Is anyone taking repatha

Curious, have they checked your parathyroids and thyroids?

Thyroid is good. I will ask my PCP about parathyroid tests. Why are you asking? Any relation to lipids?

I took 9 shots of Repatha @naiviv . It only dropped my LDL about 15% and I experienced increasingly intolerable side effects.

I have some similarities with @vaniag and am curious. Repatha works well for my dad, too. I think his LDL got as low as 8 on Repatha. My LDL goal is 55, same as yours and it is currently 88. You mention modified Mediterranean diet. Would you elaborate? What drugs are you taking? I do have FH but do not have elevated LP(a). What is the Horizon trial? Like you, I am in a place of doing all I can. It’s a good place to be.

I have been doing the Mediterranean diet for quite awhile and it has worked greatly. Lost 30 pounds since Dec 2023 and keeping my weight. Don’t eat desserts only z piece of dark chocolate now and then but not much so far. No red meat at all. Only fish, chicken and turkey. Veggies/salad/legimes/beans and fruits. No soda at all. I don’t drink or smoke. I take Levoxyl for Thyroid. My labs have been excellent. I don’t get Repatha; I asked for my husband who started it last week. I take Metformin for pre-diabetes (my parents suffered from late-onset diabetes at age 79/84. My glucose has been low thanks to diet, exercise and med. I don’t know what is the Horizon trial.

Sorry to hear Reaptha didn’t work for you. It took me 3 months to stop having mild side effects. Not fun, but it was my only solution for high cholesterol. I had issues with every statin and even Zetia.

I have Celiac Disease, so no gluten…but I also do not tolerate dairy, shellfish or eggs. So basically I modify the Mediterranean Diet to all my food issues. Lots of veggies, poultry and fish. I also keep carbs to a minimum.

I take Repatha and Nexletol. Nexletol is bempedoic acid…a precursor to where statin drugs impact the liver. Nexletol has been great - no side effects at all but it doesn’t lower LDL as much as statin. My insurance hates the combo…very expensive.

The Horizon trial is for people with high Lipoprotein(a) and heart or vascular disease. I had a heart attack 5 years ago, so when the docs found my Lp(a) was over 300 nmol, I was eligible for the trial.

Some researchers found that Repatha sometimes doesn’t work well for women. Works great for my mother so not sure why not for me. They will figure it out one day. My PTH and thyroid are fine…probably something else in the liver. We forget cholesterol is a liver disease that affects the heart.

So good to connect with all of you. Heart disease really “sucks”. I did everything they tell you to avoid it…sometimes those genes win.

Life is good. 😊

It seems you have tried everything but at least something is working. Stay healthy and safe. Thanks

The best

Parathyroids have a major impact on calcium in your system. If you go on the mayo clinic website and do a search, it will explain the interaction of the parathyroids and calcium and cholesterol.

Great. I will. Thanks

What was your Lp(a)?
Did that come down too?