Which Osteo Meds Don't Need to Be Followed Up with More Meds

Posted by aspirecreative @aspirecreative, Jun 25, 2025

I see that with some meds, like alendronate, you take a pause after a few years and then see if you need to continue or take another med. With others, like Evenity or Prolia, it seems once you start, you need to be on some kind of osteo med for life. I am puzzled by this, it sounds like if you don't start another med immediately, you are worse off as you start losing bone density right away. Do those drugs change something in your bone chemistry that causes fasterloss when you are off of them? And, which meds can you take for a while and then pause, or even stop medicating?
Thank you.

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Profile picture for sl303 @sl303

i am reading all the comments here about this nightmare, have been resisting the meds for ten years now and w last dexa, first where my hips were below 2.5 (now2.9) doctor really pushing the drugs But that whole 'for the rest of your life' thing, o m g I just don't want that. I wonder if the bioidentical HRT idea is better because maybe that does not have the rebound effect, where you lose once you stop Because that bone would be genuine.

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I have the same numbers as you and will not do the drugs. I have been on HRT for 2 years. You cannot just take bone drugs and not do anything else. It is a whole body approach. All the drugs stop working after awhile, that is why they switch out. The scary ones are the drugs that you lose more bone loss after you stop.

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Profile picture for dvargo @dvargo

I have the same numbers as you and will not do the drugs. I have been on HRT for 2 years. You cannot just take bone drugs and not do anything else. It is a whole body approach. All the drugs stop working after awhile, that is why they switch out. The scary ones are the drugs that you lose more bone loss after you stop.

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Were you post menopausal more than 10 years? And what type of doctor gave you the HRT? I sure would be interested.

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I am 76 and a gyn gave me HRT.

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Is it possible to build bone strength through exercise while on Prolia?

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Profile picture for mattiejames @mattiejames

Is it possible to build bone strength through exercise while on Prolia?

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@mattiejames Definitely. Look up Dr Lisa Moore on YouTube for exercises if you're just starting out.

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Profile picture for brendammc @brendammc

Were you post menopausal more than 10 years? And what type of doctor gave you the HRT? I sure would be interested.

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@brendammc

I started bhrt at 77. I went ino menopause at 38. I am using a functional medicine provider. The thinking on length of time post menopause.

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Profile picture for brendammc @brendammc

Were you post menopausal more than 10 years? And what type of doctor gave you the HRT? I sure would be interested.

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@brendammc
look for a gyn, member of The Menopause Society who is experienced with HRT.

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