Camzyos / mood swings or over-reacting?appreciate anyone's exp

Posted by jmr091805 @jmr091805, Jun 3, 2025

Has anyone experienced mood swings or higher highs and lower lows emotionally after starting Camzyos or after dosage has been raised? I have felt so low usually in the mornings and so much more energized when feeling up. Not limited to that either. I'm over-reacting to things. All of this is out of character for me.

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brumasterj | @brumasterj | Jun 4, 2025

I did have ups and downs but im not so sure its camzyos?
I think it was just because so much had happened with my heart in such a short period if time! Then being told i had multiple exercise induced heart failures was hard to sink in!
For many years i went misdiagnosed by my Primary and local cardiologist when i would describe i felt like i had a hole in my heart and wasnt moving any blood while exercising they would blow it off as allergies, exercise induced asthma, or my age and different things!
I think anytime the heart has trouble it can lead to emotional highs and lows:)
But make sure you talk to your cardiologist and primary care about your symptoms

deniseh72 | @deniseh72 | Mar 30 10:14am

I'm just starting and currently on 2.5mg day 23, and I'm noticing I have been feeling really low and hard to snap out of it. I get this strong urge to cry starting about an hour after taking it. Also have felt really overwhelmed. This is not my usual self at all.

420gramps | @420gramps | 4 days ago

I started Camzyos 6 days ago. After 3 days, I started overreacting to situations, and becoming very emotional. I suffer with CPTSD, and this all became very confusing. Major overstimulation, and wanting to “hide” from the world. Inability to focus and sleep also has occurred. I spoke with my cardiologist this morning and hoping to hear back today on direction.

christine270 | @christine270 | 2 days ago

In reply to @420gramps "I started Camzyos 6 days ago. After 3 days, I started overreacting to situations, and becoming..." + (show)

@420gramps Hello there…started Camzyos in Oct 25…
I experience all of the above as well as feeling overwhelmed. I’m hanging in there with prayer and taking one hour at a time!
Hoping for good direction from your cardio doc. All the best!

420gramps | @420gramps | 2 days ago

In reply to @christine270 "@420gramps Hello there…started Camzyos in Oct 25… I experience all of the above as well as..." + (show)

@christine270
Yours has hung on that long?! I did talk to her yesterday, she contacted Camzyos, they said that’s not a side effect. I referred her to the forum, and a simple Google search. I’ve started feeling better by sequestering myself, and texting with a long time friend about light stuff. Still not sleeping well, and no appetite.
I hope the best for you, I’m here.

christine270 | @christine270 | 2 days ago

In reply to @420gramps "@christine270 Yours has hung on that long?! I did talk to her yesterday, she contacted Camzyos,..." + (show)

@420gramps Hello there…
I am thinking that they are most concerned about the liability aspects related to the side effects…palpitations, swelling, heart failure, etc…the other changes such as poor sleep, withdrawal, sadness…while quite difficult for many of us are perhaps not as life threatening from the drug company and doc’s point of view.

Glad you have a great text buddy and feel better as you make your path in your own way. I tried reflexology for poor sleep…putting pressure on the inside of your wrist with your thumb…seems to make me very sleepy quickly. I don’t have an appetite either…lost ten pounds recently. Day by day…take care…we can do this! 🙏 Thank you, I’m here too!