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Comments (668)

I'm glad Lyrica and Cymbalta are working for you as I've read they only work for...

https://connect.mayoclinic.org/comment/886860/

I'm glad Lyrica and Cymbalta are

Discussion: Fibromyalgia -- Need help on how to handle severe pain

Support Group: Fibromyalgia

Posted: Jun 28, 2023

@annatino Since 2006, a life-long consequence of chemotherapy is residual peripheral neuropathy. Having tried gabapentin, Lyrica,...

https://connect.mayoclinic.org/comment/719416/

Having tried gabapentin, Lyrica, pristiq ... , cymbalta, etc. ...none of them gave

Discussion: Is it safe to stop gabapentin? How?

Support Group: Neuropathy

Posted: Jun 20, 2022

That’s wonderful news that it works. I want to emphasize that between Lyrica and Cymbalta, many...

https://connect.mayoclinic.org/comment/767223/

I want to emphasize that between Lyrica ... and Cymbalta, many people ARE helped ... the time, after losing so much with Cymbalta

Discussion: Has anyone had experience using cymbalta for pain relief?

Support Group: Chronic Pain

Posted: Oct 30, 2022

I have suffered with this for years. While the pain feels like it is in the...

https://connect.mayoclinic.org/comment/821510/

Lyrica and Cymbalta help a great deal

Discussion: What helps to relieve pain in my butt?

Support Group: Bones, Joints & Muscles

Posted: Mar 6, 2023

Iv e been a diabetic for about 15 years. Sugar stayed constant till 2014 when I...

https://connect.mayoclinic.org/comment/314534/

On lyrica and cymbalta for neuropathy

Discussion: Buerger's disease and diabetes

Support Group: Diabetes & Endocrine System

Posted: Jun 22, 2020

I had my gallbladder removed 8 years ago, 2 or 3 small incisions. I had a...

https://connect.mayoclinic.org/comment/808940/

I take Neurontin and have taken Lyrica ... and Cymbalta with no help at all.

Discussion: Post-cholecystectomy or gallbladder removal surgery

Support Group: Digestive Health

Posted: Feb 9, 2023

I have been on gabapentin for almost 15 years now. At my initial diagnosis of IPN...

https://connect.mayoclinic.org/comment/1073878/

I have tried Lyrica and cymbalta but

Discussion: Gabapentin side effects?

Support Group: Chronic Pain

Posted: May 24, 2024

Hello, I’m new here and happy to have discovered it. I am on my first week...

https://connect.mayoclinic.org/comment/1018991/

I do not do well on Lyrica or Cymbalta

Discussion: Gabapentin side effects?

Support Group: Chronic Pain

Posted: Feb 20, 2024

Chronic myofascial pain syndrome is one option doctors should consider. Mine developed gradually following the two...

https://connect.mayoclinic.org/comment/1474826/

I take Lyrica and Cymbalta and get some

Discussion: Rib cage pain. Er docs don’t know what’s wrong with me

Support Group: Chronic Pain

Posted: Jan 5 6:39am

@sandytoes14 Hi Jen yes Dr had me on Lyrica helped by taking 2different dosages One for...

https://connect.mayoclinic.org/comment/209086/

sandytoes14 Hi Jen yes Dr had me on Lyrica ... then the pain got so bad ,not from Lyrica ... ,then Cymbalta I had a bad reaction ... to Cymbalta ,mentally all this scared ... not gone and I did gain weight on Lyrica

Discussion: Anyone take Lyrica for fibromyalgia and pain?

Support Group: Fibromyalgia

Posted: Jul 19, 2018

I have tried the medical marijuana it intensifies my numbness no relief from the burning. I’m...

https://connect.mayoclinic.org/comment/240894/

medicine put me on the treatment with lyrica ... gabetin cymbalta I was on 1800 MG of ... I was on 600 MG of lyrica that did nothing ... and 30 MG of cymbalta and 35 MG of

Discussion: Small Fiber Neuropathy: What helps?

Support Group: Neuropathy

Posted: Jan 22, 2019

If you do an on-line search you'll find many articles about drugs for fibro. Harvard Health...

https://connect.mayoclinic.org/comment/992445/

fibromyalgia, including pregabalin (Lyrica ... ), duloxetine (Cymbalta), and milnacipran

Discussion: Will you listen?

Support Group: Chronic Pain

Posted: Jan 6, 2024

I have chronic pain under my ribs, front and back, that was finally diagnosed two years...

https://connect.mayoclinic.org/comment/1466250/

I am treated with Lyrica and Cymbalta

Discussion: Pain under ribs for 9 years

Support Group: Chronic Pain

Posted: Dec 23, 2025

I don’t know where you are located in Chicagoland but I recently transferred to Dr. Lubenow...

https://connect.mayoclinic.org/comment/804752/

that didn’t work out so I’m back to Lyrica ... , Hydrocodone, Cymbalta.

Discussion: Anyone been diagnosed with arachnoiditis after spine surgery?

Support Group: Spine Health

Posted: Feb 1, 2023

Is this your opinion or Mayo’s—not trying to be smart either—talked to Charlene(believe that was her...

https://connect.mayoclinic.org/comment/335206/

willing to take the time to run it down)—lyrica-gabapentin-cymbalta

Discussion: Has anyone used MLS Laser therapy or Calmare Therapy?

Support Group: Neuropathy

Posted: Feb 17, 2021

Hi up until 16 months ago. I was an avid walker, loved wooout and the outdoors....

https://connect.mayoclinic.org/comment/1015334/

I do not want the Gabapentin, Lyrica ... , or Cymbalta.

Discussion: Chronic Pain members - Welcome, please introduce yourself

Support Group: Chronic Pain

Posted: Feb 13, 2024

I was diagnosed with Myofascial Pain Syndrome in June 2025 by a rheumatologist in conjunction with...

https://connect.mayoclinic.org/comment/1459022/

It, along with Lyrica and Cymbalta,

Discussion: Myofacial Pain Syndrome

Support Group: Chronic Pain

Posted: Dec 12, 2025

@leemayle I was diagnosed with fibromyalgia in 2012. I believe that I had it for 25...

https://connect.mayoclinic.org/comment/75400/

Savella/milnacipran, Lyrica/pregabalin ... , Cymbalta/duloxetine. ... My current regime is Cymbalta 30 mg ... once a day, Lyrica 75 mg 3x day,10mg

Discussion: Horrible leg pain with fibromyalgia

Support Group: Fibromyalgia

Posted: May 15, 2020

Hello @carolep80, Welcome to Connect. I also can't stand or walk for too long but fortunately...

https://connect.mayoclinic.org/comment/1299120/

and comments from members on your Lyrica ... or Cymbalta question - https://connect.mayoclinic.org ... search=lyrica%20or%20cymbalta You

Discussion: Need input on cortisone epidural for pain and medication for pain

Support Group: Neuropathy

Posted: May 7, 2025

Hello, I have suffered from this condition for over 2 years, and it is ruining my...

https://connect.mayoclinic.org/comment/72618/

Lyrica and Cymbalta mostly keep it at