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Comments (2,269)

I've been on Methotrexate since 2010, and I've been on 4 different biologics. No issues at...

https://connect.mayoclinic.org/comment/319619/

I've been on Methotrexate since

Discussion: Autoimmune something: Struck with extreme fatigue

Support Group: Autoimmune Diseases

Posted: Aug 24, 2020

My rheumatologist refuses to use Methotrexate ? Wonder why? He never gave me an explanation ?

https://connect.mayoclinic.org/comment/1208081/

My rheumatologist refuses to use Methotrexate

Discussion: Using methotrexate with PMR

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Jan 10 7:23am

Methotrexate has helped with the tapering of prednisone for me. 15mg once a week. Now at...

https://connect.mayoclinic.org/comment/1005600/

Methotrexate has helped with the tapering

Discussion: Advice/experience about going back on Prednisone

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Jan 29, 2024

@quasermum thank you sharing. I look forward to hearing how methotrexate works for you.

https://connect.mayoclinic.org/comment/192809/

I look forward to hearing how methotrexate

Discussion: PMR and Methotrexate

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Mar 19, 2019

Hello, my name is Sheri and I have ulcerative colitis and RA. I am on many...

https://connect.mayoclinic.org/comment/145438/

Sulfasalazine, Methotrexate injections ... acute (occurring every 3-4 weeks) the Methotrexate ... The add of Methotrexate reduced the ... to 2 tablets 2x daily, continue the Methotrexate ... I have found some FB groups for Methotrexate

Discussion: Rheumatoid Arthritis (RA) - Introduce yourself and meet others

Support Group: Autoimmune Diseases

Posted: Jun 6, 2019

Interesting as my rheumatologist seems to think I can take covid & flu vaccines at the...

https://connect.mayoclinic.org/comment/1391135/

I just need to pause my methotrexate

Discussion: PMR Case Study with Remaining Questions as of 09-04-2025

Support Group: Polymyalgia Rheumatica (PMR)

Posted: 2 days ago

Methotrexate worked for a few months and then stopped. Taking Kevzara now and so far it’s...

https://connect.mayoclinic.org/comment/1279044/

Methotrexate worked for a few months

Discussion: Anyone having luck while taking methotrexate?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Apr 11 5:18am

Methotrexate reduced my PMR rapidly. I have only positive words fro that medication.

https://connect.mayoclinic.org/comment/831434/

Methotrexate reduced my PMR rapidly.

Discussion: PMR and Methotrexate

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Mar 24, 2023

I could not tolerate methotrexate. Have you experienced side effects from taking Actemra?

https://connect.mayoclinic.org/comment/751328/

I could not tolerate methotrexate.

Discussion: What's a good anti inflamation drug (not prednisone) for PMR?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Sep 18, 2022

https://connect.mayoclinic.org/comment/1145979/

lifeline for quite a while until the methotrexate ... that worked for me in tandem with the methotrexate

Discussion: Rheumatoid Arthritis (RA) - Introduce yourself and meet others

Support Group: Autoimmune Diseases

Posted: Sep 23, 2024

@sheetrock0131 .. I never had this until my RA doctor put me on Methotrexate. It's a...

https://connect.mayoclinic.org/comment/53064/

this until my RA doctor put me on Methotrexate ... dental work just prior to starting the Methotrexate

Discussion: Burning Mouth Syndrome. I have it very severe.

Support Group: Skin Health

Posted: Mar 3, 2018

Hello all, I am on tapering does Prednisone (5.5 daily) and methotrexate. Without the methotrexate, I...

https://connect.mayoclinic.org/comment/672047/

tapering does Prednisone (5.5 daily) and methotrexate ... Without the methotrexate, I just was

Discussion: Polymyalgia Rheumatica (PMR): Meet others & Share Your Story

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Jan 18, 2022

Hi. Sorry to hear you're having these side effects. Hopefully, your doctor told you to take...

https://connect.mayoclinic.org/comment/1286147/

acid to combat the side effects of methotrexate ... don't know if this applies to methotrexate

Discussion: Rheumatoid arthritis questions

Support Group: Autoimmune Diseases

Posted: Apr 20 1:49pm

Infusions include several drugs and this appears to affect me differently. I don't get sick. Evan...

https://connect.mayoclinic.org/comment/188495/

Evan tho Methotrexate is one of the ... The Methotrexate was so very hard on ... I stopped Methotrexate last Sunday.

Discussion: Rheumatoid Arthritis - Hope for remission? Continues to get worse?

Support Group: Autoimmune Diseases

Posted: Mar 8, 2018

I have been on 5 mg of Prednisone for over 15 years treating for general arthritis....

https://connect.mayoclinic.org/comment/1091059/

flair ups so was placed on 20 mg of methotrexate ... Like you , I thought the methotrexate ... About 6 weeks in the methotrexate kicked

Discussion: Anyone have discomfort or pain when tapering off prednisone?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Jun 21, 2024

Once you taper off the prednisone, how long will you need to be on the methotrexate?

https://connect.mayoclinic.org/comment/923324/

how long will you need to be on the methotrexate

Discussion: How to address PMR pain while decreasing prednisone

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Sep 3, 2023

Wish you well Hope the Methotrexate works out Let us know

https://connect.mayoclinic.org/comment/881011/

Wish you well Hope the Methotrexate

Discussion: Pulmonary Sarcoidosis: How are you dealing with it?

Support Group: Lung Health

Posted: Jun 19, 2023

I was diagnosed with PMR (finally) in May 2015. In May, my family doctor put me...

https://connect.mayoclinic.org/comment/1373522/

My Rheumatologist put me on methotrexate ... zero side effects so far from the methotrexate

Discussion: Using methotrexate with PMR

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Aug 18 12:36pm

Did your Rheumatologist suggest Methotrexate as an alternative while you taper from prednisone?

https://connect.mayoclinic.org/comment/1101803/

Did your Rheumatologist suggest Methotrexate

Discussion: A Bizarre Change in Condition

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Jul 8, 2024

I'm on the methotrexate 2.5= 8 tablets a week with prednisone 5.5 mg. I felt pretty...

https://connect.mayoclinic.org/comment/681332/

I'm on the methotrexate 2.5= 8 ... good, and when I went up to the max methotrexate ... back off the prednisone, and then the methotrexate

Discussion: Experience with Methotrexate?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Feb 15, 2022