Metoprolol: Are you experiencing side effects?

I take metoprolol 50 mg twice a day. I am soo tired. I force myself to be active. I started camzyos 4 weeks ago. I have Obstructive HCM gradient of 199. My heart was fluttering a lot before moving my dose from 50 mg once a day to twice a day. The flutter and chest pain seem to be stress related. Taking lorazepam, trazedone etc. doesn't help the fatigue. I have an echo and see my cardiologist tomorrow. I'll bring it up then. If anyone knows of a reasonable alternative, let us know.

I was on 25mg time release once daily and was told to take a night so that I wouldn't get sleepy. I have a lot of fatigue and my BP is normal on this med, it was high without it, but my heart rate was consistently 45-55 during the day. I was told to cut in half to 12.5mg at night to see if I still have fatigue. BP is normal still, sometimes gets a little higher. But my heart rate shuffles between 45-55 at rest and 70-110 at rest during the day. I was told to experiment not taking it to see if the fatigue goes away because they'd switch me to a different medication if so since they are trying to get my heart rate to around 60bpm. My obstruction is worse with exercise and with my low bpm on even 25mg metoprolol, they can't increase my metoprolol. I'm seeing a new cardiologist in June so hoping to get a better plan for myself.

I was on Verapamil before a septal myectomy and have been on Metoprolol 50 mg SUCC ever since the surgery with no noticeable side effects. I realize those in the discussion have not had surgery, but I would like to suggest discussing calcium blockers vs beta blockers with your cardiologists. You may want to read https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/beta-blockers/art-20044522 and https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/calcium-channel-blockers/art-20047605 to get an informed background leading into a discussion with your cardiologist.

Thanks @walkinggirl The med that my current cardiologist was thinking of switching me to is a Calcium channel blocker, Diltiazem. I'm waiting 3 weeks to speak to my new consult who is within Kaiser (for those who follow my Kaiser Permanente story), but came from Stanford. The HCMA was really helpful in sorting out who I should see at Kaiser.

That’s interesting. I was also told to split the 25 mg Tartrate 1/2 in am and 1/2 in pm. But not sure why.

I am 78 and take 25 mg in the morning. Should I take it in the evening? I take alot of meds and I am tired most of the time.

After reading these comments I'm wondering if this is part of the reason I feel tired all day long. I take 1/2 in the morning and 1/2 at night. I believe it's 25 mg per pill. I've been on it for 2 yrs. There has also been a lot of stressful things happening in the last 2 yrs. I just attributed it to that, but now I'm wondering.

I take 50 mg in the morning. (It's considered a 24 hr tablet)
Everyone is different. Check with your Cartiologist.

Yes, it seems that @jachrist and I are both taking 50 mg Metoprolol Succinate, which is supposed to dispense over a period of time rather than in one "burst" as the tartrate is dispensed. That's what both the Mayo PA and my home cardiologist said when I was experiencing a surgery side effect, and I was switched from the tartrate to the succinate version. BTW, in my case, I do not think it made any difference, the side effect was from another cause. Mine is prescribed to take in the morning. By 3 or 4 in the afternoon I am feeling a bit fatigued, so I plan my day taking that into account.

Sorry to hear you’re having side effects. There is another class of drug called calcium channel blockers, which are used to control rate also. You may want to mention this to your physician to see whether it would be appropriate to change meds.