New antidepressant: Has anyone tried Auvelity?

Posted by csmiller @csmiller, Oct 26, 2022

Anyone know the name of new antidepressant, approved by FDA, that's supposed to be available at end of this year?

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Profile picture for audame @audame

Just started auevelity after trying many other antidepressants. I am running out of hope. I have been on it almost Two weeks and read that it could kick in in a week. Maybe I just got my hopes up. Does anyone know when the sleepiness side effects go away. I have many of the other side effects but it’s too early to give up
How long did it take to kick in for you??

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I have been on Auvelity for just over four months. I did not experience drowsiness in the beginning. I got an immediate bump of motivation to do things. About six weeks in, it really started to improve my mood and motivation to do things. I didn't want to stay in bed and if I wasn't doing something I got fidgety. That was awesome for me!

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Profile picture for audame @audame

Just started auevelity after trying many other antidepressants. I am running out of hope. I have been on it almost Two weeks and read that it could kick in in a week. Maybe I just got my hopes up. Does anyone know when the sleepiness side effects go away. I have many of the other side effects but it’s too early to give up
How long did it take to kick in for you??

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I appreciate your post. I've been dealing with depression for years.
I've was taking Auvelity for more than 2 weeks (maybe 16 to 18 days) and I could tell no difference in the depression. NONE.
However, the side effects for me was sleeplessness. It disrupted my sleep. It was so unpleasant that I had to stop taking it.

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Has anyone tried Auvelity? I know it is for Major Depressive Disorder (which I have) but I also suffer from Generalized Anxiety Disorder and Panic Disorder. Has anyone had any luck with Auvelity treating not only their depression but also their anxiety?

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Profile picture for ellemccope @ellemccope

Has anyone tried Auvelity? I know it is for Major Depressive Disorder (which I have) but I also suffer from Generalized Anxiety Disorder and Panic Disorder. Has anyone had any luck with Auvelity treating not only their depression but also their anxiety?

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I tried Auvelity and it seemed to help for a few weeks. But I got insomnia and then super bad headaches with nausea so now I’ve discontinued.

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Profile picture for missylv @missylv

I tried Auvelity and it seemed to help for a few weeks. But I got insomnia and then super bad headaches with nausea so now I’ve discontinued.

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Oh, I’m so sorry to hear of your bad experience with Auvelity. I’m very hesitant to take it for fear of side effects and for fear that it will not address my Generalized Anxiety Disorder.
I hope you have found a medication with more tolerable side effects or, hopefully, without any side effects.
Take care and thank you for responding so quickly to my question.

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Profile picture for ellemccope @ellemccope

Has anyone tried Auvelity? I know it is for Major Depressive Disorder (which I have) but I also suffer from Generalized Anxiety Disorder and Panic Disorder. Has anyone had any luck with Auvelity treating not only their depression but also their anxiety?

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I suffer from major depressive disorder and panic disorder and have been on Auvelty for about a month. Around week two, it seemed to help in that I was more resilient, but it hasn’t helped mitigate my depression or anxiety. I should also add that nothing has helped me, I’ve tried every medication and treatment possible, so don’t let my experience discourage you from trying Auvelity. I know it has helped quite a few people and it’s the fastest acting anti-depressant available - I would also add that I have not experienced any noticeable side effects from being in Auvelity. My doctor plans to keep me on it at least for the time being. Hope this helps even if a little bit!

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Profile picture for trocano @ctrogan

I suffer from major depressive disorder and panic disorder and have been on Auvelty for about a month. Around week two, it seemed to help in that I was more resilient, but it hasn’t helped mitigate my depression or anxiety. I should also add that nothing has helped me, I’ve tried every medication and treatment possible, so don’t let my experience discourage you from trying Auvelity. I know it has helped quite a few people and it’s the fastest acting anti-depressant available - I would also add that I have not experienced any noticeable side effects from being in Auvelity. My doctor plans to keep me on it at least for the time being. Hope this helps even if a little bit!

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Thank you so much for replying to my post. It was very kind of you.
I’m sorry you haven’t experienced any noticeable improvement in your depression and anxiety, thus far, since starting the Auvelity. Hopefully, it will improve. If not, please continue to try other meds or treatments and be proud of yourself for your strength, courage, and fortitude as you try each new medicine or treatment.
I’ve decided to try Pristiq instead of Auvelity. Today is my first day on the Pristiq — hoping it works because I, too, have tried numerous meds and treatments without any success, except for Zoloft which eventually stopped working.
I wish you all the best. Know that you’re not alone and we will find something that works for us!

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Profile picture for ellemccope @ellemccope

Has anyone tried Auvelity? I know it is for Major Depressive Disorder (which I have) but I also suffer from Generalized Anxiety Disorder and Panic Disorder. Has anyone had any luck with Auvelity treating not only their depression but also their anxiety?

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Thank you for your kind words, I never thought I’d be at this place - without a single advocate to help me with my lifelong struggle through depression. Only people who deliberately misunderstand what it’s like….every day is hell, I can’t sleep because I dread the next day, cycle after cycle. And no one cares. People are tired of me and have become desensitized, I’ve withdrawn further and the cycle keeps going. I wish you all the best. It honestly sounds like you have more options that I do. Keep pursuing them. I know how hard it is. Keep going as long as you can. If only some people knew what we did just to put one foot on the ground out of our bed each day. It can be like climbing Mt Everest to the top.

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Profile picture for ellemccope @ellemccope

Has anyone had success using Auvelity to treat anxiety? I have MDD, GAD, and I suffer from panic attacks. I was on Zoloft for 25 years, but it stopped working around the time of the pandemic. Since then, I’ve tried nearly every antidepressant and anti-psychotic available, but I’m treatment resistant — mostly because I can’t tolerate the side effects or the meds simply don’t work for me. The only thing that has helped somewhat is Mirtazapine (Remeron), but it only helps somewhat with the depression and doesn’t help with anxiety at all. My psychiatrist has suggested Auvelity; so, I just want to know if it has helped anyone with their anxiety.
Thanks so much!

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I am also drug resistant.
I am going to be trying TMS.
Read about it online, very interesting procedure.

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Profile picture for ellemccope @ellemccope

Has anyone tried Auvelity? I know it is for Major Depressive Disorder (which I have) but I also suffer from Generalized Anxiety Disorder and Panic Disorder. Has anyone had any luck with Auvelity treating not only their depression but also their anxiety?

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I feel really good on Auvelity, but wow the daytime sleepiness is intense. Anybody else get that? Snooze snooze snooze. I just started Auvelity 6 days ago when I started sessions with a psychiatrist, finally. Wish I'd connected with one sooner. I don't talk to any of my loved ones about this kind of thing. I'm 71, just trying to live my best life.

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