know any causes of Chronic Nausea?

Posted by socalfriend @socalfriend, Sep 26, 2023

I'm really really seeking any type of insight into unusual or rare causes of chronic nausea. I am a 27yo female and have had chronic moderate-severe nausea daily for going on 10 months with no known cause. I have ruled out pregnancy and GERD, and know that it is not from anxiety (I am a MH professional). It is seriously debilitating and I have seen many specialists that all have coincidentally found something but not the cause of the nausea. The other symptoms I have include headaches, palpitations/PVC's, chronic fatigue, occasional nightsweats, dizziness/chest discomfort when standing up, and just an overall sense of unwellness. In the midst of this search for answers I was diagnosed with Hashimoto's, but dont believe it's the cause for many of these symptoms as the lump in my throat feeling and fatigue have improved a little w/ Hashimotos treatment but most of the symptoms I mentioned previously have only continued to get worse. Does anyone know of any possible causes for the symptoms I have been struggling with, particularly the nausea? Or is anyone familiar with Hashimotos and has had a similar experience of having this intense persistent nausea for months?? I feel like my medial providers aren't thinking outside the box and aren't taking it as seriously as I am to consider potential causes. I feel very desperate as I can feel myself getting sicker. This will sound dramatic but since I have only continued to get sicker over the past 10 months its hard not to wonder if I have some type of serious illness thats just going untreated. Thanks in advance.

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I was diagnosed with gastroparesis many years ago and it's caused by the autoimmune disease. It's affecting the nerves to my gut. And it definitely causes nausea!

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I have frequent nausea and it's most likely related to my silent migraine diagnosis. Bonine (OTC) helps a lot. I also have a "reliefband classic." I use if with reliefband conductivity gel. It is placed on the wrist. You can google it. It's rather expensive. Around $149.00.

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Profile picture for charles826 @charles826

My husband has been nauseous for over a year. He has had all test and they come back ok. He is 81 and I don’t know what to do next. Drs seem to have no answers. He can’t go on like this

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Also a few good old fashioned soda seem to work for a while.

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Gastroparesis is sometimes linked to persistent nausea. Have you seen a GI doctor? An emptying test can be ordered to see whether your stomach is emptying too slowly, causing the nausea (it's not a long or terrible test to take: on one day you drink a radioactive drink and on the second day you eat a plate of radioactive scrambled egg and toast with jam and they essentially capture it over a period of time - I think it's about 20-30 mins or so - and then figure out whether your stomach is emptying too fast, too slowly, or normally). On mine, they sandwiched the egg between the toast WITH the jam which didn't make me too happy, lol.
https://www.mayoclinic.org/diseases-conditions/gastroparesis/symptoms-causes/syc-20355787
Also, my oldest noticed almost immediately that his "jippy tummy" seemed to clear right up after his Vagus Nerve Stimulator was implanted (for his epilepsy). Prior to that, he'd been hospitalized for weeks due to Cyclical Vomiting - which apparently is also linked to the Vagus Nerve. I hadn't before then realized that the Vagus Nerve is connected to the gut. Perhaps just another avenue to explore. Hope you find answers and relief quickly.
Best, Pauline.
https://vagusnerve.com/the-impact-of-the-vagus-nerve-on-nausea-a-comprehensive-analysis/

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I'm so sorry you're having to deal with all of this!! (I type sucking on a Zofran) Have you had your Vargus nerve checked ? (not sure I spelled that right) I am 71 and have been dealing with this for about 4 years..they finally diagnosed my stomach a "J" shaped..I 've had alot of digestive issues..and may have Scleroderma..he won't' tell me (for 2 years he proclaimed it was a miracle I didn't have it.. this year he has an assistant who says "we can't rule it out"..I'm going with miracle!!) The nausea is completely debilitating..I spend alot of time in bed. nauseated.. I do take promethazine every 6 hours along with the zofran and eat 6"small" meals through out the day.. one thing I tried I would Not suggest is the scopolamine patch.. extremely constipating!!! I feel for you!! Praying for you to get some answers!!

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Profile picture for michgirv @michgirv

I was diagnosed with gastroparesis many years ago and it's caused by the autoimmune disease. It's affecting the nerves to my gut. And it definitely causes nausea!

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I was in the hospital in April for suspected gastroparesis, but by day 5, I was “borderline” on the liquid test and on day six for the delicious, scrambled radioactive egg I was normal. I also have an autoimmune disease which they didn’t think was connected. Mine is a connective tissue disease (NrAxSpa). It felt like I ate bricks and couldn’t digest them. Still trying to understand why. I now eat 6 small meals and carry Zofran. Have you had it long?

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Profile picture for migraineelaine @migraineelaine

Also a few good old fashioned soda seem to work for a while.

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yikes--I meant soda crackers!

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Profile picture for pm56 @pm56

I was in the hospital in April for suspected gastroparesis, but by day 5, I was “borderline” on the liquid test and on day six for the delicious, scrambled radioactive egg I was normal. I also have an autoimmune disease which they didn’t think was connected. Mine is a connective tissue disease (NrAxSpa). It felt like I ate bricks and couldn’t digest them. Still trying to understand why. I now eat 6 small meals and carry Zofran. Have you had it long?

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I was diagnosed in 1997 and eventually went to the University of Florida Shands where they did manometry testing to see where the tract was malfunctioning. It wasn’t just slow but peristalsis wasn’t in sync causing many problems. They were talking about a gastric stimulator when I developed some numb areas down nerve roots (down leg to foot, certain areas of fingers and hands). Fast forward to diagnosis of mono neuritis multiplex, then systemic vasculitis. I have a history of rheumatoid arthritis as a child. These were autoimmune problems and I began high dose prednisone and cytoxan. At that time gastroparesis wasn’t connected with autoimmune problems. Well, the first thing to improve was my stomach. The doctors at Shands were going to use my case in grand rounds. Today you find it listed in symptoms of many autoimmune diseases. The cytoxan didn’t work and I began IVIG infusions monthly. That was in 1998 and I continue them today. I was able to wean from the prednisone after four years and now pulse it around the treatment. I still have some trouble with gastroparesis but NOTHING like before. I too eat small meals, and Zofran is my constant companion. Now another part of my autonomic nervous system is failing and I’m having a terrible time maintaining my BP high enough to stay upright. There are so many other things in my history that I could write a book. My body loves attacking my tissues. I have Sjögren syndrome, Graves’ disease, progressing sensory and motor neuropathy. All around mess but I’m still here and have seen far more than I ever thought I would. So all I can say is keep advocating for yourself and don’t give up until you get some answers.

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Profile picture for michgirv @michgirv

I was diagnosed in 1997 and eventually went to the University of Florida Shands where they did manometry testing to see where the tract was malfunctioning. It wasn’t just slow but peristalsis wasn’t in sync causing many problems. They were talking about a gastric stimulator when I developed some numb areas down nerve roots (down leg to foot, certain areas of fingers and hands). Fast forward to diagnosis of mono neuritis multiplex, then systemic vasculitis. I have a history of rheumatoid arthritis as a child. These were autoimmune problems and I began high dose prednisone and cytoxan. At that time gastroparesis wasn’t connected with autoimmune problems. Well, the first thing to improve was my stomach. The doctors at Shands were going to use my case in grand rounds. Today you find it listed in symptoms of many autoimmune diseases. The cytoxan didn’t work and I began IVIG infusions monthly. That was in 1998 and I continue them today. I was able to wean from the prednisone after four years and now pulse it around the treatment. I still have some trouble with gastroparesis but NOTHING like before. I too eat small meals, and Zofran is my constant companion. Now another part of my autonomic nervous system is failing and I’m having a terrible time maintaining my BP high enough to stay upright. There are so many other things in my history that I could write a book. My body loves attacking my tissues. I have Sjögren syndrome, Graves’ disease, progressing sensory and motor neuropathy. All around mess but I’m still here and have seen far more than I ever thought I would. So all I can say is keep advocating for yourself and don’t give up until you get some answers.

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Thank you for sharing. Interestingly enough also have developed “axonal neuropathy” - I don’t have diabetes and the neurologist doesn’t believe the underlying cause to be neurological - he believes it to be inflammatory, so I’m still trying to get answers there as well. I haven’t been successfully able to wean from Medrol and I suspect IVIG might be helpful but I don’t have a diagnosis that would warrant it, so it feels like I’m on this hamster mill of cycling on and off different drugs. I begin my 8th biologic on Wednesday. I’m ever hopeful! Thank you for responding 🙂

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Are you taking any medications? I was on a medication that caused constant nausea and occasional vomiting. Once I got off it I felt so much better. I lost weight and just felt unwell. It was awful so I can sympathize.

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