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Zetia side effects

Posted by zephyr2309 @zephyr2309, Apr 28 7:10pm

Hello - anyone experience side effects with Zetia? I cannot take any statins due to side effects; believe me, my cardiologist and I have tried them all over the years. I am on Praluent, a PCSK9 inhibitor ( like Repatha). Decided to try Zetia, and after almost two weeks, I’m ready to stop. Grateful for Praluent, which I can tolerate. I have HeFH.
Thanks

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zephyr2309 | @zephyr2309 | May 1 9:22am
In reply to @valentine5358 "I was prescribed ezetimibe 10 mg to be taken with rosuvastatin 40 mg 1/2 tab daily..." + (show)
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I was prescribed ezetimibe 10 mg to be taken with rosuvastatin 40 mg 1/2 tab daily in Mar. 2026. After about 10 days of this medication, I noticed a red swollen area on inside of my left wrist up to my elbow; the rash spread to my right arm in same location. It was was inflamed; I took my temperature to be sure I had no fever. (my temp. was normal) The rash disappeared about 3-5 days after med was discontinued. Directions from the pharmacy advised any rash was an sign of an allergy to the drug; should discontinue taking and let physicians know immediately. I did as directed and cardiology team is considering an alternative. I'm still taking the statin 1/2 tab with no side effects.
I have had stable angina since 2006 when angioplasty and a stent was placed in left anterior artery for blockage. I had been taking atorvastatin 40mg, metoprolol 25 mg, lisinopril 10 mg, aspirin 81mg. Last summer I had symptoms due to a clot; no apparent damage to my heart. Plavix 75 mg added and increased metoprolol to 50mg last summer with no side effects.

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@valentine5358
Thank you for your response. If I could take statins, I would. But I also think the Zetia gave me influenza-type side effects. Due to medication I was taking for breast cancer, I ended up with cardiac problems. Stent in LAD in 2023. Still on Brilinta. I was already on metoprolol because the BC medications gave me a really rapid heart rate. The human body is incredible and so individual. Thanks again. Be well.

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