ARINA-1 Clinical Trial with nebulized solution-NO ANTIBIOTICS

GOOD NEWS!!!

We have been asking for bronchiectasis treatments that are not antibiotics, and we have been heard!

Dr. Charles Daley is a well-respected expert from National Jewish Health in Denver. He was a keynote speaker at the World Bronchiectasis Conference and gave the closing remarks.

Dr. Daley is also the principal investigator of a study evaluating ARINA-1, a nebulized solution manufactured by Renovion that has been shown to prevent mucus from clogging our airways. Clogged airways cause inflammation and infection, a cycle we try to break with daily airway clearance and, often, antibiotics.

ARINA-1 is a sterile formulation that is manufactured under strict guidelines. The solution includes glutathione, ascorbic acid, and a buffer to modify the pH.

The trial will measure ARINA-1’s impact on quality of life, mucus viscosity, and inflammation.

Researchers are looking for 25 more participants for the 28-day study. Participants need to be diagnosed with non-CF bronchiectasis and have mucus. In addition to National Jewish in Denver, trial sites are located in Baltimore; Philadelphia; Seattle; Birmingham, AL; New Orleans; Tyler, TX; Winston-Salem, NC; Portland, OR; and Charleston, SC. If you live in or around one of these areas and are interested in the trial, let me know.

Click on the following link to clinicaltrials.gov for more information on the ARINA-1 trial.
https://tinyurl.com/tsh6fjnr
I am working with Renovion and researchers to share this opportunity, and I can help answer basic questions regarding:

-Participating doctors
-Laboratory studies of ARINA-1
-How nebulizing this solution differs from nebulizing glutathione alone or orally administered NAC
-The importance of the combination of glutathione and ascorbic acid

If you have other questions about the trial, the drug or how to enroll, let me know and I can help you get an answer from the Chief Scientific Officer at Renovion who is a great resource.

Most importantly, discuss this trial with your doctor.

Dr. Daley implored us to get involved in bronchiectasis and NTM research. Let’s show him and the researchers working on our behalf that we are willing to participate whenever possible.