When to be concerned about eGFR?

Posted by sharlea1313 @sharlea1313, Sep 6, 2025

I’m so confused. My GFR dropped rapidly over a year and seems to have settled into the the mid-50s. I was in Emerg last wk for something unrelated and a GFR was part of the bloodwork, result 53. The doctor said my kidney function wasn’t optimal. I asked her if she had a patient with my numbers would she refer them to a nephrologist. She said no, basically it’s normal. Then I saw my GP and asked at what point should I be concerned. He said I don’t have to be concerned until he’s concerned and he will let me know if that happens. Well, shouldn’t I be doing something now to try to prevent further damage? He said it’s a result of my high blood pressure, but then lowered one of my BP meds. He started me on a statin for cholesterol, but started me at 20 mg/day. The pharmacist said normally they start at 5 mg to see how the patient tolerates it and then gradually increase it. I took 20 mg yesterday and now I have diarrhea. I have been told by many doctors and nurses that I am so lucky to have my GP because he is a brilliant doctor. I don’t feel so lucky, but I guess I have to trust his judgment, especially since the doctor in Emerg said the same thing. My next blood work will be in 6 months so I will wait to see what happens then. In the meantime I am going to act as though my situation is important and will try to follow a basic renal diet. If Stages 1, 2, and 3a are insignificant why do they even have them?

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Profile picture for jeg321 @jeg321

How concerned should we be with the individual matrix verses the overall matrix in the Comprehensive Metabolic panel??
Also, can anyone speak to having gallbladder removal and its potential impact on kidney functions if any??

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My eGFR went from 39 to 17 in 6 months and no one can tell me why
Within a month it is up to 22. Still no answers

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Anything change for it to go up? Stop supplements?

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Profile picture for jeg321 @jeg321

How concerned should we be with the individual matrix verses the overall matrix in the Comprehensive Metabolic panel??
Also, can anyone speak to having gallbladder removal and its potential impact on kidney functions if any??

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@jeg321

I had my gallbladder removed in 1977. No stones. It was malformed so my doctor thought it malfunctioned. It was supposed to dump bile into the intestine when I ate but mine didn't work well. As a result it got infected.

My nephrologists have never commented on my lack of a gallbladder. (I have one nephrologist at my local HMO who also functions as a second "primary care physician". He manages gout and pseudogout, too, instead of Rheumatology which rejected me because I hadn't had a tophus, just a sore toe for three months (that the Foot and Ankle doctor said x-rays didn't show anything broken because nothing was broken) and high uric acid. He seems very well rounded, bright and is very personable. He was responsible for the CKD diagnosis. The second one is at Mayo Rochester and is important because he is the only doctor I've met who has any familiarity with the CKD I have, immunotactoid glomerulopathy. I think I am one of 10 patients in the work with that disorder.)

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These stages are not insignificant. It is a way to monitor your kidney function. A GFR in the 50's for anyone over age 70 is normal in many cases. Kidney function slowly declines for everyone as we age; a lot depends on what other comorbidities you may have. Keep monitoring. Stop salt and stop NSAIDS.

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I went through the same fears as you a couple of years back. My egfr was at 44 when it happened. My doctor also told me not to be concerned yet. One year later my eGFR number had fallen down to 31 and I was then referred to a Nephrologist. I did some research and learned that: Referral to a nephrologist is generally recommended when eGFR falls below 30 mL/min/1.73 m² (CKD Stages 4 and 5), indicating severe kidney damage. However, earlier referral is necessary (often at eGFR < 60) if there is rapid decline, significant proteinuria, or uncontrollable complication. I hope this helps you. The one thing you can do at this point is to look into the Renal Diet. It does help slow down failure of the kidneys, often, but not always. I began Jardiance last year which also helped to slow the progression of kidney damage. Please update us when you can. There are things you can do right now to help slow it and there are several books out that explain it. Hope this helps a little. Blessings to you.

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Profile picture for knitpurl1 @knitpurl1

My eGFR went from 39 to 17 in 6 months and no one can tell me why
Within a month it is up to 22. Still no answers

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Thanks for the hug
HUG Heavenly Unique Gift

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