Muscle Weakness and Eliquis - How to diagnose/test for cause?

Posted by devotion @devotion, Jan 13 4:22pm

I've always had somewhat loose ligaments but it is getting much worse since taking Eliquis, which I started about 1.5 years ago. I am now 75 years old. I take a low dose but my body is very sensitive to all medications. I am hesitant to get a Watchman, and am wondering if there is some diagnostic procedure to determine if Eliquis is causing the problems of muscle weakness?

I appreciate that many people have posted about this concern of muscle weakness in relation to taking Eliquis - WHAT DO THE DOCTORS SAY???? Mine tend to know very little about this.

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Profile picture for Zebra @californiazebra

Sorry to hear of your reaction but so glad I read this. I have been taking Eliquis for 4 months and it’s causing real fatigue but I’ve also had sudden joint pain all over for 2 months especially in the morning. Hands and feet are so painful. It improves with movement. Elbows, knees, ankles to a lesser extent. I was wondering if it was related to taking Eliquis because nothing else has changed in my life. Funny, they still have trouble getting blood out of me at the lab. No change in bleeding if I get a cut. Hope it all clears up for you.

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@californiazebra

Six months after off Elquis, I'm still working my way to "better". I still have wooden foot syndrome (as one person put it) It goes away after a bit of walking. As long as I'm moving, joints don't hurt, but sitting as long as dinner means moving a bit to get my hip muscles working and ease the pain. If there are this many people in different titles of Eliquis usage on Mayo, how many are not. My guess is that nobody simply makes up the side effects and reading how others have coped helps. Eliquis is great for removing blood clots and most likely most people do not have a problem. My guess is that it for me it would have been better on a smaller dose, Trust yourself. All of us with the same frustrating problems send you caring thoughts!

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Profile picture for gloaming @gloaming

@wagonroad I don't see a claim to an initial purpose to 'weaken the prostate muscle' for apixaban, which is what Eliquis is. Would you happen to have a source handy?
https://www.drugs.com/mtm/apixaban.html
https://snuggymom.com/does-eliquis-affect-urination/

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@gloaming You are correct sir. I was thinking of flowmax.

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Profile picture for wagonroad @wagonroad

@gloaming You are correct sir. I was thinking of flowmax.

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@wagonroad Whew! I was wondering if I'd missed something as a patient who has been on apixaban for about eight years now. 😀 My late dad was a user of flomax.

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Profile picture for timely @timely

@devotion

My first cardiologist, who was Indian, said that I could take Curcumin when I asked her.
She knew that I was taking Eliquis.
Curcumin has so many positive benefits.

I only have avoided ginger.

I seem to be fine.

We use garlic in cooking. I did not connect the garlic and blood thinning.

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@timely Which cur cumin product do you take? and dosage? Tx

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This is helpful, because the cardiologist is NOT. They give me the puzzled response to my queries about Eliquis and joint pain, muscle pain. Clearly, these things got worse almost immediately after starting Eliquis. But the cardiologist dismissed it as a cause, more than once. So I go online, not just here but doing a simple Google inquiry and, lo and behold, YES, Eliquis either by itself or in combination with statins, can cause serious issues. My medial collateral ligament in my right knee tore, my knees and hands are a mess, and I have aching muscles all over. I don't feel like waiting for another medication, and even though I do have several risk factors with my heart, including AFib, I would rather go back to the baby aspirin once daily and take the risk rather than limping around with bad knees ready to pop and hands that I need to play guitar and make a living. I'm quite disgusted at the lack of knowledge of these matters by supposed "experts" in the field. Thanks for this post and the associated comments that reinforce my own experiences.

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Profile picture for gabriig @gabriig

@californiazebra

Six months after off Elquis, I'm still working my way to "better". I still have wooden foot syndrome (as one person put it) It goes away after a bit of walking. As long as I'm moving, joints don't hurt, but sitting as long as dinner means moving a bit to get my hip muscles working and ease the pain. If there are this many people in different titles of Eliquis usage on Mayo, how many are not. My guess is that nobody simply makes up the side effects and reading how others have coped helps. Eliquis is great for removing blood clots and most likely most people do not have a problem. My guess is that it for me it would have been better on a smaller dose, Trust yourself. All of us with the same frustrating problems send you caring thoughts!

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@gabriig

I'm unutterably frustrated and disgusted with supposed "specialists" who are unaware of these concerns about Eliquis (and a lot more) when a simple online query reveals the issues with joint pain and weakness, muscle aches and weakness, worsened arthritis symptoms and other issues that they seem ignorant of. So thanks for the comments. I'm in touch with my regular GP provider, as well as the 'cardiologist' and regardless of the potential risks, am discontinuing the Eliquis immediately. I'd rather take the risk of dying but feeling better in the meantime than taking drugs that make me feel terrible with unclear and unproven benefits to my heart. Not being stupid, but I'm not happy at all. I depend on my hands to make a living, and they are a mess now after about two weeks of this supposed miracle drug Eliquis.

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