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C Diff issues after completing antibioitcs

Posted by vdyjor @vdyjor, Sep 1, 2025

I was diagnosed with c diff 9 weeks ago. I went through 2 different antibioitics. It seemed better but now almost 4 weeks later I am still having bowel movements 8 t0 15 times a day. Nothing seems to help slow or stop it. The only time I get a break is when I go to bed at night. I may get up once all night but then it starts up as soon as I get up in the morning. Does anyone have any ideas or suggestions as to what this maybe causing this? The infectious disease doctor gave me Cholestyramine to take once a day but it has not helped.

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GetWellSoon26 | @vijay26 | May 4 11:21pm

Sorry that you had such a long battle w C.difficile pathogen.

Hope you are free from it by now 100%.
Good luck
VJ

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cas924 | @cas924 | May 5 7:23am
In reply to @grammato3 "@vijay26: I'm glad to hear you're doing well! I can understand your concerns about picking up..." + (show)
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@vijay26: I'm glad to hear you're doing well! I can understand your concerns about picking up C Diff but it's a very virulent bacteria. It's extremely difficult to eradicate because its spores are resistant to common alcohol-based hand sanitizers and many cleaning agents.

I had been less fortunate as I did not respond to either Vanco nor fidaxomicin. I was ultimately hospitalized where it was determined I had CMV colitis requiring a lengthy course of antifungals via PICC line and subsequently determined I also had ICI (Immune Checkpoint Inhibitor Colitis) as a result of the immunotherapy I'd been on for my metastatic melanoma. It was a LONG fall and winter but I'm thankfully emerging into spring feeling stronger and better with the help of Entyvio infusions getting my gut back into the healthy state it had been!

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@grammato3 Oh my goodness you have been through A LOT. I’m so happy for you that you are finally getting that guy back into a healthy state!

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Susan, Volunteer Mentor | @grammato3 | May 5 10:47am
In reply to @vijay26 "@vdyjor I had an Indian dr. Santa Kumar who runs the dept of Infectious disrases. He..." + (show)
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@vdyjor
I had an Indian dr. Santa Kumar who runs the dept of Infectious disrases. He told me not to have any relatives, spouse visiting me as a first thing to prevent spread of my infection to my 81 yr old husband. He did not listen to any drs. He wore their hospital gowns, mass and gloves to get in my private suit to visit w me. He brought me a big piece of Pizza that I love to eat anyway.

Grammato3: how old are your grand kids? Keep them away.from you for a while, till you are 100% infection free. They tested my poops again and again to make sure there are no gets in it.

Diarrhea-cpnstipatipn-diarrhea"-constipation..normal w Vancomycin medicine.

Is the poop well formed or not?
Check it out daily.
Good luck.
VJ

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@vijay26 I had been kept on isolation and am over my infection, thanks!

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momac59 | @momac59 | May 6 9:42am

Last September I got C-diff & ecoli. Loads of fun! I w as treated with powerful anti biotic & it took awhile but by Christmas I was feeling better despite some IBS symptoms. Gastroenterologist said it was “post infectious IBS” & would take a while to recover. March I got a recurrence even though I was so careful with bleaching, hand washing, etc but this one set off a HUGE autoimmune firestorm (I have Lupus & GCA) & I end up in the hospital. After 8 weeks I am actually feeling better having been treated not only with antibiotics again but after treatment for my autoimmune involvement. My gut is still very sensitive but I’m down to one BM a day even though it’s not solid, I’ll take the improvement.
Over the last months I’ve done a lot of reading about the gut & have looked into SIBO, which is Small Intestinal Bacterial Overgrowth that a lot of Cdiff patients end up with. Check it out. I also got approval from my Dr. to go on probiotics; Florastor or Culterelle are good to switch back & forth to try & build back good bacteria. And finally, cleaning up my diet has helped immensely to get reduce all that inflammation that causes so many symptoms.
I really hope this all helps & that you are on your way to better health soon!

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vdyjor | @vdyjor | May 6 11:01am

I am so sorry This is such an awful infection. It really controls your life when dealing with it.
Thank you for sharing your experience and information.
Feel better soon. 🤗

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