Some of you may have read my other posts about my skin reaction to the Taxotere. My 4th and final infusion is scheduled for later this morning. I have had such a bad reaction to the Taxotere which gets worse with every infusion that I am not sure I am going to finish it. My hands stay red and with skin peeling despite being on steroids before and after the last infusion. I ended up on a Medrol dose pack and it still did not help. Only now 3 weeks later has the redness and stiffness decreased a little. I can't take hot showers can only tolerate lukewarm water on my hands or it stings/burns.

My thoughts are that I am willing to take the Taxotere but at a reduced strength hoping for less of a reaction. I do not want permanent skin damage from this drug. I have gotten 3 full strength rounds. My tumor was small 1.2 cm with clear margins and lymph nodes, but tumor grade was a 3. CK-67 score was around 30-31 as far as I can remember and I had a bilateral mastectomy. I am also scared not to do the full strength will it matter that much?

Opinions anyone or advice?