Any opinions about Zoloft or Sertraline?

Both meds helped me tremendously. First was prescribed Sertraline which did work great, but literally killed my appetite and I couldn't eat. (Dry mouth, can't swallow type thing) Because of this, I was switched to Zoloft which I have been taking since my daughter was born in 2019. I am also one who does not like taking meds/ does not like having to depend on them, but I have stopped a couple times and each time I went back to a very depressed state. After this last time, I have decided that I can no longer function without them. I am still depressed at times, but not feeling absolutely hopeless or suicidal thoughts.

You definitely want to out-weigh the cons vs benefits. For me, the benefits far out-weigh my want to be medication free. I am a happier person for myself and for everyone around me.

I thought Sertraline is Zoloft?

I thought Sertraline is Zoloft?

I have been on sertraline for depression for 20+ years and for the last 2-3 years have been experiencing extreme fatigue, lack of motivation. I get 8-9 hours of sleep each night but wake up tired. My doctor suggests adding Wellbutrin with Sertraline or just switching to Wellbutrin alone. We have been decreasing my Sertraline dose but no changes noted in my fatigue. I’ve been on Sertraline so long and am a bit anxious about adding another medication. Struggling on what to do.

@blt50
I take 75 mg of sertraline (Zoloft) and 300 mg of Wellbutrin/bupropion and it is a good combination for me. Many call this combination “Welloft” since it really helps them.

If you start low on Wellbutrin/bupropion to try to see if it helps, you may find it does work for you. It does not cause me any side effects and it is the only combination that has worked for me for deep depression, low energy, low motivation, etc. it takes time to find the right medications that work for each person so be patient and work closely with your doctor.

Have you been tested for sleep apnea with a sleep study? When you wake up tired after sleeping 8-9 hours, it was a sign for me I had sleep apnea (moderate). I use a cpap now and I don’t wake up as tired anymore.

I have been on sertraline for depression for 20+ years and for the last 2-3 years have been experiencing extreme fatigue, lack of motivation. I get 8-9 hours of sleep each night but wake up tired. My doctor suggests adding Wellbutrin with Sertraline or just switching to Wellbutrin alone. We have been decreasing my Sertraline dose but no changes noted in my fatigue. I’ve been on Sertraline so long and am a bit anxious about adding another medication. Struggling on what to do.

I have been on sertraline for depression for 20+ years and for the last 2-3 years have been experiencing extreme fatigue, lack of motivation. I get 8-9 hours of sleep each night but wake up tired. My doctor suggests adding Wellbutrin with Sertraline or just switching to Wellbutrin alone. We have been decreasing my Sertraline dose but no changes noted in my fatigue. I’ve been on Sertraline so long and am a bit anxious about adding another medication. Struggling on what to do.