Why change from Hydroxyurea to Jakafi (ruxolitinib)?
Have PV with JAK2 for three years. Take Hydroxyurea 500mg plus 81 mg aspirin daily. Get phlebotomy if my hematocrit number is near 45. This is only about every other month. Now my doctor said I’m iron deficient and wants to change medication to Jakof. Trying to avoid phlebotomies. I’m concerned about changing medication. I have no problem with what treatment I’ve had now for a year. The iron deficiency was recently diagnosed. I was told if I took iron tablets it would increase my hematocrit number. I’m eating iron rich foods and even though I have fatigue I’m doing fine. I’m 72 and usually very energetic but an afternoon nap is necessary. Why change meds? Seeing doctor today. Will come back to let you know what she says. Hug to all with this disease.
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Hi @1hostahoney I hope you were able to talk with your doctor and get some reassuring answers about the switch from Hydroxyurea to Jakafi. I know changing meds can be stressful. But both are great meds for PV though they do have different mechanisms of action. So your doctor may want to swap them to see if one is a better fit for you. What did you learn at your appointment this past week?
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