?

Opinions anyone or advice?