Getting off of Seroquel

Posted by anniegk @anniegk, Jun 8, 2018

I have been on 300 mgs. Seroquel ER for over a year for augmenting my antidepressant which is 45 mgs. Of Mirtazapine. I decided to try and get off of the Seroquel. I was on 300mgs ER (extended release). I titrated down to 250 mg ER for 2 months without too many problems.than i titrated down to 200mgs ER just 5 days ago. My plan is to try to titrate off using ER tablets. My thinking is that perhaps the drug will remove its self from my system more gradually. I have had some nausea and a couple of episodes of diarrhea. I also have a very irregular heart beat and was started on 60 mgs of Propranolol ER (extended release) 4 weeks ago. It seems to be helping my heartbeat. I have wondered if the nausea and light headness is from the Propranolol, a Beta Blocker, or the dose reduction of the Seroquel. I also wonder if the way iam titrating the Seroquel is safe. My doctor says it will only take a couple of weeks...I think that is too fast of a taper after being on a drug for over a year. What do you think?

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Profile picture for kathee007 @kathee007

Hello

I am presently taking 150 mg of Seroquel at night along with 7.5 mg of Remeron and 7.5 mg of buspirone. I take 50 mg of Seroquel in the morning. I would like to wean off of Seroquel since I am experiencing malaise, confusion, brain fog, difficult with focusing my eyes and other issues. What would you suggest for a weaning schedule for the Seroquel?

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Wean off but notify your provider

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My wife started Seroquel for insomnia. It made it much worse. She has taken 50 MG per day. For only 3 days. Can she stop this cold turkey after this short time on the drug? If not, how would you taper down.

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Profile picture for jonp52 @jonp52

My wife started Seroquel for insomnia. It made it much worse. She has taken 50 MG per day. For only 3 days. Can she stop this cold turkey after this short time on the drug? If not, how would you taper down.

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She can just stop in my opinion. And only took a total of 150 mgs. She’ll be fine.

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Hi.
After a year taking Seroquel 50mg every night I’ve noticed some swollen looking on my face so I decided to stop at once. I’ve been dealing with sleeping problems since I stopped 3 days ago and I hope these eventually disappear. My concern is the facial swollen appearance and light weight gain… would these eventually disappear too? Thanks.

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Yeah, I was on it for at least a year although I don’t remember the dosage. It helped my sleep incredibly. The combination of antipsychotics with SSRI’s is a good one if you can tolerate the side effects. Unfortunately, I developed Tardive Dyskenisea, those weird mouth movements/grimacing. I didn’t even know it until I saw myself on a Zoom recording and was shocked. I then had to decide between being able to sleep or the TD. Man it was a toss up. I even tried Ingrezza which is a new med specifically manufactured for TD. But that made me incredibly dizzy which was scary. So I finally got off the Seroquel, but it took over a year for the TD to stop and I actually thought I had the TD permanently. It really made me cry. 😢

Have now been taking Ativan with Vistaril but I’ll be the first to admit that I abused the Ativan because it also helped my headaches. So this has been unsuccessful because then I run out of the Ativan too early and then have worse insomnia, as in I might sleep once every 3 days. It’s a fricking battle. I’m seeing a new psychiatrist today. I am praying he can help me. My current psychiatrist is good but I see him as part of a university college and that means I have to see a new one every year and that really sucks big time. So, all I can say after 45 years of this crap is hang in there baby!!!

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Profile picture for Lisa Lucier, Moderator @lisalucier

Hi, @anniegk — I apologize for not responding earlier, but somehow I missed getting a notification about your post! I'm wondering about how your taper off of Quetiapine (Seroquel) has been going.

I'd like to invite @derryman @IndianaScott @loveallmyboys @whereveryougothereyouare @tib85 @giacamosgirl58 @majic @hwilson7 @resolve @ronlin1948 @ginak523 and @cathy615 into this discussion to share their thoughts and experiences with Quetiapine (Seroquel)and tapering, if that applies. @gailb and @gman007 may also have some thoughts about the journey going off this medication and the side effects you've experienced.

You mentioned taking Quetiapine (Seroquel) in addition to Remeron (Mirtazapine) and then deciding to try and get off the Seroquel. Curious about what made you want to discontinue the medication? Were you having unpleasant side effects?

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Hi , I am switching anti depressants but taking 50 mg of seroquel the last month. I feel like ampm getting worse. Wake up anxious everyday, the Ned only gets me 5 hours sleep anyway, I told my dr. She told me to get off it

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Hi. Is there anyone there

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Profile picture for billheenan @billheenan

Hi , I am switching anti depressants but taking 50 mg of seroquel the last month. I feel like ampm getting worse. Wake up anxious everyday, the Ned only gets me 5 hours sleep anyway, I told my dr. She told me to get off it

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Sorry for the typos!

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Profile picture for hopeful123 @hopeful123

I have gotten off 600mg Seroquel but not the XR. It was being used to help me sleep probably anti anxiety as well. It was tough and took about 6 months but I have been off it about 6 months now. Tons of nausea when I went off it but my doctor explained it absolutely is normal because it does work on some sort of anti nausea brain receptors. I got down to 25mg then stopped. I’m still completing a benzodiazepine taper but I am glad I got off the Seroquel as it fogged my thinking.

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Hi I know this was a number of years ago now, but I was wondering how you went with insomnia and muscle twitching?

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