Has anyone experienced depression after taking praluent?

Whew, so glad it went away @kallettla .
Good thinking to ask your pharmacist. Have you been able to have a conversation with your doctor about your reaction? Maybe they’ve heard of this before, or can help you figure out which thing caused your problems. I agree, anything to help other people not having the problem is a good thing.

For a time, I took 5mg rosuvastatin (generic Crestor) two times a week. My understanding is it is a statin that stays in our bodies 3-4 days so that type of schedule makes sure there’s always some. Fingers crossed your trial run of Crestor goes well!

This scare of anaphylaxis with tingly lips and tongue was your 2nd injection? Did anything happen on your first?

Pins and needles to hear more. 😀

Dear friend, forgive me I just scanning these posts and not reading them word for word. So I may be way off track. But let me tell you what happened to me one year ago. First, the answer is custom compounding medicine without the added preservatives. Okay, so here's what happened. Having had perfect health my 65 years, I ended up in the ER twice with BP climbing over 200+. Then 5 drugs later, it kept escalating and I went into depression. My doctors and family told me to see a shrink, but my research said something different. I've had raging chemical allergies for 2 years now, and they told me to watch out for preservatives in medicines. I never knew how they would make me feel, but I promise you this, with custom compounding of my hypertensive medicine, I am a perfectly normal, functioning, well-adjusted person. I'll stop here because this is a lot to take in. All the best to you. And feel free to ask any questions you wish. All the best, Julie

Checking in, @dlkreps
I want to check in with you to see how you are you doing since last commenting you were headed to a lipid specialist for cholesterol management. You have been working through quite a bit with getting a stent and medication side effects.

I thought of you because we had discussed my experience at Mayo Clinic Statin Intolerance Clinic. I thought you may like to meet @wgr123 who just posted about a recent visit after problems with Repatha. I am not sure if I had told you my experiences were consistent with both Repatha and Praluent.
https://connect.mayoclinic.org/comment/1521558/
My quality of life is improving having addressed my symptoms these past months. It has taken consistent, regular focus and effort on the entire scope of mind, body, spirit to be where I am.

How are you doing? Has any particular thing specifically helped, or caused problems?

I am not sure what kind of stent you had put in, but I had AAA three years ago and have aortic stent. I developed depression a few weeks after surgery and it lasted till six weeks and my surgeon said it's a normal effect of any kind of heart surgery so I would also check with your cardiologist.

I am 61 and have genetically high cholesterol. After developing more plaque and a triple AAA, which was repaired three years ago, I am trying to get my cholesterol down naturally, but it is not working well. My LDL is 190 and my doctor has gotten an approval for the PRAULENT I had a terrible reaction to statins after just 10 days was achy. Everywhere felt my muscles were injured and was kind of bedridden. I am just looking to see what kind of reactions people have had when starting the shot and how much they are seeing at lower their cholesterol by. I eat very little in fact, not enough at 1800 cal. I work out five days a week and it is doing nothing to the cholesterol numbers.Thank you.