Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Have you ever done anything that started out great, but after a while didn't work as well, but you continue in the hope it will improvel?

After new and increased pains after each of my 16+ ortho surgeries, with various autoimmune diseases, AND advancing age, I still thought it might be helping somewhat. It wasn't until talking to others about their experiences and research that I realized the cognitive decline, changes in affect, weight, and eventual tooth loss were likely attributable to the drug. They resolved -- obviously not tooth loss - once off the drug.

Robert why such an angry, blaming reply to my personal account in response to a question?

i was not piling on. nor calling you stupid. i just can't figure out why you would go so long before you take matters into your own hands and stop taking this med. of course they react differently. no 2 people are the same. that's why i advocate on researching meds. stop being offended if i question you. i'm not attacking you. everybody needs someone who cares enough to question choices. i know i sure do. it helps us from being harmed by doctors. and i always say "if the doctor don't do right by you. fire them." find a doctor who'll help you.

i must have a different tolerance level for drugs. than some people. i'm on 120 mg of Cymbalta and 2400mg of Gabapentin. a day each. i don't have side effects. from either nor combined. i don't get loopy nor mellow. but sometimes i wish it did. especially loopy. just me. plus 100 mg of Celebrex a day. for a Herniated disc @ L4- L5. 🤷‍♂️🤷‍♂️.
but i'm thrilled it helps with your pain, @cantab. Daniel

I have been on Lyrica before. Had to get off of it because it affected my memory and sent me into a very bad depression. My psychologist requested I get off Lyrica because of these side effects. Please be careful on Lyrica
Lyrica was the best thing I’ve taken for my neuropathy pain but can’t handle the side effects.

It was suggested i try cymbalta for my pain, which i think is a side affect from ECT treatments.(electro convulsive therapy) I get very sharp pains in my toes or anywhere in my body. My feet are very sore, I am very dizzy. I need a refferal from one of my doctors to get a MRI. These symptoms have been ongoing for months

Yes, I have been taking it for 3 years. I had a pinched nerve in my neck. I had therapy...no help. I wore a neck brace for 1 and 1/2 years. It helped but I didn't want to wear it forever. Dr. Ordered Duloxitine. After a week or so all neck pain was relieved. It was wonderful. Still taking 30 mg every day.

Lyrica is just a neuropic pain reliever like neurontin (gabapentin) it blocks the pain ex: in the nerves in your feet. You don't or shouldn't have any pain with touch, walking etc. lyrica works for some people and not for others and the same thing for neurontin.

I didn't even think they made celebrex anymore but please, and I'm sure you are but, please eat something when you take your meds
Mom and R. N coming out in me sorry.
Meds are like that for me as well. I have the opposite effect

@danny5 @mskow Medications build up and you have to maintain a certain level in your body especially when you have been taking it for so long. And if we are compliant with what our Dr says, then hey the Dr knows best right? 20 years on a medication the level which is in his body, he absolutely has to medically taper off of it and it is not a easy process to go through the situation at all. If you look at the recall of cymbalta that is going on right now and what they recalled it for!
You can get addicted to cymbalta and being on it for any amount of time and trying to get off a high dose you withdrawal. Sweats, diarrhea the whole thing. They can try and give you another antidepressant to help with the suicidal thoughts.. you can go to rehab. What this man went through i praise you sir and I'm proud of you!
I was on cymbalta but I don't remember the reason why I was taken off and changed to my current medication which is effexor xr, I was on Ability and I was taken off of that because I had a tic from it and didn't even know it haha. My med doctor is who noticed it. As a nurse I personally know your situation and you made it through that chapter and, you have many more chapters to write in your book. Be proud of yourself and tell YOUR story because it's just that YOUR story to tell and no one else can edit it for you or white any of it out. Be so grateful, appreciate everyday, and know that you did it for yourself, nobody else did. I'm proud of you and don't let anyone dull your shine darlin!

@KarlosWaterman have you tried Botox injections through a neurologist? I get 43 tiny injectors every 91 days because of my migraines and he also does the injections in the jaw hinge, it's not even half as awful as it sounds trust me. And not Botox that is for cosmetic reasons. But after the 2 series of the injections is when I started to really notice the change with my TMJ and my migraines were less. Just a suggestion