Prolia treatment for osteoporosis: What is your experience?

I have received one injection of Prolia and I am struggling with constipation to the point where I am not willing to continue with the Prolia. My doctor dismisses constipation and back pain as non side effects of Prolia. I have had long standing constipation uses d/t taking an antidepressant, hypothyroidism, statin drugs. I have seen a gastroenterologist with suggestions for fiber. Fiber makes it worse. I am taking miralax. Has anyone else suffered from this?

I will be having my fourth shot this next week, so far I do not have any side effects. Prolia does have a copay card available to help with cost of shots.

I am tentative about this drug also. I have hashimoto's disease, gastroparesis, kidney disease that is not active, and osteoporosis. My last DEXA scan was -4.5 at the hip and -2.5 at the spine. After a year and a half of resistance training twice a week for an hour each with a Wellness Coach and by a physical therapist, my spine is now not losing any bone but my hip has lost 5% in 2 years. I have been taking 2000 Vit D3, adequate calcium since I have calcification in my arteries (I am 68 years old), along with Vit K2, and magnesium and a multiple vitamin. My hesitation is that 3 totally different drugs have sent me to cardiac care for 5 days or more with blood pressure over 200. Acthar, Livalo (a cholesterol med) and Tacrolimus. At all times I had just visited my nephrologist & my kidneys were fine in that I was not dumping protein. I have always had excellent creatinine clearance... just protein loss. I am not able to take any of the Fosamax or pills such as that. They make me dump more protein. Unless someone can steer me to someone that can do some genetic counseling to see why my body is not metabolizing drugs like everyone else's, I am not inclined to take Prolia. I don't know where to turn for more help. My endocrinologist just keeps pushing Prolia. But at least I have built muscle to support these old bones until they just break. Any advice would be helpful.

I will be having my fourth shot this next week, so far I do not have any side effects. Prolia does have a copay card available to help with cost of shots.

I am tentative about this drug also. I have hashimoto's disease, gastroparesis, kidney disease that is not active, and osteoporosis. My last DEXA scan was -4.5 at the hip and -2.5 at the spine. After a year and a half of resistance training twice a week for an hour each with a Wellness Coach and by a physical therapist, my spine is now not losing any bone but my hip has lost 5% in 2 years. I have been taking 2000 Vit D3, adequate calcium since I have calcification in my arteries (I am 68 years old), along with Vit K2, and magnesium and a multiple vitamin. My hesitation is that 3 totally different drugs have sent me to cardiac care for 5 days or more with blood pressure over 200. Acthar, Livalo (a cholesterol med) and Tacrolimus. At all times I had just visited my nephrologist & my kidneys were fine in that I was not dumping protein. I have always had excellent creatinine clearance... just protein loss. I am not able to take any of the Fosamax or pills such as that. They make me dump more protein. Unless someone can steer me to someone that can do some genetic counseling to see why my body is not metabolizing drugs like everyone else's, I am not inclined to take Prolia. I don't know where to turn for more help. My endocrinologist just keeps pushing Prolia. But at least I have built muscle to support these old bones until they just break. Any advice would be helpful.

I am tentative about this drug also. I have hashimoto's disease, gastroparesis, kidney disease that is not active, and osteoporosis. My last DEXA scan was -4.5 at the hip and -2.5 at the spine. After a year and a half of resistance training twice a week for an hour each with a Wellness Coach and by a physical therapist, my spine is now not losing any bone but my hip has lost 5% in 2 years. I have been taking 2000 Vit D3, adequate calcium since I have calcification in my arteries (I am 68 years old), along with Vit K2, and magnesium and a multiple vitamin. My hesitation is that 3 totally different drugs have sent me to cardiac care for 5 days or more with blood pressure over 200. Acthar, Livalo (a cholesterol med) and Tacrolimus. At all times I had just visited my nephrologist & my kidneys were fine in that I was not dumping protein. I have always had excellent creatinine clearance... just protein loss. I am not able to take any of the Fosamax or pills such as that. They make me dump more protein. Unless someone can steer me to someone that can do some genetic counseling to see why my body is not metabolizing drugs like everyone else's, I am not inclined to take Prolia. I don't know where to turn for more help. My endocrinologist just keeps pushing Prolia. But at least I have built muscle to support these old bones until they just break. Any advice would be helpful.