1. < Heart & Blood Health

Has anyone experienced depression after taking praluent?

Posted by Dkrepid @dlkreps, Mar 27 7:41pm

Has anyone experienced depression after taking praluent? I recently started this PCSK9 after being on rosuvastatin for 3 weeks and experiencing such crippling fatigue and muscle soreness. I’m a very active 62 year old male and am trying to manage my new life after having had a stent placed in LAD.

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Mentor
Janell, Volunteer Mentor | @jlharsh | 1 day ago
In reply to @kallettla "Yes, thank you for asking. It went away in 2 to three hours. I did not..." + (show)
@kallettla

Yes, thank you for asking. It went away in 2 to three hours. I did not feel well all day, but tonight, I am feeling much better!

I called the pharmacist and he couldn't tell me what would be the most likely allergen...polysorbate, histadine, or the actual medication.

He also told me there is a statin out now that recently became generic. It is very powerful and has fewer side effects: pitavastin. I will first try the generic Crestor once a week and see what happens. He said people don't always take it daily.

Maybe this will help people. I will put it in a post tomorrow.

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Whew, so glad it went away @kallettla .
Good thinking to ask your pharmacist. Have you been able to have a conversation with your doctor about your reaction? Maybe they’ve heard of this before, or can help you figure out which thing caused your problems. I agree, anything to help other people not having the problem is a good thing.

For a time, I took 5mg rosuvastatin (generic Crestor) two times a week. My understanding is it is a statin that stays in our bodies 3-4 days so that type of schedule makes sure there’s always some. Fingers crossed your trial run of Crestor goes well!

This scare of anaphylaxis with tingly lips and tongue was your 2nd injection? Did anything happen on your first?

Pins and needles to hear more. 😀

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