Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Posted by dougs72 @dougs72, Jun 22, 2024

Has anyone ever been on Duloxetine (Cymbalta) for nerve pain? I've had 2 doctors push this on me. I know that the side effects can be terrible and getting off of it difficult as it requires titration. One time I remember taking one pill, and not liking the way it made me feel, so not taking any more, and still feeling the "weirdness" from it 2-3 days later. and that was only 30 mg Please pass along any experience or advice from this medication?

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I was given Duloxetine by a physio for severe sciatica and took it for around 8 weeks. No side effects at all and didn't do me any good either so I stopped taking it. Just nothing. Never had any kind of effects when I stopped either. She said it was supposed to be one of the most successful types of meds for long term pain.

Similar with Gabapentin, again nothing. Then Amitriptyline which caused headaches. Then tried me on Pregabalin and that was awful, I was dropping things and my legs were like rubber soon as I started it. Horrible.

These type of meds didn't work for me but we are all differen, one of them could help you. I'd at least try them and see how you get on.

I ended up having to take Tramadol and then Morphine which are great painkillers at first but your body gets used to them and they become far less effective over time. I wouldn't consider them a long term solution. Even if you up the dose to compensate you'll end up itching like hell as well as appetite loss and constipation. Use them very sparingly if you have to go down that road.

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Profile picture for coloradomama1 @coloradomama1

I take 120mg of Cymbalta for Chronic Migraine Disease and Fibromyalgia. I have gone off of it before and my pain increased significantly. I also use THC/CBD salve and gummies. The gummies are micro dosed so I can adjust as I need to. The introduction of medical cannabis has been the only thing that allows me to function during the day. It doesn't take my pain away but it eases my nerves and relaxes me.

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@coloradomama1 I having putting thc salve on my feet for a while . It has helped so much . Looking at trying cymbalta . Wish you the best .

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Profile picture for sheceegold @sheceegold

@dougs72 Agreed. CBD doesn’t help with everything but it is better than most drugs. For nerve compression in back pain I suggest you explore what helped me. An MRI showed nerve compression in spinal discs. Minor surgery (a disc decompression) gave almost immediate relief. Over night in the hospital and I was up the next day. No physical therapy or follow-up was needed. 15 years later and still pain free. CBD balm relieves pain in my knee and toe that was injured about 10 years ago. It, too, give almost immediate relief but needs repeat appliation about 10 hours later . CBD is my first go-to attempt at relief. And it usually works.

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@sheceegold I tried cbd salves on my feet . I get a thc salve fromMaryjanesmedicials.com . I apply it on my feet several times a day. I do not make anything from the company above .

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How do you manage your tolerance to thc? I find it works at micro dose but then I need to increase it or it stops being effective. Stopping causes my pain to spike so I finally stopped using it because the dose got so high it was making me anxious

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Profile picture for kbirchem @kbirchem

@sheceegold I tried cbd salves on my feet . I get a thc salve fromMaryjanesmedicials.com . I apply it on my feet several times a day. I do not make anything from the company above .

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@kbirchem I get my CBD balm from Charlottes Web and most times I apply it 1 X/day. Sometimes in AM and at bedtime. It has 450 MG CB per 1.5 oz (43gm). I, too, have no connection to the company. I hope you’re doing well.. Sheila

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I take Duloxetine for my fibromyalgia. The problem is, it's not going to be available much longer.

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Profile picture for ohiogirl48 @ohiogirl48

I take Duloxetine for my fibromyalgia. The problem is, it's not going to be available much longer.

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@ohiogirl48
Why do you say it’s not going to be available?

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Profile picture for beachlife67 @beachlife67

@ohiogirl48
Why do you say it’s not going to be available?

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@beachlife67 Express Scripts told me a few months ago it would be unavailable until further notice, but from reading all these posts, that isn't the case with everyone. I spoke with a pharmacist at Express Scripts today, and they told me that they haven't had it in stock since February. That seems silly since I've been receiving it since then, and I currently have half of a 90-day supply and a full 90-day supply left. Apparently, the supplier Express Scipts uses can no longer get it from the manufacturer. The pharmacist couldn't tell me why. They also told me I could get 90-day supplies from a retail pharmacy, so the retail pharmacy's supplier isn't having any trouble getting it. So, it looks like this is an Express Scripts issue only. Sorry for the confusion.

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Tks for posting this I was put on it two years ago and I stopped it because of weight gain and it never helped my depression

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I tried Cymbalta for my chronic pain and it didn’t help me at all. I also had very uncomfortable side effects. I am so sensitive to so many medications though, and everyone is different, so maybe it could help you. I think I forced myself to stay on it for about two weeks, still no go.

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