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Pain in leg muscles, tendons, and knees after Bilateral PE on Eliquis

Posted by smasneri @smasneri, Jul 6, 2023

One month after massive bilateral PE and taking 5 mg twice daily. Experiencing constant and continual pain in legs, mainly behind both knees, in tendons, and some muscle flare ups. Have had two ultrasounds and a CT scan on both legs since I was diagnosed June 6 and they are negative. My D Diemer is .43 and all vitals strong and regular. Echocardiogram shows no strain on heart. We have ruled most everything else out. No trauma to legs, no cuts, bruises or strains. Is this related to the Eliquis? My local hematologist wants me on it for another 5 months, I won’t be able to make that unless this subsides. Anyone else out there having this issue? Recommendations?

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petergrasser | @petergrasser | 2 days ago

I have the same issues never had well joints or pain before taking eliquis

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edv | @edv | 2 days ago
In reply to @suitstiffany "I have been on elquis for almost 2yrs due PE. I am very active person. I..." + (show)
@suitstiffany

I have been on elquis for almost 2yrs due PE. I am very active person. I use to participate in tri races and running events. Since I have been on this medicine I have had continued muscle weakness especially on the right side leg. Currently in Pt for torn mensicus. I have developed muscle spasms in my left foot to where my toes will stretch out as far as they cab before relaxing. Hurts something awful. My I teach swimming and having trouble keeping up with my clients. I keep asking the doc if I can reduce the med or something. I just have chronic muscle weakness in my right leg and my lower back hurts right around the si joint. Im so over it and the pain especially towards the end of day
I miss running. I can still bike and swim but those are getting harder to do. This muscle weakness is no joke when one spends their lifestyle trying to do right with their body.

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Your comment are very interesting. Since starting Eliquis I have developed significant joint pain with the worst being hands/wrists and neck plus feeling ‘off’ in the mornings in particular. As the day goes on I get better but still have pain. The marker for inflammation also has gone way up along with my WBC. Haven’t yet spoken with PCP and cardiologist about it but will be soon. I dint feel like working out and I know I could not lift weights of any weight so getting weaker.

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petergrasser | @petergrasser | 1 day ago

I’m feeling the same. Have a referral to a cardiologist and will update

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ruth36 | @ruth36 | 1 day ago

I’ve been taking Eliquis since January and I noticed around a month later started having issues with my leg being stiff. my knees hurting when I bend them. It seems like it’s affecting my right leg worse I’m having issues trying to do anything around the house or in the yard now…I have to use a cane when I’m walking around the house and in the yard now. I’ve also started to get cramps in my ankle and foot at night…I’m wondering, after reading some Posts here if it could be the Eliquis.

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megan1853 | @megan1853 | 1 day ago

On Eliquis 5mg twice a day and pain behind one knee is substantial. Hard to walk when arising from bed, couch, driver’s seat, and chairs even if leg had been elevated. Last ultrasound showed DVT has cleared. Don’t know why such pain—total disruption to daily life.

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