Ocrevus or Kesimpta? Which treatment should I choose for MS?

Posted by striblingpaul @striblingpaul, Aug 29 8:33pm

ocrvus or kesimpta doc gave option any advice

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Welcome, @striblingpaul. I'm tagging other members who live with multiple sclerosis, like @sanny @beltonite410 @christinebuchar @shack76 @babette @chris462 @helenlodahl @kip170 @kco @dsheahan1951 to see if they have experience with either Ocrevus or Kesimpta.

According to a clinical trial comparing Kesimpta (ofatumumab) to Ocrevus for the treatment of relapsing forms of multiple sclerosis (RMS) in adults, the main difference is cost and how the drug is administered. Read more here:
– Novartis' Kesimpta to compete with Roche's Ocrevus in MS: https://www.clinicaltrialsarena.com/comment/aan-2021-novartis-kesimpta-trial/

"The safety and efficacy data of Ocrevus is, overall, comparable with that of Kesimpta. The main differentiation between the two drugs is the delivery system and the annual cost of therapy, which is $65,000 for Ocrevus compared to $83,000 for Kesimpta in the US."

Kesimpta is self-injected under the skin once monthly. Ocrevus is given as an intravenous infusion every six months.

Paul, do the factors of cost and the convenience of self-administration help you make your choice?

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