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Comments (2,344)

Pauline...I have never been on Prednisone and have been on Methotrexate by injection once a week....

https://connect.mayoclinic.org/comment/192792/

been on Prednisone and have been on Methotrexate ... I have no idea what Methotrexate is

Discussion: PMR and Methotrexate

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Mar 15, 2018

I was on it for 6 months, home injections as well at first. I started expelling...

https://connect.mayoclinic.org/comment/1361802/

Methotrexate weekly for 2 years wasn ... The infusions are better with Methotrexate

Discussion: Actemra weekly shot vs infusions. Experiences?

Support Group: Autoimmune Diseases

Posted: Aug 1 9:44pm

Been on methotrexate along with methylprenisolone since July, 2021. My hair started thinning when the methotrexate...

https://connect.mayoclinic.org/comment/683015/

Been on methotrexate along with methylprenisolone ... My hair started thinning when the methotrexate ... realize it was the addition of the methotrexate

Discussion: Experience with Methotrexate?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Feb 21, 2022

Every morning I have hip, back an some neck pain. I’m on 5mgs of prednisone an...

https://connect.mayoclinic.org/comment/1379646/

on 5mgs of prednisone an 20mgs of methotrexate

Discussion: Anyone have discomfort or pain when tapering off prednisone?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Aug 26 9:50am

After having PMR for 3 months, was then diagnosed with RA affecting both hands. Began 8mg...

https://connect.mayoclinic.org/comment/996509/

Began 8mg Methotrexate. ... the Prednisone, then deal with the Methotrexate

Discussion: PMR Taper and pain

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Jan 13, 2024

I have been off methotrexate since June 1 because of severe dizziness which ended me in...

https://connect.mayoclinic.org/comment/1338515/

I have been off methotrexate since June ... still has dizziness after going off methotrexate

Discussion: Has anyone experienced dizziness with medication for PMR?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Jun 30 12:13pm

I got the flu shot yesterday and so far so good. Was diagnosed with PMR three...

https://connect.mayoclinic.org/comment/1401283/

Am on prednisone (15 mg) and methotrexate

Discussion: PMR and Flu Vaccine

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Sep 25 3:10pm

I’m on hydroxychloroquine, methotrexate and Humira, it works pretty well. Doesn’t touch undiagnosed neuropathy in both...

https://connect.mayoclinic.org/comment/1391525/

I’m on hydroxychloroquine, methotrexate

Discussion: Rheumatoid Arthritis (RA) - Introduce yourself and meet others

Support Group: Autoimmune Diseases

Posted: Sep 11 10:27am

@judyal I got both Covid & flu vaccines on the same day on 10/5/25. I’m on...

https://connect.mayoclinic.org/comment/1412566/

I’m on 4 mgs of prednisone & methotrexate

Discussion: PMR and Flu Vaccine

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Oct 10 10:13am

Thanks for starting this discussion @persistentc. Sorry to hear you had the PN adverse side effects...

https://connect.mayoclinic.org/comment/1257625/

had the PN adverse side effects of Methotrexate ... Potential neurotoxicity associated with methotrexate

Discussion: Excess B12 possibly causing numbness and tingling

Support Group: Neuropathy

Posted: Mar 14 8:31am

I'm on the Zoloft generic and methotrexate injections and I tolerate them well

https://connect.mayoclinic.org/comment/868684/

I'm on the Zoloft generic and methotrexate

Discussion: Do you use biologic together with antidepressant without feeling bad?

Support Group: Autoimmune Diseases

Posted: May 29, 2023

I was on 6 tabs of methotrexate once a week but rhumy increased to 8. My...

https://connect.mayoclinic.org/comment/783791/

I was on 6 tabs of methotrexate once ... not take folic on the same day as methotrexate

Discussion: Experience with Methotrexate?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Dec 11, 2022

I’m on both now for about 8 mths,I’m not finding any difference taking methotrexate,I’ve lowered my...

https://connect.mayoclinic.org/comment/872030/

not finding any difference taking methotrexate ... below 10 comfortably,I thought the methotrexate

Discussion: PMR and Methotrexate

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Jun 4, 2023

I am currently on 15 mg. of Prednisone and also Methotrexate for my PMR.

https://connect.mayoclinic.org/comment/331094/

currently on 15 mg. of Prednisone and also Methotrexate

Discussion: Anyone tried Actemra (Tocilizumab) to treat PMR? FDA approved for GCA

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Dec 30, 2020

I have to try methotrexate before I can get Kevzara or Actemra with insurance.

https://connect.mayoclinic.org/comment/1101274/

I have to try methotrexate before I

Discussion: Prednisone and methetrexate

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Jul 7, 2024

Thanks, I intend to ask my pcp about methotrexate. Not seeing a rheumatologist for a month.

https://connect.mayoclinic.org/comment/1005712/

Thanks, I intend to ask my pcp about methotrexate

Discussion: Advice/experience about going back on Prednisone

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Jan 29, 2024

Hello @mbbs, Welcome to Connect. I see that @linda7 has shared her thoughts and experience with...

https://connect.mayoclinic.org/comment/765421/

learn what others have shared about Methotrexate ... and PMR. -- PMR and Methotrexate: ... connect.mayoclinic.org/discussion/pmr-and-methotrexate

Discussion: PMR and Methotrexate

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Oct 25, 2022

I was on 15 mg Prednisone. Started on 10 mg Methotrexate 1X weekly and reduced Prednisone...

https://connect.mayoclinic.org/comment/859550/

Started on 10 mg Methotrexate 1X weekly ... real issues. 2 weeks ago, increased Methotrexate ... I thought it was the Methotrexate but

Discussion: PMR and Methotrexate

Support Group: Polymyalgia Rheumatica (PMR)

Posted: May 14, 2023

I used steroids and methotrexate over a year treating giant cell arteritis. These meds controlled the...

https://connect.mayoclinic.org/comment/957463/

I used steroids and methotrexate over ... prescribed Actemra to replace steroids and methotrexate