Why are urologists dismissive about Decipher?

That’s the nature of machine learning algorithms. They are black boxes. Sometimes they layer ‘reasoning’ over the results but that’s really not an accurate assessment of what actually goes on behind the scenes.

@robertov based on what you said, what is your opinion of Decipher Score?

@service1010
If you have a Gleason seven Or eight And they do or don’t find other things in your biopsy then getting a decipher score can give you a good idea about what’s going to happen with your prostate cancer future. Whether or not a reoccurrence is probable to happen.

If you have a lot of aggressive things in your biopsy it may not make sense to do, since it’s probably going to come back anyway.

If you are a Gleason 9 or 10 then a reoccurrence is probably going to happen, so the decipher score isn’t really as relevant.

@jeffmarc Gleason Grade 3 Gleason Score 4+3 6 of 12 cores (others 3+3 or benign), PSA < 4. Deceipher score, just received yesterday .96

@robertov based on what you said, what is your opinion of Decipher Score?

@jeffmarc Gleason Grade 3 Gleason Score 4+3 6 of 12 cores (others 3+3 or benign), PSA < 4. Deceipher score, just received yesterday .96

@service1010
In your case, it made a lot of sense to do decipher. You did have a good percentage of cores With 4+3. I suspect they found other things in your biopsy in order to get up to .96

Were any of these things found in the biopsy like intraductal, cribriform, Seminal vesicle invasion, EPE or ECE. (Extraprostatic extensions extra capsular extensions)
,

Those could mean that your cancer was more aggressive and could explain the .96 with a 4+3.

@service1010 means you might be well advised to take ADT.

@service1010 I cannot comment. I didn’t have one since with a 4+4, it would not affect my treatment decision. And I’m sorry, I therefore never learned much about it. Silly, really with a career in AI.

@gently Don't want to. lol