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Perindopril for BP is now giving me foot and leg swelling
I was put on Coversil 4 (perindopril) 10 years ago when my BP was going up to 180 - 190. That kept my BP at around 140 although The dosage needed to be increased periodically to keep achieving this BP.
When the dosage was eventually increased to 10 mg, I started getting constant foot and leg swelling and BP that tended to often be up to 190 by mid 2024.
A GP added a sulfa diuretic in mid 2023 but I had side effects as I am allergic to drugs with sulfa. A new GP again tried to add a sulfa diuretic early in 2025 and I ended up not taking it and my BP climbed to 170 - 190 and my feet and legs remained very swollen with pitting oedema . Then, in mid 2025, this same GP put me on a combined tablet (Coveram) of 10 mg of perindopril plus 5 mg of amlodipine. Subsequently my feet and legs remain very swollen and my BP now varies from the low to high 100s.
This GP now wants to prescribe the sulfa diuretic again.
I have three main questions:
1. How do I stop doctors ignoring my allergies (mainly NSAIDS) and sulfa) despite my notifying them of this?
2. Why do doctors keep wanting to add a diuretic and not just take me off medications with perindopril?
3. Why am I being made to continue to have high BP and oedema (and now this unusual variable BP)?
Fortunately my heart is fine. I have had a couple of echo scans and no problems were found.
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See a Cardiologist that has a lot of experience. I reduced my blood pressure by not having any processed food at all. NO salt in my food at all (tasteless but healthy). I take walks 2 to 3 miles per day. I lost 20 pounds in 8 weeks and now my BP is 130/84. I hope this helps.
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1 ReactionI did the same, went on a low carb diet, lost 22 pounds (I'm not a large man, under 5' 9", so that was a chunk o' weight for me), but I have been active on my feet for decades. I still walked or ran for between 10-22 km each day, or maybe five days each week. So, I can vouch for changing habits as a potential cure for heart problems.
However, it was really the undiagnosed sleep apnea that was most of the problem for me. Weight, yes, and the cardiologist I saw about my fibrillating heart put me on metoprolol for two reasons: incipient hypertension and to control my rapid atrial firing when my heart decided it was cranky enough to want to fibrillate. The problem, the trigger, for the cranky heart, though, was sleep apnea. In my case, the polysomnography results was a devastating 'severe obstructive sleep apnea.' And I couldn't be called 'overweight' back when this happened....the weight gain came subsequently when I felt I couldn't risk taxing my heart with aerobic running.