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Brinsupri (aka Brensocatib)
FDA approved Brensocatib today. Hooray for us. Let’s hope we have access to it as soon as possible and it gives us some measure of relief. Thank you to all the scientists and doctors and patients!
https://www.multivu.com/insmed/9347351-en-fda-approves-brinsupri-brensocatib
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I will message my pulmonologist about his sources for BMI being a factor in prescribing brensocatib/ brinsupri for me. Thank you for all of the input and comments. I keep learning new information each time I check in-
actually, I’m going to ask my md about it next week. the pharmacist with brinsupri mentioned it, but she was very in depth and maybe misspoke about a small area in the trials. I’ll try to review.
irenea8... I had my lung function test yesterday and there was dramatic improvement since January. I've been taking Brinsupri for 5 weeks and noticed a decrease in mucus and lightening in color. My pulmonologist was thrilled and shared that another patient (an older patient with 30 year history of BE) had similar results. The doctor discontinued Azithromycin, since it seems Brinsupri does the anti-inflammatory work. I still have ciprofloxacin and tobramycin on hand, ready for the next exacerbation, which we expect in the fall and winter seasons. I was having exacerbations every 11 days since January.
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10 ReactionsHas anyone had side effects from brunsupi? Ive never been able to take the big 3 because of other autoimmune. Plus I always get the worst side effects from drugs. Please let me know.
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1 Reaction@egayle187 , So good to hear that Brinsupri is working for you. How long did you take azithromycin before you stopped? I am also on it, but after I started Brinsupri I am wondering if I should stop it too.
Hope you continue to do well.
Ling
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1 ReactionI’ve been on Brinsupri for a month. About a week ago I started having what my Pulmonologist has said is an exacerbation. Now I had bloodwork, sputum, & chest x-ray done within the week and they’ve all but ruled out any infection. I don’t think it has anything to do with the Brinsupri, but I’ve had exacerbations before but this time I had the usual symptoms plus other ones I’ve never had during an exacerbation. Fever (1 day only) vomiting, & body aches. The xtra symptoms were only 1 day also. I was put on Levaquin and Prednisone taper 9/28, still having hard time coughing up mucus though. I attribute some of that to my other lung disease Pulmonary Fibrosis, which doesn’t allow me to fully expand my lungs to get a lot of air behind the mucus to help cough out. In the past 2 years I looked back in my records and seem to have exacerbations every spring & fall, which leads me to believe it is environmental triggers. Although I must add I always wonder what and why. Make sense? I’m very glad some and seems like most are having good success so far, and hopefully more of us will too. In the meantime I will stay the course and do what the Dr.s tell me. And I’ll be curious to see how it goes after my exacerbation passes.🤞. God bless us all.
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3 Reactions@egayle187 So glad to hear this news for you. Overall that is such good news and one I am glad to hear for many reasons.
Do I understand correctly, the exacerbations for you have lessened?
So hoping this is going to be an outcome for most on Brinsupri.
Remarkable and wonderful for you "dramatic improvement."
Barbara
@egayle187 Irene -
Did you with your insurance plan and pulmonologist have any trouble getting approval for the Brinsupri for you?
Was it prescribed by a local pulmonologist at a Center of Excellence?
Barbara
Plans and approval for Brinsupri.
How is it working for those in these different circumstances and health plans with the D plan for the Brinsupri.
Just wondering if local pulmonologists prescriptions are having difficulty for their patients getting approval compared to such facilities as NYU Langone or NJH etc.
How it is working for those agreeing to starting Brinsupri.....in getting approval for Brinsupri under the following circumstances/plan arrangements.
Advantage Plans with D Plan built in
vs.
Medicare with Supplemental Plans that include, within them, D Plan built in.
vs
Medicare, Supplemental Plan and Separate D Plan.
Barbara
@crepass
I don't know if you spoke to your pharmacist yet, but I think your thought about her misspeaking on a small area in the trials is correct. I have not read this nor did I hear anyone mention it in the two videos (one of which was Dr. Daley) I listened to.