Transplant

Welcome to the Mayo Clinic Transplant page! Mayo Clinic is the largest integrated transplant provider in the United States, performing over 1,500 solid organ and bone marrow transplants each year at our campuses in Arizona, Florida and Minnesota.

In these pages, there are materials for transplant recipients as well as living donors. No matter where you are in your transplant journey, our goal is to connect you to others and provide you with information and support.

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Welcome

Nearly 117,000 people in America are waiting for an organ. Unfortunately, many may never get the call saying that an organ — and a second chance at life — has been found. On average, 22 people die each day while waiting for a transplant. (Source: OPTN.)

Living donation is a wonderful act of generosity and courage, and the preferred alternative giving hope to people waiting for a deceased kidney or liver donation. It takes place when a living person chooses to give the ultimate gift of an organ donation to someone in need.

The decision to become a living donor requires time and careful consideration. Our hope is the information in this toolkit will help. If you have questions about the information provided here, please visit our Q&A tab or post a comment and we’ll get back to you as soon as we can.

Becoming a living donor

Before you decide to become a living donor, you should understand fully what donation involves. You may choose not be a donor at any time during the process. Your decision and reasons are kept confidential.

For Kidney Transplant

Most living kidney donors are a family member or friend. A donor does not need to be related to the person who receives the kidney. Some people who want to be kidney donors do not have a certain person in mind to receive the kidney. This is called a non-directed donation.

Often, non-directed donations start an “organ donation chain” where on average 15 kidneys are donated and received. In donation chains, the non-directed kidney donation goes to someone who had a donor lined up, but the donor was not a compatible match. That donor then “pays forward” their donation to someone else who is waiting.

For Liver Transplant

Most living liver donors are a family member or friend. Mayo Clinic requires that living liver donors have a relationship with the person receiving part of their liver.

Whatever your reason is for considering living donation, it’s important to understand the process and take time to make your decision.

Making the decision

To help you decide, you may want to reach out to family members, close friends, someone else who has considered donating an organ, a social worker or counselor. It may be helpful to ask yourself these questions:

  • How do I feel about donating?
  • Can I afford to take the time off work to rest and recover after surgery?
  • Do I know enough about the process to make an educated decision?
  • How may the donation change my relationship with the person I am donating to?
  • Are there current health concerns that might keep me from donating?
  • Do I have support from family members or close friends to help me through this process?
  • How will I feel if it is determined I am not able to donate?
  • Am I willing to take part in an organ donation chain if I’m not a match with the person I wanted to donate to?
  • What if the organ that I donate doesn’t work well? How would I deal with that?

At Mayo Clinic, you will have an Independent Living Donor Advocate to help you determine if organ donation is the right choice for you.

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What to expect as a donor

You and the person you are donating to (your recipient), will have a variety of appointments and tests to make sure you are a good match, and to prepare for the transplant.

Tests and screening

The first step to becoming a living donor is to have a blood test. This test helps determine if your blood type matches with the recipient. If your blood test results are acceptable, you then come to Mayo Clinic for tests and appointments to see whether you can be a donor.

While these tests are most commonly done, other tests may be done to help determine if donating is an option for you.

The procedure

At Mayo Clinic, surgery to donate a kidney is usually done using several small incisions instead of one larger one. This surgery is called laparoscopic surgery, which reduces the time needed to recover following surgery.

During a living-donor liver transplant, a surgeon places the part of your liver that is removed into the recipient after all of his or her liver is removed. It usually takes several weeks to several months for the liver to return to its normal size in both the recipient and the donor.

Risks

As with any surgery, there are risks involved. Some of the risks of this surgery are the same as any surgery: infection, bleeding and blood clots. Rare complications from surgery include heart attack, stroke and death. Your team will discuss risks with you in detail during your evaluation. Although there are risks involved, most donors do not have long-term problems after they donate.

It is common for people who have donated a kidney to feel many emotions after surgery. You may feel worried, frustrated or angry. You might feel guilty or depressed if the person you donated to does not do well after surgery. These emotional responses are normal. Your donor team can help.

Recovery

Liver donors usually stay in the hospital for four to seven days after surgery, while kidney donors typically stay two to three days. Most people can resume normal activity within six weeks and can return to work within six to eight weeks, depending on the type of work. Ask your donor team what you can expect with recovery and follow-up care.

Should I stop taking my medication(s) before the evaluation or the surgery?

You should not stop any prescription medication unless advised to do so by your physician. Tell your donor team about all prescription and over-the-counter medications you are currently taking.

What should I bring with me to the hospital?

Bring a basic toiletry bag for your use in the hospital, as well as comfortable, loose fitting clothes for when you are ready to go home. Because the hospital will already have your insurance information, there is no need to bring any documentation unless you are specifically asked. Leave all jewelry and other valuables at home.

Should I stop smoking before my surgery?

Smoking slows healing. If you currently smoke, stop. This includes all tobacco products including chewing tobacco. If you are a current tobacco user, talk to your donor team about resources to help you quit.

Should I stop drinking alcohol?

It’s recommended to stop drinking alcohol before surgery. Don’t drink alcohol after the surgery until checking with your donor team. Your alcohol use, both current and previous, is discussed during evaluation.

Financial Information

It’s natural to be concerned about expenses related to your donation. The following information will give you a better sense of what to expect.

Lost work time

Before your donation, tell your employer about the surgery. Ask about disability insurance coverage, medical leave and possible paid time off. When returning to work, tell your employer about any restrictions or short-term special needs.

Donor and recipient costs

Most medical costs related to living donation are covered by the recipient’s insurance. Any medical issues found during your evaluation that are not related to the donation will need to be covered by your personal health insurance. For this reason, the transplant center may ask for your health insurance information before or during your evaluation. Future health problems may not be covered by the recipient’s insurance and life-long medical follow-up will become your financial responsibility.

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Peer and social support for living donors

Involving your family and friends

Your family and friends can make a difference before and after you donate. By keeping them involved in the donation process, you open yourself up to encouragement, support and a better emotional recovery.

Finding a support community

Sharing your concerns, fears, struggles, experiences and triumphs with other donors and recipients can be comforting. Support is available through a variety of ways, including one-on-one support, group gatherings, online communities and more. Ask your nurse coordinator or social worker for support resources.

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