2025 Research Highlights: Cognitive impairment predictor tool

Dec 9 12:00pm | Nick Rethemeier | @nrethemeier | Comments (4)

In November, Mayo Clinic Alzheimer’s Disease Research Center researchers announced they created a tool that can predict someone’s risk of cognitive impairment. The research was published in The Lancet Neurology using data from the Mayo Clinic Study of Aging, a long-term study focused on residents living in Olmsted County, Minnesota and studying how they age.

The prediction model uses several factors including:

  • Age
  • Sex
  • Genetic risk (determined by APOE genotype)
  • Brain amyloid levels (determined through PET scans)

Using these factors, the model calculates both someone’s risk of developing dementia within ten years and over their lifetime.

It is important to note that this is still a research tool and is not something used in a clinic. If you would like to learn more about the predictor tool, the Mayo Clinic News Network has a helpful article which describes it in more detail.

Interested in more newsfeed posts like this? Go to the Dementia Hub blog.

This article was very interesting! And thank you for giving the link to the entire article

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Hmmm. I must have cognitive decline because I can’t find the link to the article lol. Can anyone guide me? It sounds very interesting

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Profile picture for laura1970 @laura1970

Hmmm. I must have cognitive decline because I can’t find the link to the article lol. Can anyone guide me? It sounds very interesting

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@laura1970 If you click on the word "article" in the last sentence, it will take you to the article. I have also provided the hyperlink below:
https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-scientists-create-tool-to-predict-alzheimers-risk-years-before-symptoms-begin/

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